LEADER 03664nam 2200961z- 450 001 9910557349303321 005 20231214132924.0 035 $a(CKB)5400000000042397 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/77075 035 $a(EXLCZ)995400000000042397 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMulti-Omics for the Understanding of Brain Diseases 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 electronic resource (204 p.) 311 $a3-0365-2602-1 311 $a3-0365-2603-X 330 $aOmics technologies such as proteomics, genomics, and metabolomics are widely applied for the identification and characterization of new molecular signatures. However, molecular profiling that makes it possible to understand neurodegenerative diseases has been relatively insufficient. Brain diseases such as neurodegenerative diseases and emotional disorders need integrative understanding which draws on a more reliable hypothesis for pathology, which can be accomplished via in-depth study of molecular information. Recently, multi-omics technologies have been eagerly applied to a diverse range of diseases. As this includes multiple molecular profiling, metadata, and Big Data processing with informatics and computer science, it is possible to provide new macroscopic and microscopic insights in order to better understand diseases. This Special Issue will introduce recent technological advances in multi-omics and the application of omics technology to brain diseases. 606 $aResearch & information: general$2bicssc 610 $aschizophrenia 610 $aabnormal behavior gene set 610 $aregion 610 $adifferentially expressed genes 610 $ade novo mutation 610 $acopy number variant 610 $aSIDS 610 $anewborn infant 610 $agenetic polymorphism 610 $aneurotransmitter 610 $aepigenetics 610 $aepigenome 610 $azinc finger domain 610 $azinc finger motif 610 $azinc finger proteins 610 $azinc metalloproteins 610 $aflow infusion analysis 610 $achloride adducts 610 $aceramides 610 $asphingolipids 610 $aglycerophosphocholines 610 $ahuman brain 610 $aNAD+ 610 $anicotinamide 610 $aageing 610 $aplasma 610 $abiomarker 610 $aCNV 610 $aPPI 610 $aspatiotemporal network 610 $achromosome 22q11.21 610 $aDGCR8 610 $aOrthosiphon stamineus 610 $aplant-derived proteins 610 $aneuroprotective 610 $aSH-SY5Y cell model 610 $ahydrogen peroxide 610 $aCSF 610 $amiRNAs 610 $aneurological diseases 610 $aOpenArray 610 $amorphine 610 $awithdrawal 610 $abrain 610 $aproteomics 610 $asynaptic plasticity 610 $aAlzheimer's disease 610 $amicrofluidics 610 $alab-on-chip 610 $a3D culture 610 $aorgan-on-chip 615 7$aResearch & information: general 700 $aYoon$b Jong$4edt$01325352 702 $aVilla$b Chiara$4edt 702 $aYoon$b Jong$4oth 702 $aVilla$b Chiara$4oth 906 $aBOOK 912 $a9910557349303321 996 $aMulti-Omics for the Understanding of Brain Diseases$93036788 997 $aUNINA