LEADER 03674nam  2201045z- 450 
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005 20240107235129.0
035   $a(CKB)5400000000045986
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76486
035   $a(EXLCZ)995400000000045986
100   $a20202201d2021      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aInsulin-Like Growth Factors in Development, Cancers and Aging
210   $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021
215   $a1 electronic resource (196 p.)
311   $a3-0365-0770-1 
311   $a3-0365-0771-X 
330   $aThis Special Issue of Cells on ?Insulin-Like Growth Factors in Development, Cancers and Aging? provides a collection of modern articles dealing with the role of insulin-like growth factors (IGF1) in cancer biology, aging and development. Featured articles explore basic and clinical aspects of the IGF1 system, including post-genomic analyses as well as novel approaches to target the IGF1 receptor (IGF1R) in oncology.   The present Special Issue highlights some of the most important topics in the broad area of IGF research, including the role of IGF1 in aging and longevity, attempts to target the IGF1 axis in oncology, the role of IGF-binding proteins, structural aspects of IGF-II, etc. We trust that this assembly of articles will be of great help to students, basic researchers and practitioners.
606   $aResearch & information: general$2bicssc
606   $aBiology, life sciences$2bicssc
610   $aIGF-I
610   $aIGF-II
610   $ainsulin
610   $aIGF-IR
610   $aIRs
610   $atyrosine kinase receptor
610   $aGPCRs
610   $ahybrids
610   $aphosphorylation
610   $aG-proteins
610   $a?-arrestins
610   $afunctional RTK/GPCR hybrid
610   $anuclear translocation
610   $aIGF-I receptor
610   $asignaling
610   $atargeted therapeutics
610   $aIGF-Trap
610   $aIGF system
610   $aIGFBP-3
610   $aIGFBP-3R
610   $aTMEM219
610   $aanti-tumor
610   $aanti-metastatic
610   $aagonists
610   $amAb therapy
610   $aIGF-1
610   $aIGFBP-1
610   $aolder adults
610   $alongevity
610   $ahealth-span
610   $aage-related disease
610   $acognitive impairment
610   $adiabetes
610   $amitochondria
610   $agrowth hormone
610   $ainsulin-like growth factor-1
610   $aaging
610   $aoxidative stress
610   $asenescence
610   $alongitudinal study
610   $aIGFBP
610   $amouse models
610   $askeletal muscle
610   $aMSCs
610   $amyogenesis
610   $aglucose regulated protein (GRP) 94
610   $ainsulin-like growth factor
610   $aobligate chaperone
610   $ahypertrophy
610   $aatrophy
610   $acachexia
610   $amuscle regeneration
610   $aautophagy
610   $aIGF-1R
610   $ainsulin receptor
610   $aIR-A
610   $astructural studies
610   $areceptor activation
615  7$aResearch & information: general
615  7$aBiology, life sciences
700   $aWerner$b Haim$4edt$01287877
702   $aWerner$b Haim$4oth
906   $aBOOK
912   $a9910557735703321
996   $aInsulin-Like Growth Factors in Development, Cancers and Aging$93020512
997   $aUNINA