LEADER 04256nam 2200889z- 450 001 9910585942903321 005 20220812 035 $a(CKB)5600000000483052 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/91171 035 $a(oapen)doab91171 035 $a(EXLCZ)995600000000483052 100 $a20202208d2022 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aQuantum Cosmology 210 $aBasel$cMDPI - Multidisciplinary Digital Publishing Institute$d2022 215 $a1 online resource (402 p.) 311 08$a3-0365-4726-6 311 08$a3-0365-4725-8 330 $aWithin the second half of the last century, quantum cosmology concretely became one of the main research lines within gravitational theory and cosmology. Substantial progress has been made. Furthermore, quantum cosmology can become a domain that will gradually develop further over the next handful of decades, perhaps assisted by technological developments. Indications for new physics (i.e., beyond the standard model of particle physics or general relativity) could emerge and then the observable universe would surely be seen from quite a new perspective. This motivates bringing quantum cosmology to more research groups and individuals.This Special Issue (SI) aims to provide a wide set of reviews, ranging from foundational issues to (very) recent advancing discussions. Concretely, we want to inspire new work proposing observational tests, providing an aggregated set of contributions, covering several lines, some of which are thoroughly explored, some allowing progress, and others much unexplored. The aim of this SI is motivate new researchers to employ and further develop quantum cosmology over the forthcoming decades. Textbooks and reviews exist on the present subject, and this SI will complementarily assist in offering open access to a set of wide-ranging reviews. Hopefully, this will assist new interested researchers, in having a single open access online volume, with reviews that can help. In particular, this will help in selecting what to explore, what to read in more detail, where to proceed, and what to investigate further within quantum cosmology. 606 $aPhysics$2bicssc 606 $aResearch and information: general$2bicssc 610 $aADM formalism 610 $abackreaction effects 610 $abounce 610 $abounce models 610 $aBrans-Dicke theory 610 $acanonical quantum gravity 610 $aclassical and quantum cosmology 610 $aclocks 610 $acyclic universe 610 $adark energy singularities 610 $ade Broglie-Bohm interpretation 610 $aearly universe cosmology 610 $aentanglement entropy 610 $aexact solutions 610 $aextended theories of gravity 610 $ageneralized uncertainty principles 610 $aHawking radiation 610 $ainstantons 610 $aloop quantum cosmology 610 $amultiverse 610 $an/a 610 $ano-boundary proposal 610 $anoether symmetries 610 $anoncommutativity 610 $aobservations 610 $apolymer quantum mechanics 610 $aquantum cosmology 610 $aquantum fields 610 $aquantum fields in curved spacetime 610 $aquantum geometrodynamics 610 $aquantum gravity 610 $ashape invariant potentials 610 $asingularity and bounce 610 $astring cosmology 610 $asuperspace 610 $asupersymmetric quantum cosmology 610 $asupersymmetric quantum mechanics 610 $asupersymmetry 610 $athird quantisation 610 $atime 610 $auniqueness of the quantization 610 $auniverse-antiuniverse pair 610 $aweyl curvature hypothesis 610 $aWheeler-DeWitt equation 615 7$aPhysics 615 7$aResearch and information: general 700 $aMoniz$b Paulo Vargas$4edt$0515326 702 $aMoniz$b Paulo Vargas$4oth 906 $aBOOK 912 $a9910585942903321 996 $aQuantum Cosmology$93038438 997 $aUNINA LEADER 06882nam 2201981z- 450 001 9910557577203321 005 20210501 035 $a(CKB)5400000000043877 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69023 035 $a(oapen)doab69023 035 $a(EXLCZ)995400000000043877 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMitochondria in Health and Diseases 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (434 p.) 311 08$a3-03936-384-0 311 08$a3-03936-385-9 330 $aMitochondria are subcellular organelles evolved by the endosymbiosis of bacteria with eukaryotic cells. They are the main source of ATP in the cell and engaged in other aspects of cell metabolism and cell function, including the regulation of ion homeostasis, cell growth, redox status, and cell signaling. Due to their central role in cell life and death, mitochondria are also involved in the pathogenesis and progression of human diseases/conditions, including neurodegenerative and cardiovascular disorders, cancer, diabetes, inflammation, and aging. However, despite the increasing number of studies, precise mechanisms whereby mitochondria are involved in the regulation of basic physiological functions, as well as their role in the cell under pathophysiological conditions, remain unknown. A lack of in-depth knowledge of the regulatory mechanisms of mitochondrial metabolism and function, as well as interplay between the factors that transform the organelle from its role in pro-survival to pro-death, have hindered the development of new mitochondria-targeted pharmacological and conditional approaches for the treatment of human diseases. This book highlights the latest achievements in elucidating the role of mitochondria under physiological conditions, in various cell/animal models of human diseases, and in patients. 606 $aMedicine and Nursing$2bicssc 610 $a2-oxoglutarate dehydrogenase 610 $a4-HNE 610 $aadenine nucleotide translocase 610 $aADP/ATP carrier 610 $aaging 610 $aamino acid neurotransmitter 610 $aancient mutation 610 $aantioxidant system 610 $aantioxidants 610 $aapoptosis 610 $aBAX 610 $aBCL-2 610 $aBKCa channels 610 $acardiolipin 610 $acardiomyocytes 610 $acardioprotection 610 $acerebellar amino acid metabolism 610 $acholangiocellular carcinoma 610 $acolon 610 $acomplex I (CI) deficiency 610 $acyclosporin A 610 $acytoskeletal proteins 610 $aDDE 610 $adentate granule cell 610 $adevelopment 610 $adextran 610 $aDRP1 610 $adsRNA 610 $aelectron and confocal microscopy 610 $aelectron tunneling (ET) 610 $aenergy metabolism 610 $aepilepsy 610 $aERK1/2 610 $aETC complexes 610 $afatty acid oxidation 610 $aferritin 610 $agemfibrozil 610 $aGW9662 610 $aH9c2 cardiomyoblasts 610 $ahealthy cells 610 $aheart 610 $ahepatic fibrogenesis 610 $ahepcidin 610 $ahigh-fat diet 610 $ahippocampus 610 $aHtrA2/Omi 610 $ahuman amniotic membrane 610 $ahuman diseases 610 $ahyperforin 610 $ahypoglycemia 610 $ahypoxia 610 $ainflammation 610 $ainnate immunity 610 $ainorganic phosphate 610 $ainterferon response 610 $aintranuclear mitochondria 610 $aion homeostasis 610 $airon overload 610 $aischemia reperfusion injury 610 $aJNK 610 $aKmADP 610 $aLangendorff 610 $aLHON 610 $alife span 610 $alipid droplet 610 $alipid handling 610 $aliver 610 $aLONP1 610 $ametabolome and proteome profiling 610 $amitochondria 610 $amitochondria bioenergetics 610 $amitochondria calcium buffering 610 $amitochondria permeability transition pore 610 $amitochondria: energy metabolism 610 $amitochondrial cell death 610 $amitochondrial connexin 43 610 $amitochondrial dynamics 610 $amitochondrial dysfunction 610 $amitochondrial function 610 $amitochondrial gene expression 610 $amitochondrial homeostasis 610 $amitochondrial interactions 610 $amitochondrial permeability transition pores 610 $amitochondrial UCP2 610 $amorphology 610 $amtDNA 610 $amtDNA transcription 610 $amtRNA 610 $amuscle aging 610 $amyocardial 610 $aneuron death 610 $aneuroprotection 610 $aoxidative phosphorylation 610 $aoxidative stress 610 $aperilipin 5 610 $aphysical performance 610 $apilocarpine 610 $apioglitazone 610 $aPKA 610 $aplectin 610 $apost-transcriptional mtRNA processing 610 $apotassium channel 610 $apravastatin 610 $aprotein phosphatases 610 $apyruvate dehydrogenase 610 $apyruvate dehydrogenase kinase 610 $areactive oxygen species 610 $areactive oxygen species (ROS) 610 $areactive oxygen species stress 610 $aredox state 610 $aregeneration 610 $arespirasome assembly 610 $arespiratory supercomplexes 610 $aROS 610 $arosiglitazone 610 $aseizure 610 $aSiberian population 610 $asignaling 610 $asignaling pathways 610 $asiRNA 610 $asodium dichloroacetate 610 $aspecific genetic background 610 $atelomerase activity 610 $atelomere length 610 $atensile strength 610 $atransferrin 610 $atricarboxylic acid cycle 610 $atubulin beta 610 $aTUNEL 610 $aTZD 610 $auncoupling 610 $auncoupling protein 610 $aZIP 615 7$aMedicine and Nursing 700 $aJavadov$b Sabzali$4edt$01280541 702 $aKozlov$b Andrey V$4edt 702 $aCamara$b Amadou K.S$4edt 702 $aJavadov$b Sabzali$4oth 702 $aKozlov$b Andrey V$4oth 702 $aCamara$b Amadou K.S$4oth 906 $aBOOK 912 $a9910557577203321 996 $aMitochondria in Health and Diseases$93017189 997 $aUNINA