LEADER 06017nam 2201513z- 450 001 9910557716703321 005 20231214133120.0 035 $a(CKB)5400000000046158 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76898 035 $a(EXLCZ)995400000000046158 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aNeuroprotection: Rescue from Neuronal Death in the Brain 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 electronic resource (408 p.) 311 $a3-0365-1994-7 311 $a3-0365-1995-5 330 $aDear Colleagues, The brain is vulnerable to injury. Following injury in the brain, apoptosis or necrosis may occur easily, leading to various functional disabilities. Neuronal death is associated with a number of neurological disorders including hypoxic ischemia, epileptic seizures, and neurodegenerative diseases. The brain subjected to injury is regarded to be responsible for the alterations in neurotransmission processes, resulting in functional changes. Oxidative stress produced by reactive oxygen species has been shown to be related to the death of neurons in traumatic injury, stroke, and neurodegenerative diseases. Therefore, scavenging or decreasing free radicals may be crucial for preventing neural tissues from harmful adversities in the brain. Neurotrophic factors, bioactive compounds, dietary nutrients, or cell engineering may ameliorate the pathological processes related to neuronal death or neurodegeneration and appear beneficial for improving neuroprotection. As a result of neuronal death or neuroprotection, the brain undergoes activity-dependent long-lasting changes in synaptic transmission, which is also known as functional plasticity. Neuroprotection implying the rescue from neuronal death is now becoming one of global health concerns. This Special Issue attempts to explore the recent advances in neuroprotection related to the brain. This Special Issue welcomes original research or review papers demonstrating the mechanisms of neuroprotection against brain injury using in vivo or in vitro models of animals as well as in clinical settings. The issues in a paper should be supported by sufficient data or evidence. Prof. Bae Hwan Lee Guest Editor 517 $aNeuroprotection 606 $aResearch & information: general$2bicssc 610 $aglobal cerebral ischemia 610 $aamiloride 610 $asodium-hydrogen exchanger-1 610 $azinc 610 $aneuronal death 610 $aneuroprotection 610 $aneurodegenerative disorder 610 $acholine acetyltransferase (ChAT) 610 $atrimethyltin (TMT) 610 $abean phosphatidylserine (Bean-PS) 610 $abrain-derived neurotrophic factor 610 $amoderate hypoxia 610 $aphysical exercise 610 $apsychomotor function 610 $areaction time 610 $acortisol 610 $acatecholamines 610 $anitrite 610 $aendotheline-1 610 $alactate 610 $apyridoxine deficiency 610 $aischemia 610 $agerbil 610 $ahomocysteine 610 $acell death 610 $aglia 610 $aneurogenesis 610 $aN-acetyl-l-cysteine 610 $atransient receptor potential melastatin 2 610 $aneurodegeneration 610 $aAlzheimer's disease 610 $ametabolic disease 610 $aadiponectin 610 $ainsulin 610 $aantioxidants 610 $astroke 610 $apreventive gene therapy 610 $aadenoviral vector 610 $aVEGF 610 $aGDNF 610 $aNCAM 610 $ahuman umbilical cord blood mononuclear cells 610 $aantioxidant 610 $abrain 610 $aneurodegenerative disease 610 $aoxidative stress 610 $aPGC-1? 610 $avascular endothelial growth factor 610 $avascular endothelial growth factor receptor 2 610 $aPI3K/AKT 610 $aMEK/ERK 610 $astatus epilepticus 610 $ahippocampus 610 $amiddle cerebral artery occlusion 610 $areperfusion injury 610 $alipid emulsion 610 $aexcitotoxicity 610 $aapoptosis 610 $aGPR4 receptor 610 $aMPP+ 610 $aParkinson's disease 610 $aCRISPR/cas9 610 $aischemic stroke 610 $ablood brain barrier 610 $ananoparticle-based drug delivery 610 $abrain targeting 610 $aBDNF 610 $amiRNAs 610 $asynaptic plasticity 610 $adepression 610 $aglioblastoma 610 $aastrocytes 610 $aastrocytic networks 610 $aconnexin 43 610 $acalcium activity 610 $aneural injury 610 $animodipine 610 $asubarachnoid haemorrhage 610 $aacid-sensing ion channels 610 $aoxygen-glucose deprivation 610 $aliver growth factor 610 $ainflammation 610 $amicroglia 610 $aTg2576 transgenic mice 610 $aamyloid-beta 610 $aoculomotor system 610 $atrophic factors 610 $amotoneurons 610 $aaxotomy 610 $aamyotrophic lateral sclerosis 610 $aelectroneutral transport 610 $acation-chloride cotransporters 610 $aKCCs 610 $aNKCCs 610 $aWNK-SPAK/OSR1 610 $aascorbic acid 610 $aaging 610 $aorganotypic hippocampal slice culture 615 7$aResearch & information: general 700 $aLee$b Bae Hwan$4edt$01311353 702 $aLee$b Bae Hwan$4oth 906 $aBOOK 912 $a9910557716703321 996 $aNeuroprotection: Rescue from Neuronal Death in the Brain$93030280 997 $aUNINA