LEADER 04681nam  2201453z- 450 
001 9910557648103321
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035   $a(CKB)5400000000044972
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69291
035   $a(oapen)doab69291
035   $a(EXLCZ)995400000000044972
100   $a20202105d2020      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aKilling Cancer$eDiscovery and Selection of New Target Molecules
210   $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020
215   $a1 online resource (302 p.)
311 08$a3-03943-440-3 
311 08$a3-03943-441-1 
330   $aDespite the efficiency of current cancer treatments, cancer is still a deadly disease for too many. In 2008, 7.6 million people died of cancer; with the current development, it is estimated that the annual cancer death number will grow to 13 million by 2030. There is clearly a need for not only more research but also more innovative and out of the mainstream scientific ideas to discover and develop even better cancer treatments. This book presents the collective works published in the recent Special Issue entitled "Killing Cancer: Discovery and Selection of New Target Molecules". These articles comprise a selection of studies, ideas, and opinions that aim to facilitate knowledge, thoughts, and discussion about which biological and molecular mechanisms in cancer we should target and how we should target them.
517   $aKilling Cancer 
606   $aBiology, life sciences$2bicssc
606   $aResearch & information: general$2bicssc
610   $a3D growth
610   $aABCG2
610   $aAF1Q
610   $aanoikis
610   $aATP-binding cassette transporter
610   $aATP6V0a3
610   $aATR pathway
610   $aautophagy
610   $aBRCA1
610   $aBRCA2
610   $abreast cancer resistance protein (BCRP)
610   $abreast cancer stem cells
610   $aC2 domain
610   $acancer
610   $acancer metabolism
610   $acancer therapy
610   $aCD domain
610   $achondroitin sulfate
610   $acolorectal cancer
610   $adexamethasone
610   $adisulfiram
610   $aDNA damage
610   $adrug efflux pumps
610   $adysferlin
610   $aEMT
610   $aepithelial-mesenchymal transition
610   $aERK1
610   $aERK2
610   $aesophageal cancer
610   $aferlin
610   $aglucocorticoids
610   $aIL-8
610   $aimmunotherapy
610   $ainflammation
610   $ainvasion
610   $akinase inhibitors
610   $alysosome
610   $alysosome-mediated invasion
610   $amammosphere
610   $aMAPK kinase
610   $amatrix degradation
610   $ametabolism
610   $amicrogravity
610   $amicrosatellite instability
610   $amigration
610   $aMLLT11
610   $amTOR in immunotherapy
610   $amTOR inhibitors
610   $amTOR signaling
610   $amTORC1
610   $amTORC2
610   $amultidrug resistance in cancer
610   $amyoferlin
610   $aMZF1
610   $an/a
610   $aNF-?B
610   $aNPL4
610   $anuclear factor kappa-light-chain-enhancer of activated B-cells (NF-?B)
610   $anutrient metabolism
610   $aoncofetal chondroitin sulfate
610   $aotoferlin
610   $aPAK4
610   $aPDAC
610   $apediatric cancer
610   $apH-regulation
610   $aphosphorylation
610   $aplasma membrane
610   $aprognosis
610   $aproliferation
610   $apyrazolo-pyrimidine derivative
610   $arapalogs
610   $areplication stress
610   $aRolled
610   $aSCH772984
610   $aSCO-201
610   $asevenmaker
610   $asolid tumors
610   $aspace environment
610   $aSTAT
610   $asulconazole
610   $aSUMOylation
610   $atarget
610   $atargeted cancer therapy
610   $aTCIRG1
610   $athyroid cancer
610   $atranscription factor
610   $aVAR2
610   $aVRT-11E
610   $aWNT
610   $azinc finger
615  7$aBiology, life sciences
615  7$aResearch & information: general
700   $aKallunki$b Tuula$4edt$01300030
702   $aKallunki$b Tuula$4oth
906   $aBOOK
912   $a9910557648103321
996   $aKilling Cancer$93025349
997   $aUNINA