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During the last trimester of gestation and for the first 18 months after birth, both DHA and ARA are preferentially deposited within the cerebral cortex at a rapid rate. The mode of action of these two fatty acids and their derivatives at different structural?functional roles, and their levels in the signaling pathways of the brain have been continuously studied. These fatty acids are also involved in various brain developmental processes; however, their mechanistic cross talks are not yet clearly known. Recent data suggest that there may be a need for a balanced proportion of ARA and DHA in infant formula due to their complementary benefits. This review describes the importance of ARA in addition to DHA to support optimal brain development and growth in an infant, and functional roles in the brain. 606 $aMedicine$2bicssc 610 $amaternal supplementation 610 $apregnancy 610 $alactation 610 $adocosahexaenoic acid (DHA) 610 $aneurodevelopment 610 $arandomized controlled trial (RCT) 610 $aIndia 610 $aDHA 610 $abrain 610 $aMFSD2a 610 $aSPM 610 $afetus 610 $aplacenta 610 $ainfant 610 $aneurogenesis 610 $apre-term 610 $adocosahexaenoic acid 610 $asupplementation 610 $aegg yolk 610 $amicroalgae 610 $along chain omega-3 fatty acids 610 $apregnancy outcomes 610 $aanthropometry 610 $abirth weight 610 $abirth length 610 $ahead circumference 610 $aarachidonic acid,20:4n-6 610 $adocosahexaenoic acid,22:6n-3 610 $amaternal diet 610 $acognitive 610 $ainfants 615 7$aMedicine 700 $aDuttaroy$b Asim K$4edt$0963204 702 $aDuttaroy$b Asim K$4oth 906 $aBOOK 912 $a9910557361403321 996 $aMaternal DHA Impact on Child Neurodevelopment$93033305 997 $aUNINA