LEADER 03147nam  2200745z- 450 
001 9910557615103321
005 20220321
035   $a(CKB)5400000000045251
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/79602
035   $a(oapen)doab79602
035   $a(EXLCZ)995400000000045251
100   $a20202203d2022      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aMonoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0
210   $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022
215   $a1 online resource (112 p.)
311 08$a3-0365-3165-3 
311 08$a3-0365-3164-5 
330   $aMonoclonal antibodies (mAbs) are among the most specialised molecules for the recognition and capture of specific analytes. Hundreds of thousands of mAbs have been generated for a large number of different antigens with increasing affinity and specificity and are available for the most diverse purposes. Many of them have been validated as irreplaceable agents for diagnosis and therapy or as unique reagents for research. Others have been developed using emerging technologies that avoid the need for animal immunisation. This short book strives to gather the perspective view of the various contributing authors and to survey the new strategic assets adopted to generate novel monoclonal antibodies or surrogates, such as Fab, Fab2, ScFv and nanobodies, which have an increasing impact in biomedicine as therapeutic or diagnostic assets in various diseases.
606   $aBiology, life sciences$2bicssc
606   $aResearch & information: general$2bicssc
610   $aantibody
610   $aatherosclerosis
610   $abio-layer interferometry
610   $aC. auris
610   $acandidiasis
610   $acell wall
610   $acell-based panning
610   $acompetitive ELISA
610   $aepitope identification
610   $aexcipient
610   $aFGFR3-specific antibody
610   $afoot-and-mouth disease virus
610   $afree radical
610   $ahuman antibody
610   $amAb
610   $amagnetic resonance imaging
610   $amonoclonal antibodies
610   $amonoclonal antibody
610   $amultidrug resistance
610   $anano-emulsion
610   $aoxidation
610   $apassive immunization
610   $aphage display
610   $aPRAME
610   $aprotein aggregation
610   $asemi-automated cell panning
610   $astealth
610   $atype A
610   $atype O
610   $auniversal antibodies
615  7$aBiology, life sciences
615  7$aResearch & information: general
700   $aRuvo$b Menotti$4edt$01292387
702   $aSandomenico$b Annamaria$4edt
702   $aRuvo$b Menotti$4oth
702   $aSandomenico$b Annamaria$4oth
906   $aBOOK
912   $a9910557615103321
996   $aMonoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0$93022242
997   $aUNINA