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Mikkelsen 210 1$aBerkeley, CA :$cUniversity of California Press,$d[1997] 210 4$dİ1997 215 $a1 online resource (289 p.) 300 $aDescription based upon print version of record. 311 0 $a0-520-21248-7 327 $tFront matter --$tContents --$tList of Tables and Maps --$tForeword --$tPreface (1997) --$tPreface (1990) --$tAcknowledgments --$tIntroduction --$t1. Town in Turmoil: History and Significance of the Woburn Cluster --$t2. The Formation of an Organized Community --$t3. The Sickness Caused by "Corporate America": Effects of the Woburn Cluster --$t4. Taking Control: Popular Epidemiology --$t5. Making It Safe: Securing Future Health --$tNotes --$tBibliography --$tIndex 330 $aToxic waste, contaminated water, cancer clusters-these phrases suggest deception and irresponsibility. But more significantly, they are watchwords for a growing struggle between communities, corporations, and government. In No Safe Place, sociologists, public policy professionals, and activists will learn how residents of Woburn, Massachusetts discovered a childhood leukemia cluster and eventually sued two corporate giants. Their story gives rise to questions important to any concerned citizen: What kind of government regulatory action can control pollution? Just how effective can the recent upsurge of popular participation in science and technology be? Phil Brown, a medical sociologist, and Edwin Mikkelsen, psychiatric consultant to the plaintiffs, look at the Woburn experience in light of similar cases, such as Love Canal, in order to show that toxic waste contamination reveals fundamental flaws in the corporate, governmental, and scientific spheres. The authors strike a humane, constructive note amidst chilling odds, advocating extensive lay involvement based on the Woburn model of civic action. Finally, they propose a safe policy for toxic wastes and governmental/corporate responsibility. Woburn, the authors predict, will become a code word for environmental struggles. 606 $aHazardous wastes$xEnvironmental aspects$xMassachusetts$xWoburn 606 $aLeukemia$xMassachusetts 606 $aLeukemia in children$xMassachusetts$xWoburn 606 $aLeukemia in children 610 $acancer clusters. 610 $acancer. 610 $acivic action. 610 $aconservation. 610 $acontaminated water. 610 $acontamination. 610 $acorporate responsibility. 610 $acorporations. 610 $adiseases. 610 $aenvironment regulations. 610 $aenvironmental impact. 610 $aflint. 610 $agroundwater. 610 $ahealth policy. 610 $ahealth. 610 $alegal system. 610 $aleukemia. 610 $alitigation. 610 $alove canal. 610 $amassachusetts. 610 $amedicine. 610 $anature. 610 $anonfiction. 610 $apollution. 610 $apopular science. 610 $apublic health. 610 $apublic policy. 610 $asafe water. 610 $ascience. 610 $asustainability. 610 $atoxic waste. 610 $awater politics. 610 $awater rights. 610 $awoburn. 615 0$aHazardous wastes$xEnvironmental aspects$xMassachusetts$xWoburn. 615 0$aLeukemia$xMassachusetts. 615 0$aLeukemia in children$xMassachusetts$xWoburn. 615 0$aLeukemia in children. 676 $a363.72875809744 676 $a618.92 676 $a618.9299419 700 $aBrown$b Phil$4aut$4http://id.loc.gov/vocabulary/relators/aut$01509693 702 $aMikkelsen$b Edwin J.$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bDE-B1597 801 1$bDE-B1597 906 $aBOOK 912 $a9910780012303321 996 $aNo Safe Place$93768233 997 $aUNINA LEADER 03892nam 2200877z- 450 001 9910557390503321 005 20220111 035 $a(CKB)5400000000041993 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/77077 035 $a(oapen)doab77077 035 $a(EXLCZ)995400000000041993 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMultimodality Treatments in Metastatic Gastric Cancer 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 online resource (162 p.) 311 08$a3-0365-2592-0 311 08$a3-0365-2593-9 330 $aGastric cancer represents one of the most frequent and lethal tumors worldwide today, finding itself in the fifth place in incidence and the third in mortality. Surgery remains the only curative treatment for localized tumors, but only 20% of patients are suitable for surgery due to the lack of specific symptoms and the late diagnosis, especially in Western countries. Additionally, even in patients who receive curative treatment, rates of locoregional relapse and distant metastasis remain high. Palliative chemotherapy is the principal treatment in cases of metastatic disease even if the prognosis of patients receiving chemotherapy is still poor. Therefore, a multidisciplinary evaluation is important in order to improve the efficacy of active treatments. In this context, there is an unmet need for a better understanding of genetic alterations and prognostic and predictive factors in order to choose the best tailored therapy for each patient. The aim of this Special Issue is to focus on the results and problems of multimodality treatment in metastatic gastric cancer, the search for prognostic and predictive factors, and the evaluation of novel strategies for individualized treatment. We are inviting relevant original research, systematic reviews, meta-analyses, and short communications covering the above-mentioned topics. 606 $aMedicine$2bicssc 610 $aadvanced gastric cancer 610 $abiomarkers 610 $abody composition 610 $abone flare 610 $aCAR T cell therapy 610 $acfDNA 610 $acirculating tumor cell 610 $aconversion surgery 610 $actDNA 610 $aepithelial-mesenchymal transition 610 $aEpstein Barr Virus 610 $aexome sequencing 610 $aformalin fixed paraffin embedded 610 $agastric cancer 610 $agastro-oesophageal cancer 610 $ahepatectomy 610 $aHER2-inhibition 610 $aimmune checkpoint inhibitors 610 $aimmunotherapy 610 $aliquid biopsy 610 $aliver metastasis 610 $ametastatic 610 $ametastatic gastric cancer 610 $amicrosatellite instability 610 $amutational concordance 610 $an/a 610 $anew drug development 610 $anutritional status 610 $aoutcome 610 $aprecision medicine 610 $apredictive biomarkers 610 $aRANK-L 610 $aresistance to treatment 610 $aresponse monitoring 610 $asarcopenia 610 $astage IV 610 $astage iv gastric cancer 610 $asubcutaneous fat area 610 $atarget therapy 610 $atoxicity 610 $atreatment 610 $atumor mutational burden 610 $avaccines 610 $aVEGFR-inhibition 610 $avisceral fat area 615 7$aMedicine 700 $aPetrillo$b Angelica$4edt$01295530 702 $aPetrillo$b Angelica$4oth 906 $aBOOK 912 $a9910557390503321 996 $aMultimodality Treatments in Metastatic Gastric Cancer$93023583 997 $aUNINA