LEADER 02363nam  2200373z- 450 
001 9910557460503321
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010   $a3-03897-571-0
035   $a(CKB)4100000010106508
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/47256
035   $a(EXLCZ)994100000010106508
100   $a20202102d2019      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aExtracellular Matrix in Development and Disease
210   $cMDPI - Multidisciplinary Digital Publishing Institute$d2019
215   $a1 electronic resource (356 p.)
311   $a3-03897-570-2 
330   $aThe extracellular matrix in development and disease deals with the molecular and cellular aspects of development and disease. Cells exist in three-dimensional scaffolding called the extracellular matrix. The matrix holds together the millions of cells that make up our blood vessels, organs, skin, and all tissues of the body. The matrix serves as a reservoir of signaling molecules as well. In bacterial cultures, biofilms form as an extracellular matrix and play essential roles in disease and drug resistance. Topics such as matrix structure and function, cell attachment and cell surface proteins mediating cell-matrix interactions, synthesis, regulation, composition, structure, assembly, remodeling, and function of the matrix are included. A common thread uniting the topics is the essential nature that the matrix plays in normal development and pathophysiology. Providing new knowledge will lead us to improved diagnostics, the preventions of disease progression, and therapeutic strategies for the repair and regeneration of tissues. Topics such as the extracellular matrix in hereditary diseases, reproduction, cancer, muscle, and tissue engineering applications, and diverse roles for integrins, are included in this collection.
610   $atissue engineering
610   $aembryonic development
610   $abiofilm
610   $acollagen
610   $afibrosis
610   $aextracellular matrix
610   $adegenerative disease
700   $aJulia Thom Oxford (Ed.)$4auth$01294216
906   $aBOOK
912   $a9910557460503321
996   $aExtracellular Matrix in Development and Disease$93023053
997   $aUNINA