LEADER 04339nam 2201237z- 450 001 9910557297503321 005 20210501 035 $a(CKB)5400000000041064 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/68511 035 $a(oapen)doab68511 035 $a(EXLCZ)995400000000041064 100 $a20202105d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aZika Virus and Host Interactions 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 online resource (256 p.) 311 08$a3-03943-949-9 311 08$a3-03943-950-2 330 $aZika virus (ZIKV), one of the flavivirus family members transmitted by mosquitos, was declared a Public Health Emergency of International Concern by the WHO in February 2016 because of clusters of newborn microcephaly cases and other neurological disorders in Brazil. Most ZIKV infections result in a self-limited flu-like febrile disease, however, if contracted during pregnancy, the virus can also infect fetuses and cause a spectrum of birth defects known as congenital Zika syndrome. To date, no vaccines or antiviral drugs are licensed for ZIKV, and the virus has spread and become endemic to many tropical and sub-tropical countries. Included in this book are thirteen reports addressing diverse aspects of ZIKV-host interactions. These studies range from basic science to clinical research. It is expected that findings from these studies will contribute to a better understanding of the host cells interacting with ZIKV, and may serve as the basis for new diagnostics, antiviral therapies, and vaccine design. 606 $aBiology, life sciences$2bicssc 606 $aResearch and information: general$2bicssc 610 $aanti-viral signaling 610 $aapoptosis 610 $aarboviruses 610 $aastrocytes 610 $aBcl-2 protein family 610 $ablood-placental barrier 610 $aC6/36 cells 610 $acell death 610 $acell entry 610 $acellular communication 610 $aclaudins 610 $acytokine 610 $aendothelial vascular cells 610 $aenvelope protein 610 $aextracellular vesicles 610 $afetal brain 610 $aflavivirus 610 $aflaviviruses 610 $afusion loop 610 $aglycosylation 610 $aguinea pig 610 $ahost 610 $ahost-pathogen interactions 610 $aHSP90 610 $ahuman monocytes 610 $aIFN 610 $aIFNAR1 610 $aimmune response 610 $ainfertility 610 $ainflammation 610 $ainflammatory mediator 610 $ainnate immune response 610 $ainnate immunity 610 $ainterferon 610 $aJAK/STAT 610 $aLeydig cells 610 $aMDA5 610 $amosquito 610 $aMR766 610 $anetwork 610 $anon-structural viral proteins 610 $aNS5 610 $aNS5 protein 610 $anuclear localization 610 $apathogenesis 610 $aperoxisome 610 $aperoxisomes 610 $aplacenta 610 $aprotein-protein interaction 610 $aRIG-I 610 $aSertoli cells 610 $asexual transmission 610 $asubcutaneous 610 $aT cells 610 $atight junction 610 $atight junctions 610 $avaginal 610 $aviral fusion 610 $aviral replication 610 $avirus host interactions 610 $avirus transmission 610 $avirus-host interactions 610 $aWest Nile virus 610 $azika 610 $azika virus 610 $aZika virus 610 $aZIKA virus 610 $aZIKV 610 $aZO-1 615 7$aBiology, life sciences 615 7$aResearch and information: general 700 $aHobman$b Tom$4edt$01283267 702 $aKumar$b Anil$4edt 702 $aLimonta$b Daniel$4edt 702 $aHobman$b Tom$4oth 702 $aKumar$b Anil$4oth 702 $aLimonta$b Daniel$4oth 906 $aBOOK 912 $a9910557297503321 996 $aZika Virus and Host Interactions$93019085 997 $aUNINA LEADER 01688nas 2200445 a 450 001 9910891407903321 005 20211020051820.0 011 $a1990-0422 035 $a(OCoLC)32689669 035 $a(CKB)2590000000002905 035 $a(CONSER)sn 95029104 035 $a(DE-599)ZDB2703069-6 035 $a(NjHacI)992590000000002905 035 $a(EXLCZ)992590000000002905 100 $a19950622a199u9999 uy 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 04$aThe measurement of scientific and technological activities 210 1$aParis :$cOrganisation for Economic Co-operation and Development,$d1993- 215 $a1 online resource 225 1 $aThe Measurement of Scientific and Technological Activities 300 $a"Proposed standard practice for surveys of research and experimental development." 311 08$a1990-0414 330 3 $aThis series provides publications containing methodological guidelines for the collection of data on R&D expenditures, patents, R&D human resources and innovation. 410 0$aThe Measurement of Scientific and Technological Activities 606 $aResearch$xStatistical methods$vHandbooks, manuals, etc 606 $aScientific surveys$vHandbooks, manuals, etc 615 0$aResearch$xStatistical methods 615 0$aScientific surveys 676 $a001.422 712 02$aOrganisation for Economic Co-operation and Development. 801 0$bNjHacI 801 1$bNjHacl 906 $aJOURNAL 912 $a9910891407903321 996 $aThe measurement of scientific and technological activities$94271391 997 $aUNINA