LEADER 04368nam 2200997z- 450 001 9910557644303321 005 20231214133131.0 035 $a(CKB)5400000000045010 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76776 035 $a(EXLCZ)995400000000045010 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCrocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 electronic resource (171 p.) 311 $a3-0365-1806-1 311 $a3-0365-1805-3 330 $aNatural products or organic compounds isolated from natural sources as primary or secondary metabolites have inspired numerous drugs. It is not an overstatement that the majority of medicines in clinics, even in the 21st century, have been derived from natural resources despite the decline of industry research into natural products due to a variety of drawbacks. Saffron crocus, considered to be the most valuable spice by weight, and its bioactive constituents, have been studied for the treatment of a wide range of pathologies, including neuropsychiatric and neurodegenerative disorders, cancer, diabetes, and even cardiovascular diseases. In this book on the chemistry, pharmacology, and therapeutic potential of Crocus sativus L. extract and its constituents, we aimed to assess new advances in the understanding of the therapeutic action of saffron and its constituents in targeting different pathologies. In this context, eight original research articles covering recent advances in the therapeutic actions of saffron and its ingredients in different diseases are reported. Two studies reporting novel methods regarding the bioanalysis of saffron extracts have been included. The collection is completed with two very interesting reviews reporting advances in the fields of schizophrenia and cancer. In conclusion, in this book, we are delighted to have received several contributions that we hope will provide new and interesting information for the scientific community on the chemistry, pharmacology, and therapeutic potential of Crocus sativus L. extract and its constituents. 517 $aCrocus sativus L. Extract and Its Constituents 606 $aMedicine$2bicssc 610 $asaffron 610 $aaffronŽ 610 $adepression 610 $aanxiety 610 $aantioxidant 610 $acrocins 610 $aglucose 610 $a?-pancreatic cells 610 $ainsulin 610 $apck1 610 $aneuroprotective activity 610 $aP2X7 receptor 610 $afraction 610 $aflumazenil 610 $arat 610 $aCrocus sativus 610 $acancer 610 $aanticancer activity 610 $achemoprevention 610 $aclinical trials 610 $apatents 610 $aanesthetic ketamine 610 $amemory 610 $aCrocus sativus L. 610 $aschizophrenia 610 $acrocetin 610 $apubertal testis 610 $aX-rays 610 $aradiotherapy 610 $afertility preservation 610 $aSIRT1 610 $aHuR 610 $aoxidative stress 610 $aautophagy 610 $acrocin 610 $apicrocrocin 610 $asafranal 610 $adietary supplement 610 $anutraceutical 610 $aCrocus sativus L. (Iridaceae) 610 $areversed-phase UPLC 610 $ametabolomics 610 $aHR MS 610 $ainflammatory bowel disease 610 $agut microbiota 610 $acolitis 610 $acytokines 610 $acolorectal cancer 610 $aHCT116 610 $aMLH1 610 $aMSH3 610 $aDNA damage and repair 610 $aapoptosis 615 7$aMedicine 700 $aPitsikas$b Nikolaos$4edt$01332364 702 $aDimas$b Konstantinos$4edt 702 $aPitsikas$b Nikolaos$4oth 702 $aDimas$b Konstantinos$4oth 906 $aBOOK 912 $a9910557644303321 996 $aCrocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential$93040891 997 $aUNINA