LEADER 03276nam  2200913z- 450 
001 9910557628803321
005 20210501
035   $a(CKB)5400000000045126
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69167
035   $a(oapen)doab69167
035   $a(EXLCZ)995400000000045126
100   $a20202105d2020      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aHedgehog Signaling in Organogenesis and Tumor Microenvironment
210   $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020
215   $a1 online resource (172 p.)
311 08$a3-03936-260-7 
311 08$a3-03936-261-5 
330   $aThe Hedgehog signaling pathway is an evolutionarily conserved pathway that governs complex developmental processes, including stem cell maintenance, proliferation, differentiation, and patterning. Several recent studies have shown that the aberrant activation of Hedgehog signaling is associated with neoplastic transformation, cancer cell proliferation, metastasis, multiple cancers' drug resistance, and survival rates. This book focuses on several aspects of Hedgehog signaling in organogenesis and the tumor microenvironment, and presents reviews and original papers on recent efforts in the field of Hedgehog signaling.
606   $aMedicine$2bicssc
610   $aandrogen
610   $aanimal experiment
610   $aarticular disc
610   $abasement membrane
610   $abone
610   $abone disease
610   $abone morphogenetic protein
610   $acancer stem cells
610   $acancer-associated fibroblasts (CAFs)
610   $achondrocyte
610   $acongenital anomalies
610   $aCRE/LoxP
610   $aCyp26 enzymes
610   $aendochondral ossification
610   $aepithelial and mesenchymal interaction
610   $aepithelial-mesenchymal interaction (EMI)
610   $aexternal genitalia
610   $afracture healing
610   $aGli1
610   $agrowth plate
610   $ahedgehog
610   $ahedgehog signaling
610   $ahedgehog signalling
610   $ahypospadias
610   $aIhh
610   $alineage tracing analysis
610   $amesenchymal stem cell
610   $amouse models
610   $an/a
610   $aoral squamous cell carcinoma (OSCC)
610   $aosteoarthritis
610   $aosteoblast
610   $apenis
610   $aprostate cancer
610   $aPTHrP
610   $aretinoic acid
610   $asmoothened
610   $asonic hedgehog
610   $asonic hedgehog (SHH)
610   $astem cell
610   $astem cell marker
610   $asynovial joint
610   $aTMJ
610   $atooth development
610   $atumor microenvironment (TME)
610   $atumor-associated angiogenesis
610   $atumor-associated macrophages (TAMs)
610   $aurethra
615  7$aMedicine
700   $aShimo$b Tsuyoshi$4edt$01297612
702   $aShimo$b Tsuyoshi$4oth
906   $aBOOK
912   $a9910557628803321
996   $aHedgehog Signaling in Organogenesis and Tumor Microenvironment$93024614
997   $aUNINA