LEADER 04473nam 2201021z- 450 001 9910557316703321 005 20231214133604.0 035 $a(CKB)5400000000042688 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69364 035 $a(EXLCZ)995400000000042688 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAdvances in Cross-Coupling Reactions 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 electronic resource (234 p.) 311 $a3-03943-567-1 311 $a3-03943-568-X 330 $aIn this Special Issue, recent advances in cross-coupling reactions are presented in the form of original research articles, reviews, and short communications. These contributions cover different topics in this area, including novel coupling reactions, reaction conditions, synthetic alternatives, metal ligands, and applications for new pharmaceutical compounds and organic materials. In particular, the reviews deal with methodologies such as the synthesis of diarylketones through palladium catalysis and the most relevant examples of Suzuki?Miyaura and Buchwald?Hartwig coupling reactions in the synthesis of bioactive compounds. The synthetic utility of cross-coupling reactions for the synthesis of medium-size rings and the utility of Stille and Suzuki coupling reactions for the synthesis of new molecular machines based on sterically hindered anthracenyl trypticenyl units are also summarized. The original research articles present the synthesis of 2-alkynylpyrrols by inverse Sonogashira coupling and the synthesis of indoles under oxidative dearomative cross-dehydrogenative conditions. The efficient combination of iridium-catalyzed C?H borylation of aryl halides with the Sonogashira coupling and a sequential iridium-catalyzed borylation of NH-free pyrroles followed by a Suzuki?Miyaura reaction are included. The synthesis of aryl propionic acids, a common structural motif in medicinal chemistry, and the synthesis of new organic dyes are also covered. 606 $aResearch & information: general$2bicssc 610 $across coupling 610 $adearomatization 610 $aC-H functionalization 610 $aindolin-3-ones 610 $adimerization and trimerization of indoles 610 $aC-H borylation 610 $aSonogashira cross-coupling 610 $aborylated aryl alkynes 610 $aone-pot reaction 610 $arestricted rotations 610 $aM(CO)3 tripods 610 $amolecular brakes and gears 610 $aX-ray 610 $aV-T NMR 610 $aborylation 610 $aSuzuki coupling 610 $aNH-Free 610 $a5-aryl pyrrole-2-carboxylates 610 $airidium-catalyzed 610 $aheteroaryl substituted pyrroles 610 $a2,3'-bipyrrole 610 $aelectrophilic haloacetylenes 610 $apyrroles 610 $aethynylpyrroles 610 $afurans 610 $athiophenes 610 $apyrazoles 610 $aAl2O3 610 $atransition-metal catalysis 610 $aintramolecular cyclization 610 $amedium-sized heterocycles 610 $aC-H activation 610 $aacylation 610 $apalladium 610 $aarenes 610 $aheteroarenes 610 $aindigo dyes 610 $aDSSC 610 $asynthesis 610 $aspectroscopy 610 $aHeck reaction 610 $astyrene 610 $amethoxycarbonylation 610 $aprofene 610 $across-coupling reactions 610 $aC-C bond forming reactions 610 $aC-Heteroatom bond forming reactions 610 $aclinical candidate 610 $aDNA-encoded libraries 610 $acyclopeptides 610 $aallosteric modulators 610 $aPROTAC 610 $acatalysis in water 610 $aC-C cross-coupling 610 $aSuzuki-Miyaura reaction 610 $asulfonated salan 615 7$aResearch & information: general 700 $aPe?rez Sestelo$b Jose?$4edt$01326443 702 $aSarandeses$b Luis A$4edt 702 $aPe?rez Sestelo$b Jose?$4oth 702 $aSarandeses$b Luis A$4oth 906 $aBOOK 912 $a9910557316703321 996 $aAdvances in Cross-Coupling Reactions$93037438 997 $aUNINA