LEADER 05206nam 2201033z- 450 001 9910557419603321 005 20231214132926.0 035 $a(CKB)5400000000043498 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76464 035 $a(EXLCZ)995400000000043498 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMycotoxins Study: Toxicology, Identification and Control 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 electronic resource (165 p.) 311 $a3-0365-1416-3 311 $a3-0365-1415-5 330 $aThis Book of Toxins comprises 11 original contributions and one review. New findings regarding presence of mycotoxins in aromatic and medicinal plants, mango and orange juice, juices, pulps, jams, and beer, from Morocco, Pakistan, and Portugal are reported. In these studies, innovative techniques to study their presence has been developed, including liquid chromatography coupled with time-of-flight mass spectrometry to analyse mycotoxins and conjugated mycotoxins. Novel strategies to detect mycotoxin presence and comparisons the characteristics of a rapid quantitative analysis of different mycotoxins (deoxynivalenol, ochratoxin A, patulin, sterigmatocystin, and zearalenone) are also presented using acetyl- and butyrylcholinesterases and photobacterial strains of luminescent cells. Additionally, toxicological effects of zearalenone metabolites and beauvericin on SH-SY5Y neuronal cells are presented. One important point in the control of mycotoxins is related to decontaminated strategies, and in this sense the efficacy of potentially probiotic fruit-derived Lactobacillus isolates in removing aflatoxin M1 (AFM1) is presented. Other mycotoxin decontaminated techniques included in this book are electron beam irradiation (EBI) and degradation of zearalenone and ochratoxin A using ozone. Finally, a review that summarizes the newly discovered macrocyclic trichothecenes and their bioactivities over the last decade is included.The evaluation of the presence of mycotoxins in different matrices is achieved through different analytical tools (including quantitative or qualitative determinations). Studies of mycotoxin isolation, using chromatographyc equipment coupled to spectrometry detectors (QTrap-MS/MS, MS/MS tandem, QTOF-MS/MS), are the most useful tools to control their presence. All these studies represent key steps in the establishment of the limits of detection, limits of quantification, points of identification, accuracy, reproducibility, and repeatability of different procedures. The maximum permitted or recommended levels for mycotoxins in different matrices are within a wide range (including the levels tolerated by infants and animals). In addition, decontaminated strategies, as well as control and evaluation of exposure, are demanded by authorities and food safety systems. 517 $aMycotoxins Study 606 $aMedicine$2bicssc 610 $apatulin 610 $amango 610 $aorange 610 $afruit-derived products 610 $afood safety 610 $aregulatory limits 610 $achitosan 610 $amycotoxins 610 $adetoxification 610 $aLC-MS/MS 610 $aoptimization 610 $aDestruxins 610 $aBombyx mori 610 $aBmArgRS 610 $aBmLamin-C 610 $aRNA helicase 610 $abinding protein 610 $aozone 610 $aelectron beam irradiation 610 $adegradation 610 $azearalenone 610 $aochratoxin A 610 $aSH-SY5Y cells 610 $azearalenone derivates 610 $abeauvericin 610 $aMTT 610 $aqTOF-MS/MS 610 $abeer 610 $aimmunoaffinity clean-up 610 $aLC-FD 610 $ahuman risk assessment 610 $aEnniatin B1 610 $abiomonitoring 610 $ain vivo 610 $ametabolomics 610 $ahigh resolution mass spectrometry (HRMS) 610 $amacrocyclic trichothecenes 610 $abioactivities 610 $aputative biosynthetic pathway 610 $amacrocycle formation 610 $aentomopathogens 610 $amycoinsecticides 610 $asecondary metabolites 610 $ainsect pathogenesis 610 $aacetamiprid accumulation 610 $aaflatoxin M1 610 $aLactobacillus 610 $aprobiotics 610 $abinding 610 $abioluminescent bacteria 610 $aimmobilized cells 610 $acholinesterase-based analysis 610 $aanalytical characteristics 610 $aenzymatic detoxification 610 $aco-occurrence 610 $aQ-TOF-LC/MS 610 $aexposure 610 $aMorocco 615 7$aMedicine 700 $aJuan Garci?a$b Cristina$4edt$01295538 702 $aJuan Garci?a$b Cristina$4oth 906 $aBOOK 912 $a9910557419603321 996 $aMycotoxins Study: Toxicology, Identification and Control$93023593 997 $aUNINA