LEADER 04256nam 2200973z- 450 001 9910557463103321 005 20231214132848.0 035 $a(CKB)5400000000043168 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/68337 035 $a(EXLCZ)995400000000043168 100 $a20202105d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMathematical Modelling in Biomedicine 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 electronic resource (224 p.) 311 $a3-03943-493-4 311 $a3-03943-494-2 330 $aMathematical modelling in biomedicine is a rapidly developing scientific discipline at the intersection of medicine, biology, mathematics, physics, and computer science. Its progress is stimulated by fundamental scientific questions and by the applications to public health. This book represents a collection of papers devoted to mathematical modelling of various physiological problems in normal and pathological conditions. It covers a broad range of topics including cardiovascular system and diseases, heart and brain modelling, tumor growth, viral infections, and immune response. Computational models of blood circulation are used to study the influence of heart arrhythmias on coronary blood flow and on operating modes for left-ventricle-assisted devices. Wave propagation in the cardiac tissue is investigated in order to show the influence of tissue heterogeneity and fibrosis. The models of tumor growth are used to determine optimal protocols of antiangiogenic and radiotherapy. The models of viral hepatitis kinetics are considered for the parameter identification, and the evolution of viral quasi-species is investigated. The book presents the state-of-the-art in mathematical modelling in biomedicine and opens new perspectives in this passionate field of research. 606 $aResearch & information: general$2bicssc 606 $aMathematics & science$2bicssc 610 $avirus density distribution 610 $agenotype 610 $avirus infection 610 $aimmune response 610 $aresistance to treatment 610 $anonlocal interaction 610 $aquasi-species diversification 610 $amathematical oncology 610 $aspatially distributed modeling 610 $areaction-diffusion-convection equations 610 $acomputer experiment 610 $aspiral wave 610 $aheterogeneity 610 $aheart modeling 610 $amyocardium 610 $aleft ventricle 610 $aneural field model 610 $aintegro-differential equation 610 $awaves 610 $abrain stimulation 610 $amathematical modeling 610 $acardiac mechanics 610 $amultiscale simulation 610 $acardiomyopathies 610 $aleft ventricle remodeling 610 $aspatially-distributed modeling 610 $agradient descent 610 $a1D haemodynamics 610 $asystole variations 610 $acoronary circulation 610 $acardiac pacing 610 $atachycardia 610 $abradycardia 610 $ainterventricular asynchrony 610 $along QT syndrome 610 $apremature ventricular contraction 610 $arotary blood pump 610 $alumped heart model 610 $acardiac fibrosis 610 $aexcitable media 610 $awave break 610 $aelongated obstacle 610 $alymph flow 610 $amathematical modelling 610 $alymphatic vessels 610 $alymph nodes 610 $aparameter estimation 610 $aconstrained optimization 610 $aderivative free optimization 610 $amultiscale models 610 $adifferential equations 610 $aviral hepatitis 615 7$aResearch & information: general 615 7$aMathematics & science 700 $aVolpert$b Vitaly$4edt$060607 702 $aVolpert$b Vitaly$4oth 906 $aBOOK 912 $a9910557463103321 996 $aMathematical Modelling in Biomedicine$93026549 997 $aUNINA