LEADER 04648nam 2201429z- 450 001 9910557648103321 005 20231214132845.0 035 $a(CKB)5400000000044972 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69291 035 $a(EXLCZ)995400000000044972 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aKilling Cancer$eDiscovery and Selection of New Target Molecules 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 electronic resource (302 p.) 311 $a3-03943-440-3 311 $a3-03943-441-1 330 $aDespite the efficiency of current cancer treatments, cancer is still a deadly disease for too many. In 2008, 7.6 million people died of cancer; with the current development, it is estimated that the annual cancer death number will grow to 13 million by 2030. There is clearly a need for not only more research but also more innovative and out of the mainstream scientific ideas to discover and develop even better cancer treatments. This book presents the collective works published in the recent Special Issue entitled ?Killing Cancer: Discovery and Selection of New Target Molecules?. These articles comprise a selection of studies, ideas, and opinions that aim to facilitate knowledge, thoughts, and discussion about which biological and molecular mechanisms in cancer we should target and how we should target them. 517 $aKilling Cancer 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 610 $aferlin 610 $amyoferlin 610 $adysferlin 610 $aotoferlin 610 $aC2 domain 610 $aplasma membrane 610 $asulconazole 610 $aNF-?B 610 $aIL-8 610 $amammosphere 610 $abreast cancer stem cells 610 $aAF1Q 610 $aMLLT11 610 $aWNT 610 $aSTAT 610 $aesophageal cancer 610 $aprognosis 610 $amTORC1 610 $amTORC2 610 $ametabolism 610 $arapalogs 610 $amTOR inhibitors 610 $acancer metabolism 610 $amTOR in immunotherapy 610 $anutrient metabolism 610 $akinase inhibitors 610 $amTOR signaling 610 $aMAPK kinase 610 $aERK1 610 $aERK2 610 $aCD domain 610 $aRolled 610 $aSCH772984 610 $aVRT-11E 610 $asevenmaker 610 $acancer therapy 610 $aEMT 610 $alysosome 610 $alysosome-mediated invasion 610 $aMZF1 610 $aphosphorylation 610 $aPAK4 610 $aSUMOylation 610 $atranscription factor 610 $azinc finger 610 $aglucocorticoids 610 $a3D growth 610 $anuclear factor kappa-light-chain-enhancer of activated B-cells (NF-?B) 610 $aepithelial-mesenchymal transition 610 $aanoikis 610 $aproliferation 610 $atargeted cancer therapy 610 $adisulfiram 610 $aNPL4 610 $areplication stress 610 $aDNA damage 610 $aBRCA1 610 $aBRCA2 610 $aATR pathway 610 $aPDAC 610 $aTCIRG1 610 $aATP6V0a3 610 $ainvasion 610 $amigration 610 $amatrix degradation 610 $apH-regulation 610 $aautophagy 610 $amultidrug resistance in cancer 610 $adrug efflux pumps 610 $aATP-binding cassette transporter 610 $abreast cancer resistance protein (BCRP) 610 $aABCG2 610 $apyrazolo-pyrimidine derivative 610 $aSCO-201 610 $acolorectal cancer 610 $aimmunotherapy 610 $ainflammation 610 $amicrosatellite instability 610 $aoncofetal chondroitin sulfate 610 $achondroitin sulfate 610 $acancer 610 $asolid tumors 610 $atarget 610 $apediatric cancer 610 $aVAR2 610 $adexamethasone 610 $athyroid cancer 610 $amicrogravity 610 $aspace environment 615 7$aResearch & information: general 615 7$aBiology, life sciences 700 $aKallunki$b Tuula$4edt$01300030 702 $aKallunki$b Tuula$4oth 906 $aBOOK 912 $a9910557648103321 996 $aKilling Cancer$93025349 997 $aUNINA