LEADER 03958nam 2200793z- 450 001 9910557287803321 005 20231214133146.0 035 $a(CKB)5400000000041162 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/68938 035 $a(EXLCZ)995400000000041162 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAntimicrobial Resistance in Horses 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 electronic resource (124 p.) 311 $a3-03936-712-9 311 $a3-03936-713-7 330 $aAntimicrobial resistance (AMR) is a global problem with extremely complex epidemiology involving the direct and indirect transmission of antibiotic resistant pathogens and mobile genetic elements between humans, animals, and the environment. AMR is, therefore, recognized as a ?One Health? issue. Data that describe AMR prevalence and trends are required to enable the judicious and prudent use of antimicrobials in animals, which has implications both from veterinary and animal welfare aspects as well as from a zoonotic and public health perspective. Horses are a potential reservoir of AMR for humans due to close human?animal contact, as was demonstrated with shared human and horse methicillin-resistant Staphylococcus aureus (MRSA) strains causing outbreaks in equine hospitals. Extended-spectrum beta-lactamase-producing Enterobacteriaceae, considered as clinically and economically important to the AMR burden in human and veterinary medicine, has been reported in both community and clinic equine populations. Strains of Enterobacteriaceae pose a major worldwide threat due to the geographical expansion of ESBL-producing clones as well as the horizontal interspecies dissemination of ESBL-encoding plasmids and genes. In human medicine, ESBL-E infection is associated with increased morbidity, mortality, length of hospital stay, delay of targeted appropriate treatment, and higher costs. These issues also need to be addressed in horses. This Special Issue on AMR in horses encompasses several papers that describe the prevalence, risk factors, and molecular data on MDR bacteria in healthy horses in Canada, Japan, Spain, and Israel, in addition to papers that describe the clinical impact of MDR bacteria in diseased horses in Austria, USA, France and Israel. 606 $aHumanities$2bicssc 606 $aSocial interaction$2bicssc 610 $aequine 610 $afoal 610 $aESBL-E 610 $aantibiotic resistance 610 $ashedding 610 $aumbilical infection 610 $arisk factors 610 $ahealthy horses 610 $astaphylococci 610 $aMSSA 610 $aST1640 610 $alukPQ 610 $aESBL 610 $aEscherichia coli 610 $aEnterobacteriaceae 610 $aantimicrobial resistance 610 $aCTX-M-1 610 $aSHV 610 $afarm 610 $aESBL-E acquisition 610 $aAmpC 610 $aKlebsiella pneumoniae 610 $aantibiotic-resistance 610 $a?-lactamases 610 $ahorses 610 $aextended-spectrum ?-lactamase 610 $aAmpC ?-lactamase 610 $ahorse 610 $amultidrug resistance 610 $abeta-lactamase 610 $acephalosporinase 610 $amicrobiota 610 $aNorth America 610 $ahorse pathogens 610 $aepidemiology 615 7$aHumanities 615 7$aSocial interaction 700 $aSteinman$b Amir$4edt$01293810 702 $aNavon-Venezia$b Shiri$4edt 702 $aSteinman$b Amir$4oth 702 $aNavon-Venezia$b Shiri$4oth 906 $aBOOK 912 $a9910557287803321 996 $aAntimicrobial Resistance in Horses$93022735 997 $aUNINA