LEADER 03353nam 2200985z- 450 001 9910557610103321 005 20220321 035 $a(CKB)5400000000045301 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/79654 035 $a(oapen)doab79654 035 $a(EXLCZ)995400000000045301 100 $a20202203d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aPharmacogenetics to Avoid Adverse Drug Reactions 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (220 p.) 311 08$a3-0365-3344-3 311 08$a3-0365-3343-5 330 $aAdverse drug reactions are one of the major constraints when using drugs. These adverse reactions can impact healthcare systems as strongly as many prevalent diseases. Identifying DNA variants associated with adverse drug reactions can help personalize medicine and sustain healthcare systems. This book delves into new advances in pharmacogenetics of cardiovascular, cancer, and nervous system drugs. It may be useful for clinicians and patients to understand the basics of pharmacogenetics. 606 $aMedicine$2bicssc 610 $a(es)citalopram 610 $a5-fluorouracil 610 $aacute coronary syndrome 610 $aadverse drug reactions 610 $aadverse events 610 $aallele 610 $aanti-epileptic drugs (AEDS) 610 $aantiepileptics 610 $aantipsychotic agents 610 $aatorvastatin 610 $acapecitabine 610 $acardiology 610 $acardiovascular disease 610 $aclinical implementation 610 $aclopidogrel 610 $acolorectal cancer 610 $acutaneous adverse drug reaction 610 $acutaneous adverse drug reactions (CADRs) 610 $aCYP2C9*3 610 $aCYP450 enzymes 610 $acytochrome P-450 enzyme system 610 $adirect oral anticoagulants 610 $adrug-drug-gene-interaction 610 $adrug-drug-interaction 610 $adrug-gene-interaction 610 $aepistasis 610 $afluoropyrimidine 610 $agenetic polymorphism 610 $agenetic risk factors 610 $agenotype 610 $aguidelines 610 $aHLA 610 $aHLA B 610 $aIndia 610 $an/a 610 $apersonalised medicine 610 $apharmacogenetics 610 $apharmacogenomics 610 $aphenytoin (PHT) 610 $aplatelet reactivity 610 $apolymorphism 610 $aprecision medicine 610 $apsychotic disorders 610 $arandom forest 610 $aSCAR 610 $asingle-nucleotide variants 610 $aSLCO1B1 610 $aSouth India 610 $astatin 610 $athe PharmLines initiative 610 $athymidylate synthase 610 $athymidylate synthase enhancer region 610 $atoxicity 610 $aupstream stimulatory factor 1 615 7$aMedicine 700 $aLo?pez-Ferna?ndez$b Luis A$4edt$01319399 702 $aLo?pez-Ferna?ndez$b Luis A$4oth 906 $aBOOK 912 $a9910557610103321 996 $aPharmacogenetics to Avoid Adverse Drug Reactions$93033877 997 $aUNINA