LEADER 04212nam 2200997z- 450 001 9910557688303321 005 20240107235808.0 035 $a(CKB)5400000000044649 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/77103 035 $a(EXLCZ)995400000000044649 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aExtension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 electronic resource (208 p.) 311 $a3-0365-2346-4 311 $a3-0365-2345-6 330 $aMalnutrition is becoming a more prominent health problem, with an increasing number of elderly CKD patients being put on dialysis. In addition, the presence of inflammation, sarcopenia/frailty, diabetes, and CVD is a definite and independent risk factor associated with higher mortality in this population. Although the restriction of protein intake has been recommended to protect eGFR decline, hyperphosphatemia, and hyperkalemia in CKD patients, it might accelerate the loss of skeletal muscle and adipose mass, leading to a poor prognosis. Therefore, flexible responses are considered regarding whether protein restriction should be continued or loosened in pre-dialysis CKD patients. In undernourished elderly patients undergoing hemodialysis, sufficient calorie/protein intake is necessary to counteract the development of sarcopenia/frailty. It is expected that the application of new drugs including phosphate binders and potassium chelators may achieve both a high enough intake and balanced levels of phosphate and potassium. Furthermore, the improvement of deficient micronutrients and poor appetite is also necessary. Comprehensive care is essential for the wellbeing of elderly patients undergoing hemodialysis. The topicof this Special Issue is ?Extension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life?. 606 $aMedicine$2bicssc 610 $ahypertension 610 $abody weight 610 $amortality 610 $asodium 610 $adialysis 610 $amalnutrition 610 $aprotein energy wasting (PEW) 610 $asarcopenia 610 $acarnitine 610 $acarnitine deficiency 610 $aend-stage kidney disease 610 $aperitoneal dialysis 610 $ahemodialysis 610 $afrailty 610 $aprotein energy wasting 610 $ahypercatabolism 610 $arenal rehabilitation 610 $aexercise 610 $asarcopenia and frailty 610 $anutritional support 610 $aprotein synthesis 610 $amuscle physiology 610 $aphysical activity 610 $aexercise tolerance 610 $aquality of life 610 $askeletal muscle 610 $aaging 610 $achronic kidney disease 610 $adiabetes 610 $aCKD-MBD 610 $aFGF23 610 $aaKlotho 610 $aphosphate-binder 610 $azinc 610 $acardiovascular disease 610 $apotassium 610 $apotassium excretion 610 $ablood pressure 610 $asalt 610 $aCKD 610 $afat mass 610 $avisceral fat 610 $asubcutaneous fat 610 $anutrition 610 $abody mass index 610 $aobesity paradox 610 $amagnetic resonance imaging 610 $adiffusion tensor imaging 610 $aarterial spin labeling 610 $ablood oxygenation level-dependent 610 $anutritional status 610 $adialysis patients 610 $aclinical malnutrition 610 $aolder individuals 615 7$aMedicine 700 $aInaba$b Masaaki$4edt$01323479 702 $aMori$b Katsuhiko$4edt 702 $aInaba$b Masaaki$4oth 702 $aMori$b Katsuhiko$4oth 906 $aBOOK 912 $a9910557688303321 996 $aExtension of Healthy Life Span of Dialysis Patients in the Era of a 100-Year Life$93035604 997 $aUNINA