LEADER 07295nam 2202125z- 450 001 9910557476303321 005 20231214133155.0 035 $a(CKB)5400000000043034 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69198 035 $a(EXLCZ)995400000000043034 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aRole of Natural Bioactive Compounds in the Rise and Fall of Cancers$eVolume 2 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 electronic resource (318 p.) 311 $a3-03943-292-3 311 $a3-03943-293-1 330 $aRecent years have seen the idea of a close association between nutrition and the modulation of cancer development/progression reinforced. An increasing amount of experimental and epidemiological evidence has been produced supporting the concept that many different bioactive components of food (e.g. polyphenols, mono- and polyunsaturated fatty acids, methyl-group donors, etc.) may be implicated in either the promotion of or the protection against carcinogenesis. At the cellular level, such compounds can have an impact on different but sometimes intertwined processes, such as growth and differentiation, DNA repair, programmed cell death, and oxidative stress. In addition, compelling evidence is starting to build up of the existence of primary epigenetic targets of dietary compounds, such as oncogenic/oncosuppressor miRNAs or DNA-modifying enzymes, which in turn impair gene expression and function. Since there is a growing interest in the study of the biochemical and molecular role played by food components and its impact on cellular processes and/or gene expressions directed towards the fine-tuning of cancer phenotypes, in this Special Issue researchers contributed with either research or review articles presenting the latest findings on the intracellular pathways and mechanisms affected by natural bioactive dietary molecules. 517 $aRole of Natural Bioactive Compounds in the Rise and Fall of Cancers 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 610 $aberberine 610 $asignaling pathways 610 $aoncogenic cascades 610 $aTRAIL 610 $amicroRNAs 610 $acancer therapy 610 $acolon cancer cells 610 $aethanol 610 $aNrf2 610 $aHO-1 610 $aER stress 610 $aautophagy 610 $aMMPs 610 $aformononetin 610 $acancer 610 $apreclinical models 610 $acell signaling 610 $aangiogenesis 610 $anobiletin 610 $acolorectal cancer 610 $achemoprevention 610 $abioactivities 610 $aexperimental therapeutics 610 $aHDAC 610 $amultiple myeloma 610 $aoleacein 610 $abreast cancer 610 $apersistent organic pollutants 610 $abreast cancer risk 610 $abreast cancer prognostic 610 $asystematic review 610 $acarrageenan 610 $ainvasion 610 $ametastasis 610 $aRacGAP1 610 $aradiotherapy 610 $amarine sponge 610 $anatural product 610 $aanticancer drug 610 $aoral cancer inhibition 610 $aphytochemicals 610 $asmall organic agents 610 $aPiper eriopodon, alkenylphenols 610 $ahuman cancer cells 610 $acell death 610 $aapoptosis 610 $acaspase-independent cell death 610 $aXIAP antagonists 610 $aXIAP-BIR3 domain 610 $aCalocedrus formosana 610 $alung cancer 610 $ayatein 610 $acell-cycle arrest 610 $axenograft 610 $aisorhamnetin 610 $aG2/M arrest 610 $aROS 610 $aAMPK 610 $apancreatic cancer 610 $aepigallocatechin-3-gallate (EGCG) 610 $agemcitabine 610 $aglycolysis 610 $aphosphofructokinase 610 $anatural polyphenols 610 $aanticancer activities 610 $amolecular mechanisms 610 $aStreptomyces 610 $amangrove 610 $aanti-proliferative 610 $acolon cancer 610 $aepithelial mesenchymal transition 610 $ainflammation 610 $amalignant cancer 610 $anatural anti-inflammatory compounds 610 $apro-resolving lipids 610 $aanticancer drugs 610 $aflavonoids 610 $anatural compounds 610 $aXenopus laevis 610 $aAOM/DSS model 610 $amelanoma cells 610 $anicotine 610 $a?9-nAChR 610 $aPD-L1 610 $aSTAT3 610 $agigantol 610 $aAKT 610 $aJAK/STAT 610 $acancer stem cell 610 $atumor maintenance 610 $atumor density 610 $aproteomics 610 $ahonokiol 610 $aanticancer 610 $amechanism 610 $asignalling pathway 610 $auterine sarcoma 610 $afucoidan 610 $aisobolography 610 $acolchicine alkaloid 610 $amesoporous silica nanoparticles 610 $atargeted delivery system 610 $aPD-1 immune checkpoint inhibitor and cancer immunotherapy 610 $aglucose transport 610 $adrugs 610 $ainnate immunity 610 $a?-glucans 610 $anutrition 610 $aimmunotherapy 610 $aestrogen 610 $aestrogen receptor alpha 610 $apolyphenols 610 $adaidzein 610 $adaidzein metabolites 610 $apaclitaxel 610 $abreast cancer cells 610 $aobesity 610 $arenin-angiotensin system 610 $aeicosapentaenoic acid 610 $aadipocyte inflammation 610 $aolive leaf extract 610 $aoleuropein 610 $aSeahorse analysis 610 $acancer metabolism 610 $aglycolytic markers 610 $aMalva pseudolavatera Webb & 610 $aBerthel. 610 $aacute myeloid leukemia 610 $areactive oxygen species 610 $abrain cancer 610 $agliomas 610 $aschwannomas 610 $amalignant tumors of the peripheral nerve sheath (MPNST) 610 $aneurofibromas 610 $abioavailability 610 $ananoparticle-based delivery systems 610 $anatural bioactive compound 610 $agallic acid 610 $aEGFR signaling 610 $ap53 610 $aEGCG 610 $anon-coding RNAs 610 $aanti-cancer drug 610 $aNSCLC 610 $aEGFR TKI 610 $aFASN inhibitors 610 $aresistance 615 7$aResearch & information: general 615 7$aBiology, life sciences 700 $aLuparello$b Claudio$4edt$01291782 702 $aLuparello$b Claudio$4oth 906 $aBOOK 912 $a9910557476303321 996 $aRole of Natural Bioactive Compounds in the Rise and Fall of Cancers$93021915 997 $aUNINA