LEADER 04304nam 2200565z- 450 001 9910557254303321 005 20211118 035 $a(CKB)5400000000041414 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/73781 035 $a(oapen)doab73781 035 $a(EXLCZ)995400000000041414 100 $a20202111d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aThe Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition 210 $cFrontiers Media SA$d2020 215 $a1 online resource (312 p.) 311 08$a2-88963-639-9 330 $aThere is a large market demand for new drugs. The existing chronic or common ailments without cures, development of new diseases with unknown causes, and the widespread existence of antibiotic-resistant pathogens, have driven this field of research further by looking at all potential sources of natural products. To date, microbes have made a significant contribution to the health and well-being of people globally. The discoveries of useful metabolites produced by microbes have resulted in a significant proportion of pharmaceutical products in today's market. Therefore, the investigation and identification of bioactive compound(s) producing microbes is always of great interest to researchers. Actinobacteria are one of the most important and efficient groups of natural metabolite producers. Among the numerous genera, Streptomyces have been recognized as prolific producers of useful natural compounds, as they provide more than half of the naturally-occurring antibiotics isolated to-date and continue to emerge as the primary source of new bioactive compounds. Certainly, these potentials have attracted ample research interest and a wide range of biological activities have been subsequently screened by researchers with the utilization of different In vitro and In vivo model of experiments. Literature evidence has shown that a significant number of interesting compounds produced by Actinobacteria were exhibiting either strong anticancer or neuroprotective activity. The further in depth studies have then established the modulation of apoptotic pathway was involved in those observed bioactivities. These findings indirectly prove the biopharmaceutical potential possessed by Actinobacteria and at the same time substantiate the importance of diverse pharmaceutical evaluations on Actinobacteria. In fact, many novel compounds discovered from Actinobacteria with strong potential in clinical applications have been developed into new drugs by pharmaceutical companies. Together with the advancement in science and technology, it is predicted that there would be an expedition in discoveries of new bioactive compounds producing Actinobacteria from various sources, including soil and marine sources. In light of these current needs, and great interest in the scope of this research, this book seeks to contribute on the investigation of different biological active compound(s) producing actinobacteria which are exhibiting antimicrobial, antioxidant, neuroprotective, anticancer activities and similar. 517 $aSearch for Biological Active Agent 606 $aMedical microbiology & virology$2bicssc 606 $aMicrobiology (non-medical)$2bicssc 606 $aScience: general issues$2bicssc 610 $aactinobacteria 610 $abioactive 610 $adrug discovery 610 $amarine 610 $anext generation 610 $aStreptomyces 610 $aterrestrial 615 7$aMedical microbiology & virology 615 7$aMicrobiology (non-medical) 615 7$aScience: general issues 700 $aLee$b Learn-Han$4edt$01326374 702 $aChan$b Kok-Gan$4edt 702 $aStach$b Jem$4edt 702 $aWellington$b Elizabeth M. H$4edt 702 $aGoh$b Bey-Hing$4edt 702 $aLee$b Learn-Han$4oth 702 $aChan$b Kok-Gan$4oth 702 $aStach$b Jem$4oth 702 $aWellington$b Elizabeth M. H$4oth 702 $aGoh$b Bey-Hing$4oth 906 $aBOOK 912 $a9910557254303321 996 $aThe Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition$93038216 997 $aUNINA LEADER 04159nam 22005415 450 001 9910253921603321 005 20200706203626.0 010 $a3-319-58292-5 024 7 $a10.1007/978-3-319-58292-4 035 $a(CKB)4340000000061988 035 $a(MiAaPQ)EBC4908638 035 $a(DE-He213)978-3-319-58292-4 035 $a(PPN)203671538 035 $a(EXLCZ)994340000000061988 100 $a20170710d2017 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aMutualisms and Insect Conservation /$fby Tim R. New 205 $a1st ed. 2017. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2017. 215 $a1 online resource (232 pages) $cillustrations 311 $a3-319-58291-7 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $a1 The Scope and Meaning of Mutualisms -- 2 Mechanisms and Maintenance -- 3 Classic Themes: Pollination Mutualisms of Insects and Plants -- 4 Classic Themes: Ants, Plants and Fungi -- 5 Classic Themes: Ants and Other Insects. Hemiptera -- 6 Classic Themes: Ants and Other Insects. Lepidoptera -- 7 Classic Themes: Other Insect Mutualisms -- 8 Impacts of Alien Invasive Species -- 9 Exploiters of Mutualisms -- 10 Habitat Losses and Conservation of Mutualisms. 330 $aDocumenting and understanding intricate ecological interactions involving insects is a central need in conservation, and the specialised and specific nature of many such associations is displayed in this book. Their importance is exemplified in a broad global overview of a major category of interactions, mutualisms, in which the interdependence of species is essential for their mutual wellbeing. The subtleties that sustain many mutualistic relationships are still poorly understood by ecologists and conservation managers alike. Examples from many parts of the world and ecological regimes demonstrate the variety of mutualisms between insect taxa, and between insects and plants, in particular, and their significance in planning and undertaking insect conservation ? of both individual species and the wider contexts on which they depend. Several taxonomic groups, notably ants, lycaenid butterflies and sucking bugs, help to demonstrate the evolution and flexibility of mutualistic interactions, whilst fundamental processes such as pollination emphasise the central roles of, often, highly specific partnerships. This compilation brings together a wide range of relevant cases and contexts, with implications for practical insect conservation and increasing awareness of the roles of co-adaptations of behaviour and ecology as adjuncts to designing optimal conservation plans. The three major themes deal with the meanings and mechanisms of mutualisms, the classic mutualisms that involve insect partners, and the environmental and conservation lessons that flow from these and have potential to facilitate and improve insect conservation practice. The broader ecological perspective advances the transition from primary focus on single species toward consequently enhancing wider ecological contexts in which insect diversity can thrive. 606 $aEntomology 606 $aApplied ecology 606 $aConservation biology 606 $aEcology 606 $aEntomology$3https://scigraph.springernature.com/ontologies/product-market-codes/L25090 606 $aApplied Ecology$3https://scigraph.springernature.com/ontologies/product-market-codes/L19023 606 $aConservation Biology/Ecology$3https://scigraph.springernature.com/ontologies/product-market-codes/L19150 615 0$aEntomology. 615 0$aApplied ecology. 615 0$aConservation biology. 615 0$aEcology. 615 14$aEntomology. 615 24$aApplied Ecology. 615 24$aConservation Biology/Ecology. 676 $a333.955 700 $aNew$b Tim R$4aut$4http://id.loc.gov/vocabulary/relators/aut$0872813 906 $aBOOK 912 $a9910253921603321 996 $aMutualisms and Insect Conservation$92234121 997 $aUNINA