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010   $a3-03842-715-2
035   $a(CKB)5400000000000170
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/55526
035   $a(EXLCZ)995400000000000170
100   $a20202102d2018      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aOvarian Cancer Screening
210   $cMDPI - Multidisciplinary Digital Publishing Institute$d2018
215   $a1 electronic resource (VI, 124 p.)
311   $a3-03842-716-0 
330   $aPresented here are scientific reports which add considerable information to the area of early stage ovarian cancer detection and the application of this detection to ovarian cancer screening. In this volume, the following presentations are made: 1) The performance of different ultrasound-based International Ovarian Tumor Analysis (IOTA) strategies is analyzed to discriminate between early stage ovarian malignancy and benign abnormalities of the ovary. 2) Since oophorectomy confers protection against ovarian cancer, when adjustment for oophorectomy was made, rates of ovarian cancer were substantially higher. 3) The frequency of symptoms relevant to ovarian cancer was found to be more than two-hundred times higher than the occurrence of ovarian cancer and it was found that 80.1% of women expressed confidence in the symptoms they reported. 4) Complications resulting from surgery performed in the Kentucky Ovarian Cancer Screening Program were infrequent and significantly fewer than reported in the Prostate, Lung, Colorectal and Ovarian Cancer Screening trial. Complications observed were mostly minor (93%) and were more common in cancer versus non-cancer surgery. 5) Arguments in favor of serial ultrasonography as an alternative to immediate surgery are presented and illustrate the benefits of surveillance. 6) Ten critical considerations for ovarian cancer screening are presented in depth, highlighting their important bearing on ovarian screening outcomes and their interpretations. 7) Considerations that have psychological and behavioral impacts on individuals participating in ovarian screening suggest that a ?normal? screening test result can have psychological benefits, including an increased positive effect and beliefs in the efficacy of screening. 8) The efficacy of ovarian cancer screening may be higher in Asia than in Europe and the USA. Additionally, the re-analysis of PLCO screening data, when cancers presenting more than one year after screening are excluded, shows a significant survival benefit in the PLCO screening trial. 9) The effect that ovarian cancer has on patients and their families is examined from the perspective of a first-year resident in Obstetrics and Gynecology. 10) The 50-year history of biomarkers and ultrasound in the context of ovarian cancer indicates the importance of serial application of both biomarkers and ultrasound. Taken together, this volume provides both original data and overviews of ovarian cancer screening studies that enhance the present interpretation of this type of screening.
610   $atreatment
610   $acollateral affectors
610   $acosts
610   $ascreening
610   $aendpoints
610   $atrail design
610   $aovarian cancer
610   $aefficacy
700   $aEdward J. Pavlik (Ed.)$4auth$01278604
906   $aBOOK
912   $a9910557444903321
996   $aOvarian Cancer Screening$93013593
997   $aUNINA