LEADER 03701nam  2200985z- 450 
001 9910557349303321
005 20220111
035   $a(CKB)5400000000042397
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/77075
035   $a(oapen)doab77075
035   $a(EXLCZ)995400000000042397
100   $a20202201d2021      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aMulti-Omics for the Understanding of Brain Diseases
210   $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021
215   $a1 online resource (204 p.)
311 08$a3-0365-2602-1 
311 08$a3-0365-2603-X 
330   $aOmics technologies such as proteomics, genomics, and metabolomics are widely applied for the identification and characterization of new molecular signatures. However, molecular profiling that makes it possible to understand neurodegenerative diseases has been relatively insufficient. Brain diseases such as neurodegenerative diseases and emotional disorders need integrative understanding which draws on a more reliable hypothesis for pathology, which can be accomplished via in-depth study of molecular information. Recently, multi-omics technologies have been eagerly applied to a diverse range of diseases. As this includes multiple molecular profiling, metadata, and Big Data processing with informatics and computer science, it is possible to provide new macroscopic and microscopic insights in order to better understand diseases. This Special Issue will introduce recent technological advances in multi-omics and the application of omics technology to brain diseases.
606   $aResearch & information: general$2bicssc
610   $a3D culture
610   $aabnormal behavior gene set
610   $aageing
610   $aAlzheimer's disease
610   $abiomarker
610   $abrain
610   $aceramides
610   $achloride adducts
610   $achromosome 22q11.21
610   $aCNV
610   $acopy number variant
610   $aCSF
610   $ade novo mutation
610   $aDGCR8
610   $adifferentially expressed genes
610   $aepigenetics
610   $aepigenome
610   $aflow infusion analysis
610   $agenetic polymorphism
610   $aglycerophosphocholines
610   $ahuman brain
610   $ahydrogen peroxide
610   $alab-on-chip
610   $amicrofluidics
610   $amiRNAs
610   $amorphine
610   $an/a
610   $aNAD+
610   $aneurological diseases
610   $aneuroprotective
610   $aneurotransmitter
610   $anewborn infant
610   $anicotinamide
610   $aOpenArray
610   $aorgan-on-chip
610   $aOrthosiphon stamineus
610   $aplant-derived proteins
610   $aplasma
610   $aPPI
610   $aproteomics
610   $aregion
610   $aschizophrenia
610   $aSH-SY5Y cell model
610   $aSIDS
610   $aspatiotemporal network
610   $asphingolipids
610   $asynaptic plasticity
610   $awithdrawal
610   $azinc finger domain
610   $azinc finger motif
610   $azinc finger proteins
610   $azinc metalloproteins
615  7$aResearch & information: general
700   $aYoon$b Jong$4edt$01325352
702   $aVilla$b Chiara$4edt
702   $aYoon$b Jong$4oth
702   $aVilla$b Chiara$4oth
906   $aBOOK
912   $a9910557349303321
996   $aMulti-Omics for the Understanding of Brain Diseases$93036788
997   $aUNINA