LEADER 04330nam 2201105z- 450 001 9910557307703321 005 20231214133454.0 035 $a(CKB)5400000000042779 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69113 035 $a(EXLCZ)995400000000042779 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aThe Alveolar Epithelium$eMechanisms of Injury and Repair 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 electronic resource (222 p.) 311 $a3-03943-166-8 311 $a3-03943-167-6 330 $aAlveolar epithelial cells (AECs) of the lung are important contributors to pulmonary immune functions and to pulmonary development and alveolar repair mechanisms following lung injury. AECI, together with the capillary endothelium, form the extremely thin barrier between alveolar air and blood. AECII produce and metabolize the surface-tension lowering and immune-modulating surfactant and are the progentiors of AECI. A great variety of processes rely on their normal functioning, including maintenance of the alveolar barrier; innate immune defense; and processes of differentiation, senescence, apoptosis, and autophagy. The wide range of AEC functions is nicely reflected by the diversity of topics addressed by the four review and eight original articles contained in this Special Issue of the International Journal of Molecular Sciences. Beyond the broad spectrum of topics, the authors of this issue also made use of an impressive variety of analytical methods, thus further illustrating the fascinating diversity of aspects related to AEC biology. 517 $aAlveolar Epithelium 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 610 $aJAM-A 610 $aP2X7 receptor 610 $amouse lung 610 $aalveolar epithelium 610 $ableomycin-induced lung injury 610 $aGSK-3? 610 $adietary sugar 610 $ahyperglycemia 610 $alung mechanics 610 $aalveolar septal composition 610 $aphysical activity 610 $aextracellular matrix remodeling 610 $ahigh-altitude pulmonary edema 610 $aacute mountain sickness 610 $aoxygen diffusion limitation 610 $asurfactant protein B 610 $aatelectrauma 610 $aalveolar fluid 610 $aacinar micromechanics 610 $aacute lung injury 610 $aautophagy 610 $alysosome 610 $alysosomal membrane permeability 610 $amitochondria 610 $apneumocyte 610 $amicroRNA-21 610 $aalveolar micromechanics 610 $astructural remodeling 610 $ainflammatory signaling 610 $alung 610 $aalveolus 610 $atype 1 alveolar epithelial cell 610 $atype 2 alveolar epithelial cell 610 $afocused ion beam scanning electron microscopy 610 $a3D reconstruction 610 $acarbon dioxide 610 $ahypercapnia 610 $aNa,K-ATPase 610 $aendoplasmic reticulum 610 $asodium transport 610 $aprotein oxidation 610 $aalveolar epithelial cells 610 $apulmonary fibrosis 610 $aepithelial cell dysfunction 610 $astem cell exhaustion 610 $apneumonia 610 $anecrotizing 610 $aregeneration 610 $amodel 610 $abovine 610 $achlamydia 610 $aalveoli 610 $aair-blood barrier 610 $aepithelium 610 $aair-liquid interface 610 $aalveolar lining layer 610 $aglycocalyx 610 $asurfactant 610 $alung injury 610 $alung regeneration 615 7$aResearch & information: general 615 7$aBiology, life sciences 700 $aKasper$b Michael$4edt$01328754 702 $aMühlfeld$b Christian$4edt 702 $aKasper$b Michael$4oth 702 $aMühlfeld$b Christian$4oth 906 $aBOOK 912 $a9910557307703321 996 $aThe Alveolar Epithelium$93038905 997 $aUNINA