LEADER 03482nam 2200973z- 450 001 9910557552303321 005 20210501 035 $a(CKB)5400000000044083 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/68386 035 $a(oapen)doab68386 035 $a(EXLCZ)995400000000044083 100 $a20202105d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aCocrystal Applications in Drug Delivery 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 online resource (172 p.) 311 08$a3-03943-983-9 311 08$a3-03943-984-7 330 $aIn 2015, the first pharmaceutical cocrystal was approved by the FDA. Since then, the number of cocrystals on the market and in the development pipeline has been slowly but steadily growing. It is now well established that cocrystals are a versatile new approach to oral drug formulation. This Reprint Book is a collection of articles that show the utility of pharmaceutical cocrystals and various aspects of cocrystal research: ? Cocrystals as a strategy to modify the physicochemical properties of a drug such as dissolution behaviour, tabletability, and melting point; ? Development of new coformers; ? Screening studies for multiple cocrystal forms; ? Cocrystals in nano-sized drug delivery. 606 $aResearch & information: general$2bicssc 610 $abarbituric acid 610 $acocrystal 610 $acocrystals 610 $acompaction 610 $acrystal engineering 610 $acrystal structure 610 $acrystallization inhibitors 610 $adesign of experiments 610 $adiclofenac sodium 610 $adissolution 610 $adissolution behavior 610 $adissolution rate 610 $adrug-polymer interactions 610 $aformulation 610 $aHIV/AIDS 610 $aimidazole N-oxides 610 $ainterparticulate bonding area 610 $ainterparticulate bonding strength 610 $aitraconazole 610 $aL-proline 610 $alamivudine 610 $amechanochemistry 610 $amonohydrate 610 $amulticomponent crystal 610 $amulticomponent crystals 610 $an/a 610 $anano co-crystals 610 $ananoindentation 610 $anefiracetam 610 $anitazoxanide 610 $aparticle size 610 $apharmaceutical cocrystals 610 $apolydispersity index 610 $aQuality by Design 610 $asalt cocrystal 610 $aslip plane 610 $asolid state 610 $asolid state NMR 610 $asolid-state 610 $asolubility 610 $asonochemistry 610 $astability 610 $asupersaturated formulations 610 $asurface topology 610 $atabletability 610 $aterephthalic acid 610 $atetrahydrate 610 $athermal analysis 610 $athiobarbituric acid 610 $awettability 610 $aX-ray Diffraction 610 $azeta potential 610 $azidovudine 615 7$aResearch & information: general 700 $aErxleben$b Andrea$4edt$01290197 702 $aErxleben$b Andrea$4oth 906 $aBOOK 912 $a9910557552303321 996 $aCocrystal Applications in Drug Delivery$93021414 997 $aUNINA