LEADER 04133nam 2201177z- 450 001 9910557525903321 005 20210501 035 $a(CKB)5400000000044319 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69086 035 $a(oapen)doab69086 035 $a(EXLCZ)995400000000044319 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aVirus-Like Particle Vaccines 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (262 p.) 311 08$a3-03943-074-2 311 08$a3-03943-075-0 330 $aThe structure, uniformity, stability, and functions of virus-like particles (VLPs) have encouraged scientists to utilize them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they induce. The innate immune cells and molecules recognize and interact with VLPs on the basis of two major characteristics: size and surface geometry. VLP-based vaccines against hepatitis B, human papilloma, malaria, and hepatitis E have been developed and are available in many countries around the world. Given the inherent immunogenicity of VLPs, they render themselves ideal for the development of new vaccines against infectious diseases as well as noncommunicable diseases, such as chronic inflammation or cancer. This Special Issue is designed to provide an up-to-date view of the latest progress in the development of VLP-based prophylactic and therapeutic vaccines and technologies for their generation. 606 $aHumanities$2bicssc 606 $aSocial interaction$2bicssc 610 $aantibodies 610 $aantibody titers 610 $aantigen 610 $aantigen display 610 $aantigenic analysis 610 $aavian flu 610 $ablocking antibodies 610 $acancer 610 $acapsid 610 $acat allergy 610 $across-reactivity 610 $acryo-TEM 610 $acytomegalovirus 610 $aepitope 610 $aepitope characterization 610 $aFel d 1 610 $aflow virometry 610 $agenotype 610 $aH7N9 610 $aHCMV 610 $ahepatitis B virus 610 $ahepatitis E vaccine 610 $ahorse 610 $aHPVs 610 $aHypoCat? 610 $aIAV 610 $aIL-13 610 $aimmune response 610 $aimmunotherapy 610 $ainfluenza A(H1N1)pdm09 610 $ainterleukin-13 610 $along-lived plasma cells 610 $amice 610 $aminor capsid protein (L2) 610 $amultivalency 610 $an/a 610 $ananoparticle 610 $anorovirus 610 $aNTA 610 $aoriginal antigenic sin (OAS) 610 $apandemic influenza A 610 $aplant virus 610 $aplatform 610 $apre-existing immunity 610 $apregnant women 610 $apurified IgG 610 $aSEM 610 $aserological evaluation 610 $aSRFM 610 $asub-viral particle 610 $aSudan virus 610 $asurface (envelope) antigen 610 $aTfh cells 610 $avaccination 610 $avaccine 610 $avaccine platform 610 $avaccines 610 $aviral quantification 610 $avirion-like epitopes 610 $avirus-like 610 $avirus-like particle 610 $avirus-like particles 610 $avirus-like particles (VLPs) 610 $aVLP 610 $aVLP vaccine 610 $awell-characterized vaccines 615 7$aHumanities 615 7$aSocial interaction 700 $aBachmann$b Martin F$4edt$01322916 702 $aVogel$b Monique$4edt 702 $aBachmann$b Martin F$4oth 702 $aVogel$b Monique$4oth 906 $aBOOK 912 $a9910557525903321 996 $aVirus-Like Particle Vaccines$93035261 997 $aUNINA