LEADER 03192nam 2200601Ia 450 001 9910788205903321 005 20230124191406.0 010 $a1-4214-0961-5 035 $a(CKB)3170000000060730 035 $a(EBL)3318707 035 $a(SSID)ssj0000950284 035 $a(PQKBManifestationID)11529069 035 $a(PQKBTitleCode)TC0000950284 035 $a(PQKBWorkID)11003502 035 $a(PQKB)10605239 035 $a(MiAaPQ)EBC3318707 035 $a(OCoLC)857081832 035 $a(MdBmJHUP)muse25411 035 $a(Au-PeEL)EBL3318707 035 $a(CaPaEBR)ebr10729543 035 $a(EXLCZ)993170000000060730 100 $a20121206d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aIsaac Beeckman on matter and motion$b[electronic resource] $emechanical philosophy in the making /$fKlaas van Berkel 210 $aBaltimore $cJohns Hopkins University Press$d2013 215 $a1 online resource (276 p.) 300 $aRevision of the author's thesis under title: Isaac Beeckman (1588-1637) en de mechanisering van het wereldbeeld. 311 $a1-4214-0936-4 320 $aIncludes bibliographical references and index. 327 $a""Cover""; ""Contents""; ""Preface""; ""Introduction""; ""1 The Making of a Natural Philosopher, 1588a???1619""; ""2 Schoolteacher and Craftsman, 1619a???1627""; ""3 Among Patricians and Philosophers, 1627a???1637""; ""4 Principles of Mechanical Philosophy I: Matter""; ""5 Principles of Mechanical Philosophy II: Motion""; ""6 Sources for a Mechanical Philosophy""; ""7 Beeckman and the Scientific Revolution""; ""Notes""; ""Bibliographic Essay""; ""Index""; ""A""; ""B""; ""C""; ""D""; ""E""; ""F""; ""G""; ""H""; ""I""; ""J""; ""K""; ""L""; ""M""; ""N""; ""O""; ""P""; ""Q""; ""R""; ""S""; ""T"" 327 $a""U""""V""; ""W""; ""X""; ""Z"" 330 $a"Historians of science and the philosophy of science find the substance and stance of Isaac Beeckman's thought highly interesting, for it represented an early attempt to develop a comprehensive picture of the world by means of mechanistic theory, that is, forces acting upon one another. Besides possibly influencing Descartes, this view broke away from medieval religious assumptions and belief in occult forces. Berkel teases out Beeckman's evolving approach to nature by means of his extensive journals, explaining the leading concept of "picturability." 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Mtb, the causative agent responsible for TB, continues to afflict millions of people worldwide. Furthermore, one-third of the entire world's population has latent TB. Consequently, there has been a worldwide effort to eradicate and limit the spread of Mtb through the use of antibiotics. However, management of TB is becoming more challenging with the emergence of drug-resistant and multi-drug resistant strains of Mtb. Furthermore, when administered, many of the anti-TB drugs commonly present severe complications and side effects. Novel approaches to enhance the host immune responses to completely eradicate Mtb infection are urgently needed. 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