LEADER 03104nam 2200769z- 450 001 9910557602603321 005 20210501 035 $a(CKB)5400000000045377 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69310 035 $a(oapen)doab69310 035 $a(EXLCZ)995400000000045377 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aHost-Directed Therapies for Tuberculosis 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (120 p.) 311 08$a3-03943-501-9 311 08$a3-03943-502-7 330 $aTB is considered as one of the oldest documented infectious diseases in the world and is believed to be the leading cause of mortality due to a single infectious agent. Mtb, the causative agent responsible for TB, continues to afflict millions of people worldwide. Furthermore, one-third of the entire world's population has latent TB. Consequently, there has been a worldwide effort to eradicate and limit the spread of Mtb through the use of antibiotics. However, management of TB is becoming more challenging with the emergence of drug-resistant and multi-drug resistant strains of Mtb. Furthermore, when administered, many of the anti-TB drugs commonly present severe complications and side effects. Novel approaches to enhance the host immune responses to completely eradicate Mtb infection are urgently needed. This Special Issue will therefore cover most recent advances in the area of host-directed therapies for TB. 606 $aBiology, life sciences$2bicssc 606 $aResearch & information: general$2bicssc 610 $aantioxidants 610 $aantiplatelet 610 $aaspirin 610 $aautophagy 610 $aBCG vaccination 610 $aco-infections 610 $aco-morbidities 610 $acytokines 610 $agene expression 610 $aglutathione 610 $agranulomas 610 $ahost-directed therapies 610 $aimmune exhaustion 610 $aimmune response 610 $aimmune responses 610 $aimmunomodulation 610 $ainflammation 610 $ainvasive procedure 610 $airon supplementation 610 $alatent infection 610 $alung cancer 610 $aM. tb 610 $amisdiagnosis 610 $aMycobacterium tuberculosis 610 $apathology 610 $aPerls' stain 610 $apulmonary 610 $arabbit 610 $aredox imbalance 610 $arevising 610 $asurvival 610 $aTaiwan 610 $atuberculosis 610 $atype 2 diabetes 615 7$aBiology, life sciences 615 7$aResearch & information: general 700 $aVenketaraman$b Vishwanath$4edt$01303388 702 $aVenketaraman$b Vishwanath$4oth 906 $aBOOK 912 $a9910557602603321 996 $aHost-Directed Therapies for Tuberculosis$93026986 997 $aUNINA