LEADER 03774nam 2200685Ia 450 001 9910782987903321 005 20230721005356.0 010 $a1-4443-6059-0 010 $a1-282-00763-7 010 $a9786612007637 010 $a1-4443-0357-0 010 $a1-4443-0358-9 035 $a(CKB)1000000000722814 035 $a(EBL)416492 035 $a(OCoLC)476248454 035 $a(SSID)ssj0000231079 035 $a(PQKBManifestationID)11187388 035 $a(PQKBTitleCode)TC0000231079 035 $a(PQKBWorkID)10216957 035 $a(PQKB)10180872 035 $a(MiAaPQ)EBC416492 035 $a(Au-PeEL)EBL416492 035 $a(CaPaEBR)ebr10300898 035 $a(CaONFJC)MIL200763 035 $a(EXLCZ)991000000000722814 100 $a20080529d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aQuality in laboratory hemostasis and thrombosis$b[electronic resource] /$fSteve Kitchen, John D. Olson, F. Eric Preston 210 $aChichester, West Sussex ;$aHoboken, NJ $cWiley-Blackwell$d2009 215 $a1 online resource (227 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-6803-X 320 $aIncludes bibliographical references and index. 327 $aContents; Contributors; Foreword; Preface; 1: General quality planning in the hemostasis laboratory; 2: Hemostasis test validation, performance and reference intervals; 3: International Standards in hemostasis; 4: Sample integrity and preanalytical variables; 5: Internal quality control in the hemostasis laboratory; 6: External quality assessment in hemostasis: its importance and significance; 7: Initial evaluation of hemostasis: reagent and method selection; 8: Point-of-care testing in hemostasis; 9: Assay of factor VIII and other clotting factors 327 $a10: Application of molecular genetics to the investigation of inherited bleeding disorders11: Standardization of D-dimer testing; 12: Diagnostic assessment of platelet function; 13: Laboratory evaluation of von Willebrand disease: phenotypic analysis; 14: Laboratory analysis of von Willebrand disease: molecular analysis; 15: Dilemmas in heritable thrombophilia testing; 16: Evaluation of antiphospholipid antibodies; 17: Monitoring heparin therapy; 18: Monitoring oral anticoagulant therapy; 19: Monitoring new anticoagulants; 20: Detecting and quantifying functional inhibitors in hemostasis 327 $aIndex 330 $a""Over the last decades, major progress has been made in quality assurance of hemostatic laboratory assays. This book will be an indispensable part of every hemostasis laboratory, where, given its hands-on nature, it will rarely sit to get dusty on the shelves.""-Frits R. Rosendaal, Leiden University Medical Center The hemostasis laboratory has a vital role in the diagnosis and management of patients with familial and acquired hemorrhagic and thrombotic disorders. Its role in the monitoring traditional anticoagulant therapy as well as therapy using new anticoagulants presents 606 $aBlood coagulation disorders$xDiagnosis 606 $aBlood$xAnalysis$vLaboratory manuals 606 $aHemostasis 606 $aThrombosis 615 0$aBlood coagulation disorders$xDiagnosis. 615 0$aBlood$xAnalysis 615 0$aHemostasis. 615 0$aThrombosis. 676 $a616.1/57075 700 $aKitchen$b Steve$cDr.$0860323 701 $aOlson$b John David$f1944-$0860324 701 $aPreston$b F. E$0860325 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910782987903321 996 $aQuality in laboratory hemostasis and thrombosis$91919643 997 $aUNINA LEADER 04533nam 2201177z- 450 001 9910557704403321 005 20220111 035 $a(CKB)5400000000046235 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/77116 035 $a(oapen)doab77116 035 $a(EXLCZ)995400000000046235 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aFucoidans 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 online resource (254 p.) 311 08$a3-0365-2410-X 311 08$a3-0365-2411-8 330 $aFucoidans are a group of fucose-containing sulfated polysaccharides found in many species of brown seaweeds, with numerous bioactive properties. As a highly bioactive seaweed substance with many promising physiological activities, fucoidans have attracted attention from many industries all over the world. Even though fucoidans are a rich source of bioactive properties, the structural properties and bioactive mechanisms of fucoidans are poorly understood. Therefore, novel studies that either characterize the physical properties or biological activities of fucoidans will fill the knowledge gap between industrial applications and the scientific background of those applications. Both purified and partially purified fucoidans isolated from brown seaweeds present high potential as preventative and therapeutic agents against number of chronic diseases, due to their anti-inflammatory, antioxidant, anticancer, neuroprotective, antiviral, antimicrobial, and anticoagulative properties. This Special Issue is aimed at presenting updated information on well-documented studies of the structural characterization and major biological actions relevant for medical, cosmeceutical, and pharmaceutical applications that fucoidans isolated from brown seaweed can offer. 606 $aMedicine and Nursing$2bicssc 610 $aadriamycin 610 $aage-related macular degeneration 610 $aanti-lung cancer 610 $aanticancer 610 $aantioxidant 610 $aapoptosis 610 $aascorbic acid 610 $abioactivities 610 $abrown algae 610 $acancer 610 $acarbohydrate 610 $aCelluclast 610 $achitosan 610 $aCladosiphon okamuranus Tokida 610 $adopamine neurons apoptosis 610 $aDR4 610 $aenzymatic purification 610 $aepithelial mesenchymal transition 610 $aextraction 610 $afibroblast growth factor-2 610 $afucoidan 610 $afucoidan from Ascophyllum nodosum 610 $afucoidans 610 $afucose 610 $aFucus distichus subsp. evanescens 610 $aHaCaT cells 610 $aHelicobacter pylori 610 $ahuman lung carcinoma A-549 cells 610 $ahydrogen peroxide 610 $aIgA 610 $ain vitro and in vivo evaluation 610 $ainfrared spectroscopy 610 $aLaminaria digitata 610 $alow-molecular-weight fucoidan 610 $aMaldives 610 $ametastasis 610 $amicrobiota 610 $amitochondrial pathway 610 $amozuku 610 $amucin 610 $an/a 610 $ananoparticles 610 $anatural defenses 610 $anephrotic syndrome 610 $aoxidative stress 610 $aPadina boryana 610 $aPhaeophyta 610 $aphenolic metabolism 610 $aphenylalanine ammonia-lyase 610 $aPI3K-Akt 610 $apolyelectrolyte multilayer 610 $apostprandial hyperglycemia 610 $aproduction 610 $apsoriasis 610 $aquartz crystal microbalance 610 $aretinal pigment epithelium 610 $aROS 610 $aSaccharina latissima 610 $asargassum 610 $aSargassum crassifolium 610 $aSGLT1 610 $aSri Lankan algae 610 $asulfated heterosaccharide 610 $asulfated polysaccharide 610 $asulfated polysaccharides 610 $aTraf3ip2 610 $aurinalysis 610 $aUVB irradiation 610 $aVEGF 610 $azebrafish 615 7$aMedicine and Nursing 700 $aJeon$b You-Jin$4edt$01332366 702 $aJeon$b You-Jin$4oth 906 $aBOOK 912 $a9910557704403321 996 $aFucoidans$93040894 997 $aUNINA