LEADER 01327nam0-22004091i-450- 001 990003935670403321 005 20080214112643.0 010 $a88-430-2240-7 035 $a000393567 035 $aFED01000393567 035 $a(Aleph)000393567FED01 035 $a000393567 100 $a20030910d2002----km-y0itay50------ba 101 0 $aita 102 $aIT 200 1 $a<>ceti medi nel Mezzogiorno$etransizione e identità$fa cura di Francesco Paolo Cerase$gcon contributi di Emma Corigliano, Paola De Vivo e Gabriella Sforza 210 $aRoma$cCarocci$d2002 215 $a189 p.$ctab., fig.$d22 cm 225 1 $aBiblioteca di testi e studi$iSociologia$v189 320 $aContiene riferimenti bibl. 610 0 $aImpiegati pubblici$aItalia meridionale$aInchieste$a1998 676 $a305.556$v21$zita 702 1$aCerase,$bFrancesco Paolo$f<1941- > 702 1$aCorigliano,$bEmma 702 1$aDe Vivo,$bPaola 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990003935670403321 952 $a305.556 CER 1BIS$b8252$fBFS 952 $a305.556 CER 1$b8253$fBFS 952 $a305.556 CER 1TER$b8291$fBFS 952 $a305.556 CER 1QUA$b8250$fBFS 952 $a14230 CER$b19718$fSES 959 $aBFS 959 $aSES 996 $aCeti medi nel Mezzogiorno$9248073 997 $aUNINA LEADER 04848nam 2201393z- 450 001 9910557609003321 005 20220321 035 $a(CKB)5400000000045312 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/79672 035 $a(oapen)doab79672 035 $a(EXLCZ)995400000000045312 100 $a20202203d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aNew Insights in the Genetics and Genomics of Adrenocortical Tumors and Pheochromocytomas 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (272 p.) 311 08$a3-0365-3358-3 311 08$a3-0365-3357-5 330 $aThis book includes 17 papers published in the Special Issue/Article Collectoin "New Insights in the Genetics and Genomics of adrenocortical tumors and pheochromocytomas" including an editorial, 10 research papers and six review articles. Adrenal tumors represent a hot topic in contemporary endocrine oncology. Significant advancements in the genetics of genomics of these tumors have been made in recent years, and these articles give a useful and comprehensive overview of these issues. Questions regarding molecular pathogenesis, diagnosis (biomarkers) and even treatment are discussed in the papers written by international leaders of the field. Manuscripts are focused on three main topics: i. primary aldosteronism (the most common cause of secondary endocrine hypertension), ii. adrenocortical cancer and iii. pheochromocytoma/paraganglioma, which are the tumors with the highest heritability in humans. The book is edited by Prof. Peter Igaz (Department of Endocrinology, Faculty of Medicine, Semmelweis University). 606 $aMedicine$2bicssc 610 $aadaptive metabolism 610 $aadenoma 610 $aadrenal 610 $aadrenal gland 610 $aadrenalectomy 610 $aadrenocortical 610 $aadrenocortical carcinoma 610 $aadrenocortical tumor 610 $aaldosterone 610 $aaldosterone producing adenoma 610 $aaldosterone-producing adenoma 610 $aALT 610 $aarterial stiffness 610 $aartificial intelligence 610 $aATP2B3 610 $aATRX 610 $abioinformatic clustering 610 $abiomarker 610 $abiomarker prediction 610 $acancer 610 $acirculating 610 $aconn adenoma 610 $adriver mutations 610 $adrug discovery 610 $aendocrine tumor syndrome 610 $aenvironment 610 $aepidemiology 610 $aepigenetics 610 $afatty acid metabolism 610 $aferroptosis 610 $agenetic analysis 610 $agenetic testing 610 $agenetics 610 $agermline 610 $aH295 strains 610 $ahereditary 610 $ahereditary cancer 610 $ahyperaldosteronism 610 $ain silico analysis 610 $aK416-F418delinsN mutation 610 $aKCNJ5 somatic mutation 610 $amachine learning 610 $amalignancy 610 $ametabolic reprogramming 610 $ametabolomics 610 $ametastatic 610 $amicroRNA 610 $amitochondrial complex II 610 $amitotane 610 $amortality 610 $amutations 610 $an/a 610 $aneonatal screening 610 $aneural network 610 $anext generation sequencing 610 $aNext Generation Sequencing 610 $anon-coding RNA 610 $aNOP10 610 $aparaganglioma 610 $aparagangliomas 610 $aphaeochromocytoma 610 $apheochromocytoma 610 $apheochromocytomas 610 $aPPAR? 610 $aPPGL 610 $aprimary aldosteronism 610 $aprognostic biomarker 610 $apropensity score matching 610 $apulse wave velocity 610 $aredox balance pathway 610 $aRNAseq 610 $ascreening 610 $asomatic 610 $asurveillance 610 $asusceptibility genes 610 $atelomeres 610 $aTERT 610 $atherapy 610 $atissue 610 $aTP53 R337H 610 $atranscriptomics 610 $atreatment 610 $atumor microenvironment 610 $atumor suppressor genes 610 $avariants 610 $aVitamin C 610 $azebrafish 610 $a?-oxidation 615 7$aMedicine 700 $aIgaz$b Peter$4edt$01082320 702 $aIgaz$b Peter$4oth 906 $aBOOK 912 $a9910557609003321 996 $aNew Insights in the Genetics and Genomics of Adrenocortical Tumors and Pheochromocytomas$93027446 997 $aUNINA