LEADER 03241nam  2200889z- 450 
001 9910557628803321
005 20231214133301.0
035   $a(CKB)5400000000045126
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69167
035   $a(EXLCZ)995400000000045126
100   $a20202105d2020      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aHedgehog Signaling in Organogenesis and Tumor Microenvironment
210   $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020
215   $a1 electronic resource (172 p.)
311   $a3-03936-260-7 
311   $a3-03936-261-5 
330   $aThe Hedgehog signaling pathway is an evolutionarily conserved pathway that governs complex developmental processes, including stem cell maintenance, proliferation, differentiation, and patterning. Several recent studies have shown that the aberrant activation of Hedgehog signaling is associated with neoplastic transformation, cancer cell proliferation, metastasis, multiple cancers? drug resistance, and survival rates. This book focuses on several aspects of Hedgehog signaling in organogenesis and the tumor microenvironment, and presents reviews and original papers on recent efforts in the field of Hedgehog signaling.
606   $aMedicine$2bicssc
610   $aCyp26 enzymes
610   $acongenital anomalies
610   $aCRE/LoxP
610   $ahedgehog signaling
610   $amouse models
610   $aretinoic acid
610   $asmoothened
610   $asonic hedgehog
610   $asonic hedgehog (SHH)
610   $aoral squamous cell carcinoma (OSCC)
610   $atumor microenvironment (TME)
610   $atumor-associated macrophages (TAMs)
610   $acancer-associated fibroblasts (CAFs)
610   $atumor-associated angiogenesis
610   $ahedgehog
610   $agrowth plate
610   $aendochondral ossification
610   $achondrocyte
610   $aosteoblast
610   $abone disease
610   $aTMJ
610   $asynovial joint
610   $aarticular disc
610   $aIhh
610   $aPTHrP
610   $aosteoarthritis
610   $aepithelial-mesenchymal interaction (EMI)
610   $aprostate cancer
610   $aexternal genitalia
610   $aandrogen
610   $abasement membrane
610   $abone morphogenetic protein
610   $astem cell
610   $aanimal experiment
610   $afracture healing
610   $acancer stem cells
610   $ahypospadias
610   $aurethra
610   $apenis
610   $abone
610   $ahedgehog signalling
610   $atooth development
610   $aepithelial and mesenchymal interaction
610   $aGli1
610   $amesenchymal stem cell
610   $alineage tracing analysis
610   $astem cell marker
615  7$aMedicine
700   $aShimo$b Tsuyoshi$4edt$01297612
702   $aShimo$b Tsuyoshi$4oth
906   $aBOOK
912   $a9910557628803321
996   $aHedgehog Signaling in Organogenesis and Tumor Microenvironment$93024614
997   $aUNINA