LEADER 04007nam 2201033z- 450 001 9910557291103321 005 20210501 035 $a(CKB)5400000000041128 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69153 035 $a(oapen)doab69153 035 $a(EXLCZ)995400000000041128 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (128 p.) 311 08$a3-03936-658-0 311 08$a3-03936-659-9 330 $aTuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Health Organization (WHO), TB is considered the ninth cause of death worldwide and the leading cause of mortality by a single infectious agent, with the highest rate of infections and death toll rate mostly concentrated in developing and low-income countries. We present here the editorial section to the Special Issue entitled "Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment" that includes 7 research articles and a review. The scientific contributions included in the Special Issue mainly focus on the characterization of MTB strains emerging in TB endemic countries as well as on multiple mechanisms adopted by the bacteria to resist and to adapt to antitubercular therapies. 606 $aBiology, life sciences$2bicssc 606 $aResearch & information: general$2bicssc 610 $aantitubercular drug discovery 610 $aantitubercular treatments 610 $aapoptosis 610 $aBeijing B0/W148 610 $aBeijing genotype 610 $aBM-MSCs 610 $abone-homing 610 $aCD38 610 $aCentral Asia Outbreak 610 $acytokine 610 $adrug discovery 610 $adrug resistance 610 $adrug target 610 $aeffector 610 $aefflux 610 $agene expression 610 $aHLA-DR 610 $ahost-pathogen interactions 610 $aIL-18 610 $aIL-18BP 610 $aIL-18R 610 $aimidazo[1,2-b][1,2,4,5]tetrazine 610 $aimmune activation 610 $aimmune response 610 $alatent tuberculosis 610 $aline probe assay 610 $aliposomes 610 $aM. tuberculosis 610 $amacrophage 610 $aMDR-TB 610 $amicroRNA 610 $aMmpS5-MmpL5 610 $aMtb 610 $amurine infection model 610 $aMycobacterium 610 $aMycobacterium avium 610 $aMycobacterium smegmatis 610 $aMycobacterium tuberculosis 610 $aomics analysis 610 $apre-XDR-TB 610 $arelapse 610 $asecond-line drugs 610 $astem cell niche 610 $asubtractive genomics 610 $asystem analysis 610 $aTB treatment 610 $atreatment response 610 $atuberculosis 610 $auncharacterized proteins 610 $aunique metabolic pathways 610 $aVirulence 610 $aXDR-TB 615 7$aBiology, life sciences 615 7$aResearch & information: general 700 $aFerraris$b Davide Maria$4edt$01296151 702 $aMiggiano$b Riccardo$4edt 702 $aRizzi$b Menico$4edt 702 $aFerraris$b Davide Maria$4oth 702 $aMiggiano$b Riccardo$4oth 702 $aRizzi$b Menico$4oth 906 $aBOOK 912 $a9910557291103321 996 $aMycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment$93023812 997 $aUNINA