LEADER 01227nam 2200397 450 001 990000744330203316 010 $a3-11-004150-2 035 $a0074433 035 $aUSA010074433 035 $a(ALEPH)000074433USA01 035 $a0074433 100 $a20011115d1983----km-y0itay0103----ba 101 $aeng 102 $aDE 102 $aUS 105 $a||||||||001yy 200 1 $aHolomorphic functions of several variables$ean introduction to fundamental theory$fLudger Kaup, Burchard Kaup$gwith assistance of Gottfried Barthel$gtranslated by Michael Bridgland 210 $aBerlin$aNew York$cW. de Gruyter$d1983 215 $aXIII, 349 p$d24 cm 410 $12001 606 0 $aFunzioni olomorfe 676 $a515.9 700 1$aKAUP,$bLudger$0102741 701 1$aKAUP,$bBurchard$0102742 702 1$aBARTHEL,$bGottfried 702 1$aBRIDGLAND,$bMichael 801 0$aIT$bsalbc$gISBD 912 $a990000744330203316 951 $a515.9 KAU$b13040$c515.9 959 $aBK 969 $aTEC 979 $aPATTY$b90$c20011115$lUSA01$h1038 979 $c20020403$lUSA01$h1722 979 $aPATRY$b90$c20040406$lUSA01$h1651 996 $aHolomorphic functions of several variables$9963627 997 $aUNISA LEADER 03974nam 2200937z- 450 001 9910557484703321 005 20210501 035 $a(CKB)5400000000042985 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69300 035 $a(oapen)doab69300 035 $a(EXLCZ)995400000000042985 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aGenomics and Models of Nerve Sheath Tumors 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (172 p.) 311 08$a3-03943-489-6 311 08$a3-03943-490-X 330 $aNerve sheath tumors can be a significant cause of morbidity for many patients. These include benign tumors such as schwannomas, diffuse and plexiform neurofibromas, and atypical neurofibromas, as well as the aggressive soft tissue sarcoma known as the malignant peripheral nerve sheath tumor (MPNST). Nerve sheath tumors occur sporadically and in the context of the clinical neuro-genetic tumor predisposition syndromes neurofibromatosis type 1 (NF1) and type 2 (NF2). Historically, the mainstay of treatment for nerve sheath tumors has been surgery. However, for both benign and malignant nerve sheath tumors, there is a high recurrence rate, highlighting the pressing need for novel therapies. As we have entered the genomic era, the hope is that an improved understanding of the genetics, and therefore the biology, of these tumors will ultimately lead to therapies that result in better outcomes. In this Special Issue, we include both review articles and original research related to the genomic understanding and modeling of schwannomas, plexiform and diffuse neurofibromas, atypical neurofibromas, and malignant peripheral nerve sheath tumors as well as genomic methods?being developed and applied to advance our?understanding of?these tumors. 606 $aMedicine and Nursing$2bicssc 610 $acancer 610 $acapmatinib 610 $achemoprevention 610 $aclinical genetics 610 $aCOX-2 inhibitor 610 $aCRISPR/Cas9 610 $adoxorubicin 610 $agenetically engineered mouse models 610 $agenomics 610 $aheterogeneity 610 $akinase 610 $akinome adaptation 610 $akinome reprogramming 610 $alatent variables 610 $amachine learning 610 $amalignancy 610 $amalignant peripheral nerve sheath tumor 610 $amalignant peripheral nerve sheath tumors 610 $amebendazole (MBZ) 610 $aMEK 610 $aMET 610 $ametaVIPER 610 $amouse models 610 $aMPNST 610 $anerve sheath tumor 610 $anerve sheath tumors 610 $aneurofibromatosis 610 $aneurofibromatosis 1 (NF1) 610 $aneurofibromatosis type 1 610 $aneurofibromatosis type 1 syndrome 610 $aneurofibromin 1 610 $anext generation sequencing 610 $aNF1 610 $apathology 610 $aplexiform neurofibromas 610 $apolycomb repressive complex 610 $aPRC2 610 $arandom forest 610 $asarcoma 610 $aSchwann cells 610 $asupervised learning 610 $atram 610 $atransfer learning 610 $atumor deconvolution 610 $atumor evolution 610 $atumor microenvironment 615 7$aMedicine and Nursing 700 $aHirbe$b Angela C$4edt$01312695 702 $aPratilas$b Christine A$4edt 702 $aDodd$b Rebecca D$4edt 702 $aHirbe$b Angela C$4oth 702 $aPratilas$b Christine A$4oth 702 $aDodd$b Rebecca D$4oth 906 $aBOOK 912 $a9910557484703321 996 $aGenomics and Models of Nerve Sheath Tumors$93030922 997 $aUNINA