LEADER 04096nam 2201153z- 450 001 9910557525903321 005 20231214133353.0 035 $a(CKB)5400000000044319 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69086 035 $a(EXLCZ)995400000000044319 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aVirus-Like Particle Vaccines 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 electronic resource (262 p.) 311 $a3-03943-074-2 311 $a3-03943-075-0 330 $aThe structure, uniformity, stability, and functions of virus-like particles (VLPs) have encouraged scientists to utilize them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they induce. The innate immune cells and molecules recognize and interact with VLPs on the basis of two major characteristics: size and surface geometry. VLP-based vaccines against hepatitis B, human papilloma, malaria, and hepatitis E have been developed and are available in many countries around the world. Given the inherent immunogenicity of VLPs, they render themselves ideal for the development of new vaccines against infectious diseases as well as noncommunicable diseases, such as chronic inflammation or cancer. This Special Issue is designed to provide an up-to-date view of the latest progress in the development of VLP-based prophylactic and therapeutic vaccines and technologies for their generation. 606 $aHumanities$2bicssc 606 $aSocial interaction$2bicssc 610 $avirus-like particle 610 $ainfluenza A(H1N1)pdm09 610 $avaccination 610 $apregnant women 610 $aantibody titers 610 $anorovirus 610 $aVLP 610 $avaccine 610 $agenotype 610 $apre-existing immunity 610 $across-reactivity 610 $ablocking antibodies 610 $aoriginal antigenic sin (OAS) 610 $aHPVs 610 $avaccines 610 $avirus-like particles (VLPs) 610 $aminor capsid protein (L2) 610 $aHCMV 610 $acytomegalovirus 610 $ananoparticle 610 $aimmune response 610 $aSudan virus 610 $amice 610 $ahorse 610 $apurified IgG 610 $along-lived plasma cells 610 $aantibodies 610 $amultivalency 610 $avirus-like particles 610 $aantigenic analysis 610 $aepitope characterization 610 $ahepatitis E vaccine 610 $aserological evaluation 610 $avirion-like epitopes 610 $awell-characterized vaccines 610 $ahepatitis B virus 610 $asurface (envelope) antigen 610 $asub-viral particle 610 $acapsid 610 $aantigen display 610 $aplatform 610 $aviral quantification 610 $aNTA 610 $aflow virometry 610 $aSRFM 610 $acryo-TEM 610 $aSEM 610 $aplant virus 610 $avirus-like 610 $avaccine platform 610 $aepitope 610 $aantigen 610 $acat allergy 610 $aFel d 1 610 $aHypoCat? 610 $aIL-13 610 $ainterleukin-13 610 $aTfh cells 610 $acancer 610 $aimmunotherapy 610 $aH7N9 610 $apandemic influenza A 610 $aavian flu 610 $aIAV 610 $aVLP vaccine 615 7$aHumanities 615 7$aSocial interaction 700 $aBachmann$b Martin F$4edt$01322916 702 $aVogel$b Monique$4edt 702 $aBachmann$b Martin F$4oth 702 $aVogel$b Monique$4oth 906 $aBOOK 912 $a9910557525903321 996 $aVirus-Like Particle Vaccines$93035261 997 $aUNINA