LEADER 05595nam 2201393z- 450 001 9910557370303321 005 20220111 035 $a(CKB)5400000000042188 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/77079 035 $a(oapen)doab77079 035 $a(EXLCZ)995400000000042188 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aAnticancer Properties of Natural and Derivative Products 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 online resource (312 p.) 311 08$a3-0365-2588-2 311 08$a3-0365-2589-0 330 $aNatural products are bioactive compounds synthesized by terrestrial and marine plants, microorganisms and animals, whose main objective is to prevent them from attacks by predators and/or pathogens. Traditionally since ancient times, different cultures have used these compounds for the prevention and treatment of various human diseases. During the last few years, it has been reported that most of these phytochemicals possess a variety of interesting and significant biological properties, such as analgesic, antiallodynic, antidiabetic, antioxidant, antiparasitic, antimicrobial, antiviral, antiatherogenic, anti-inflammatory, antiproliferative, antitumor and normal growth stimulants, as well as significant cardioprotective and neuroprotective activity. This thematic book aims to collect and disseminate some of the most significant and recent contributions of the use of the natural compounds called phytochemicals, as well as some of their chemical derivatives, for the prevention and treatment of cancer and other accompanying diseases. On the other hand, in recent years, the synthesis of numerous chemical derivatives of these natural compounds has also intensified, with the aim of enhancing their bioactive capacities. Among all these bioactivities, special attention has been paid to its antitumor capacity through the potential modulation of cancer initiation and growth, cell differentiation, apoptosis and autophagy, angiogenesis, and metastatic dissemination. In addition, a considerable number of studies have linked their anticancer effects to their anti-inflammatory and antioxidant activities. 606 $aResearch and information: general$2bicssc 610 $a1,3-dipolar cycloaddition 610 $a3-hydroxy-?-ionone 610 $aactin cytoskeleton 610 $aAdenosma bracteosum 610 $aAKT/PI3K signaling pathway 610 $aanti-cancer 610 $aanti-inflammatory agent 610 $aanti-proliferative activity 610 $aanticancer activity 610 $aanticancer agent 610 $aantioxidant 610 $aantioxidant activity 610 $aantioxidant enzymes 610 $aapoptosis 610 $aautophagy 610 $abetulin glycoconjugates 610 $abetulinic acid 610 $abioactive compounds 610 $abreast cancer 610 $acancer 610 $acaspase-3 610 $aCaveolin-1 610 $acell cycle 610 $acell line 610 $achemoprevention 610 $achemotherapy 610 $aclick chemistry 610 $acomplementary medicine 610 $acytotoxicity 610 $adanthron 610 $aDNA 610 $aDPPH 610 $aElaeagnus angustifolia 610 $aemodin 610 $aEMT 610 $aextract 610 $aGC-MS 610 $agingival fibroblasts 610 $aglioblastoma (GBM) 610 $agrapes 610 $ahepatocellular carcinoma (HCC) 610 $ahuman hepatocarcinoma HepG2 cells 610 $ahypericin 610 $ain vivo 610 $ainteraction 610 $aisolated compounds 610 $alactucopicrin (LCTP) 610 $alung metastases 610 $amaslinic acid 610 $amedicinal mushrooms 610 $amelanoma 610 $ametabolites 610 $amigration activity 610 $aMoringa oleifera 610 $an/a 610 $anatural compounds 610 $anatural extract 610 $anatural photosensitive compounds 610 $anatural product 610 $aNF-?B 610 $aOlea europaea L. 610 $aoleanolic acid 610 $aoral cancer 610 $aoxidative stress 610 $ap62/SQSM1 610 $aphotodynamic therapy 610 $aphotosensitiser 610 $aPogostemon cablin (PPa extract) 610 $aproliferation 610 $aquinizarin 610 $arhodamine B 610 $aROS level 610 $aROS levels 610 $asquamous cell carcinoma 610 $asynergism 610 $atemozolomide (TMZ) 610 $atherapeutic triglyceride 610 $atormentic acid 610 $atotal flavonoid content 610 $atotal phenolic content 610 $atriterpenoic acid 610 $auvaol 610 $awine 610 $axenograft study 615 7$aResearch and information: general 700 $aLupia?n?ez$b Jose? Antonio$4edt$01328632 702 $aPe?rez-Jime?nez$b Amalia$4edt 702 $aRufino-Palomares$b Eva E$4edt 702 $aLupia?n?ez$b Jose? Antonio$4oth 702 $aPe?rez-Jime?nez$b Amalia$4oth 702 $aRufino-Palomares$b Eva E$4oth 906 $aBOOK 912 $a9910557370303321 996 $aAnticancer Properties of Natural and Derivative Products$93038752 997 $aUNINA