LEADER 02067nam  2200421z- 450 
001 9910557255203321
005 20231214133045.0
035   $a(CKB)5400000000041405
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/73756
035   $a(EXLCZ)995400000000041405
100   $a20202111d2020      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aT Cell Differentiation and Function in Tissue Inflammation
210   $cFrontiers Media SA$d2020
215   $a1 electronic resource (231 p.)
311   $a2-88963-614-3 
330   $aHelper T cells play a critical role in the induction of tissue inflammation in immunity and autoimmunity. Various subsets of T cells such as Th1, Th2, Th9 and Th17 cells have been shown to play a key role in the induction of tissue inflammation in allergic and organ-specific autoimmune inflammation. On the other hand, regulatory cells such as Foxp3+Tregs and Tr1 cells are essential to control functions of effector T cells and maintain tissue homeostasis. Distinct transcriptional and molecular pathways have been identified for the generation of various effector and regulatory T cells. Emerging molecular signatures of these effectors and of regulatory T cells indicate plasticity in their developmental pathways, which is dictated by the tissue microenvironment and by other factors including cytokines and transcription factors.
606   $aMedicine$2bicssc
606   $aImmunology$2bicssc
610   $aCD4 T cell
610   $aCD8 T cell
610   $aCancer
610   $aautoimmune disease
610   $aInflammation
615  7$aMedicine
615  7$aImmunology
700   $aAwasthi$b Amit$4edt$01302748
702   $aGoswami$b Ritobrata$4edt
702   $aAwasthi$b Amit$4oth
702   $aGoswami$b Ritobrata$4oth
906   $aBOOK
912   $a9910557255203321
996   $aT Cell Differentiation and Function in Tissue Inflammation$93026510
997   $aUNINA