LEADER 03935nam 2200937z- 450 001 9910557289503321 005 20231214133239.0 035 $a(CKB)5400000000041145 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69438 035 $a(EXLCZ)995400000000041145 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBiomaterial-Related Infections 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 electronic resource (204 p.) 311 $a3-03943-438-1 311 $a3-03943-439-X 330 $aThe use of medical devices (e.g., catheters, implants, and probes) is a common and essential part of medical care for both diagnostic and therapeutic purposes. However, these devices quite frequently lead to the incidence of infections due to the colonization of their abiotic surfaces by biofilm-growing microorganisms, which are progressively resistant to antimicrobial therapies. Several methods based on anti-infective biomaterials that repel microbes have been developed to combat device-related infections. Among these strategies, surface coating with antibiotics (e.g., beta-lactams), natural compounds (e.g., polyphenols), or inorganic elements (e.g., silver and copper nanoparticles) has been widely recognized as exhibiting broad-spectrum bactericidal or bacteriostatic activity. So, in order to achieve a better therapeutic response, it is crucial to understand how these infections are different from others. This will allow us to find new biomaterials characterized by antifouling coatings with repellent properties or low adhesion towards microorganisms, or antimicrobial coatings that are capable of killing microbes approaching the surface, improving biomaterial functionalization strategies and supporting tissues? bio-integration. 606 $aMedicine$2bicssc 610 $aCandida 610 $abiofilms 610 $adiabetes 610 $amedical devices 610 $acandidiasis 610 $ametabolic disorder 610 $ahyperglycemia 610 $ainfection 610 $aCandida glabrata 610 $acandidemia 610 $aechinocandins 610 $aresistance 610 $amicafungin 610 $acaspofungin 610 $ain vivo 610 $atitanium dioxide 610 $ananotubes 610 $aautoclaving 610 $atitanium alloy 610 $abiocompatibility 610 $awettability 610 $amechanical properties 610 $asilver nanoparticles 610 $atitanium dioxide nanotubes 610 $asilver ions release 610 $abiointegration 610 $aantimicrobial activity 610 $apolyethylene terephthalate 610 $aPET 610 $aelectrospinning 610 $ananofibers 610 $aantimicrobial agents 610 $aTaguchi method 610 $aantimicrobial efficiency 610 $acold atmospheric-pressure plasma jet (CAPJ) 610 $aEscherichia coli 610 $aDNA double-strand breaks 610 $ascanning electron microscopy 610 $aTi6Al4V implants 610 $aanodization process 610 $aXPS 610 $agenotoxicity assessment 610 $aanti-inflammatory properties 610 $aoral biofilm 610 $ainfection control 610 $aStreptococcus mutans 610 $aCandida spp. 610 $anatural compounds 610 $aantimicrobial resistance 615 7$aMedicine 700 $aRodrigues$b Ce?lia F$4edt$01324789 702 $aMartins$b Nata?lia$4edt 702 $aRodrigues$b Ce?lia F$4oth 702 $aMartins$b Nata?lia$4oth 906 $aBOOK 912 $a9910557289503321 996 $aBiomaterial-Related Infections$93036301 997 $aUNINA