LEADER 03130nam 2200733z- 450 001 9910557615103321 005 20231214133413.0 035 $a(CKB)5400000000045251 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/79602 035 $a(EXLCZ)995400000000045251 100 $a20202203d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMonoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 electronic resource (112 p.) 311 $a3-0365-3165-3 311 $a3-0365-3164-5 330 $aMonoclonal antibodies (mAbs) are among the most specialised molecules for the recognition and capture of specific analytes. Hundreds of thousands of mAbs have been generated for a large number of different antigens with increasing affinity and specificity and are available for the most diverse purposes. Many of them have been validated as irreplaceable agents for diagnosis and therapy or as unique reagents for research. Others have been developed using emerging technologies that avoid the need for animal immunisation. This short book strives to gather the perspective view of the various contributing authors and to survey the new strategic assets adopted to generate novel monoclonal antibodies or surrogates, such as Fab, Fab2, ScFv and nanobodies, which have an increasing impact in biomedicine as therapeutic or diagnostic assets in various diseases. 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 610 $aPRAME 610 $amAb 610 $abio-layer interferometry 610 $aepitope identification 610 $amonoclonal antibody 610 $afree radical 610 $aprotein aggregation 610 $aoxidation 610 $aexcipient 610 $afoot-and-mouth disease virus 610 $atype O 610 $atype A 610 $aphage display 610 $aantibody 610 $acompetitive ELISA 610 $aatherosclerosis 610 $anano-emulsion 610 $amagnetic resonance imaging 610 $astealth 610 $ahuman antibody 610 $aC. auris 610 $acandidiasis 610 $amultidrug resistance 610 $amonoclonal antibodies 610 $auniversal antibodies 610 $acell wall 610 $apassive immunization 610 $acell-based panning 610 $asemi-automated cell panning 610 $aFGFR3-specific antibody 615 7$aResearch & information: general 615 7$aBiology, life sciences 700 $aRuvo$b Menotti$4edt$01292387 702 $aSandomenico$b Annamaria$4edt 702 $aRuvo$b Menotti$4oth 702 $aSandomenico$b Annamaria$4oth 906 $aBOOK 912 $a9910557615103321 996 $aMonoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0$93022242 997 $aUNINA