LEADER 01771nam 2200421z- 450 001 9910557519303321 005 20231214133031.0 035 $a(CKB)5400000000044386 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/73435 035 $a(EXLCZ)995400000000044386 100 $a20202111d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aImmunoregulatory Mechanisms of Interferon 210 $cFrontiers Media SA$d2020 215 $a1 electronic resource (362 p.) 311 $a2-88963-280-6 330 $aInterferons (IFN) belong to the family of cytokines and have been described first in the late 1950s as an inhibitory factor of viral replication. Since then, the impact of interferon has been greatly expanded and its function comprises a role not only in different types of infection, cancer and autoimmunity but importantly also in immunehomeostasis. IFN have important anti-viral effects but it is becoming more and more evident that they are true immunomodulators and have an important impact on the development and maintenance of innate and adaptive immunity. 606 $aMedicine$2bicssc 606 $aImmunology$2bicssc 610 $ainterferons 610 $aIFN 610 $aimmunehomeostasis 610 $aautoimmunity 610 $ammunomodulators 615 7$aMedicine 615 7$aImmunology 700 $aHermann Fritz$b Jorg$4edt$01323415 702 $aDuerr$b Claudia U$4edt 702 $aHermann Fritz$b Jorg$4oth 702 $aDuerr$b Claudia U$4oth 906 $aBOOK 912 $a9910557519303321 996 $aImmunoregulatory Mechanisms of Interferon$93035524 997 $aUNINA