LEADER 06836nam 2202197z- 450 001 9910557336603321 005 20231214133443.0 035 $a(CKB)5400000000042512 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/77126 035 $a(EXLCZ)995400000000042512 100 $a20202201d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aThe Retina in Health and Disease 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 electronic resource (465 p.) 311 $a3-0365-2653-6 311 $a3-0365-2652-8 330 $aVision is the most important sense in higher mammals. The retina is the first step in visual processing and the window to the brain. It is not surprising that problems arising in the retina lead to moderate to severe visual impairments. We offer here a collection of reviews as well as original papers dealing with various aspects of retinal function as well as dysfunction. New approaches in retinal research are described, such as the expression and localization of the endocannabinoid system in the normal retina and the role of cannabinoid receptors that could offer new avenues of research in the development of potential treatments for retinal diseases. Moreover, new insights are offered in advancing knowledge towards the prevention and cure of visual pathologies, mainly AMD, RP, and diabetic retinopathy. 606 $aMedicine$2bicssc 606 $aNeurosciences$2bicssc 610 $aeye 610 $aretina 610 $adevelopment 610 $avascularization 610 $ahypoxia 610 $aautophagy 610 $aprogrammed cell death 610 $acellular senescence 610 $aretinogenesis 610 $aaltricial bird species 610 $aprecocial bird species 610 $asenescence-associated galactosidase activity 610 $adiabetes mellitus 610 $aretinopathy 610 $amicrovascular 610 $acomplication 610 $aoptical coherence tomography 610 $aangiography 610 $ablack 610 $aAfrican-American 610 $asystemic disease 610 $abiomarker 610 $aretinal degenerative diseases 610 $amesenchymal stem cells 610 $astem cell therapy 610 $aexperimental models 610 $aclinical trials 610 $aAMD 610 $aage-related macular degeneration 610 $atrichostatin A (TSA) 610 $aHDAC 610 $ahistone deacetylase 610 $avascular endothelial growth factor (VEGF) 610 $aretinal degeneration 610 $aendoplasmic reticulum 610 $astress response 610 $aunfolded protein response 610 $aGRP78 610 $aretinal glial cell 610 $adiabetic retinopathy 610 $azebrafish 610 $aneurovascular unit 610 $amicrovascular complications and dysfunction 610 $ametabolism 610 $amotor protein 610 $amyosin 1C 610 $aphotoreceptor 610 $arhodopsin 610 $aouter segments 610 $avisual function 610 $amacroglia 610 $aastrocytes 610 $aMu?ller cells 610 $aoptic nerve crush 610 $aretinal ganglion cells 610 $aspinal cord injury 610 $asignal transducer and activator of transcription 3 610 $aepidermal growth factor 610 $aDrp1 610 $aapoptosis 610 $amitochondria 610 $amicroglia 610 $aneurodegeneration 610 $amultiple sclerosis 610 $aretinal microglia 610 $amicroglia morphotype 610 $alight damage 610 $afunctional analysis 610 $aearly detection 610 $aremodeling 610 $alactate 610 $aGPR81 610 $aHCAR1 610 $agrowth cone 610 $adLGN 610 $aaxon 610 $a3,5-DHBA 610 $akallikrein-kinin system 610 $akinin receptors 610 $aGFAP 610 $aosteopontin 610 $aretinal detachment 610 $adiabetes 610 $aantioxidants 610 $abioenergetics 610 $arespiration 610 $aATP 610 $aglucagon-like peptide-1 610 $aexendin-4 610 $acatalase 610 $aimmunohistochemistry 610 $aelectron microscopy 610 $aCharles Bonnet syndrome 610 $aEEG 610 $avisual hallucination 610 $aresting state 610 $ahigh-fat diet 610 $agut microbiome 610 $agut-retina axis 610 $aRNA sequencing 610 $agerm-free mice 610 $acomplement cascade 610 $aangiogenesis 610 $aretinal inflammation 610 $aAII amacrine cell 610 $aProx1 610 $aparvalbumin 610 $agap junction 610 $aeccentricity 610 $aON/OFF asymmetry 610 $aarterioles 610 $abetulinic acid 610 $aischemia-reperfusion injury 610 $areactive oxygen species 610 $aretinal vessels 610 $aretinal fluorescence imaging 610 $aamyloid 610 $acognitive decline 610 $aAlzheimer's disease 610 $aoptic neuritis 610 $aoxidative stress 610 $aneuroprotection 610 $afingolimod 610 $aiPSC-RPE 610 $aretinal pigment epithelium 610 $aimmunodeficient RCS rat 610 $aultrathin parylene 610 $aretinal transplantation 610 $aCD4+CD25+ 610 $ainflammation 610 $aiPSC 610 $atypical cannabinoid receptors 610 $aatypical cannabinoid receptors 610 $aelectroretinography 610 $amonkeys 610 $avisual system 610 $aeye inflammation 610 $alipopolysaccharide 610 $anatural bioactive extracts 610 $aAc2-26 610 $aFPR receptor 610 $ainflammatory mediators 610 $aretinal light injury 610 $aLED screen 610 $aoptical filter 610 $aretinal protection 610 $aregeneration 610 $aprogenitor cell 610 $ahyperglycemia 610 $aphotoreceptors 610 $aneurod 610 $aNotch 615 7$aMedicine 615 7$aNeurosciences 700 $aPtito$b Maurice$4edt$01290173 702 $aBouskila$b Joseph$4edt 702 $aPtito$b Maurice$4oth 702 $aBouskila$b Joseph$4oth 906 $aBOOK 912 $a9910557336603321 996 $aThe Retina in Health and Disease$93021386 997 $aUNINA