LEADER 04374nam 2200673Ia 450 001 9910782081303321 005 20230912133155.0 010 $a1-282-86047-X 010 $a9786612860478 010 $a0-7735-7022-5 024 7 $a10.1515/9780773570221 035 $a(CKB)1000000000521346 035 $a(SSID)ssj0000284487 035 $a(PQKBManifestationID)11228401 035 $a(PQKBTitleCode)TC0000284487 035 $a(PQKBWorkID)10268811 035 $a(PQKB)10089094 035 $a(CaPaEBR)400477 035 $a(Au-PeEL)EBL3331200 035 $a(CaPaEBR)ebr10141873 035 $a(CaONFJC)MIL286047 035 $a(OCoLC)929121543 035 $a(DE-B1597)656777 035 $a(DE-B1597)9780773570221 035 $a(VaAlCD)20.500.12592/2s0h6r 035 $a(schport)gibson_crkn/2009-12-01/1/400477 035 $a(MiAaPQ)EBC3331200 035 $a(MiAaPQ)EBC3245545 035 $a(EXLCZ)991000000000521346 100 $a20020814d2002 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSteps on the road to medicare$b[electronic resource] $ewhy Saskatchewan led the way /$fC. Stuart Houston 210 $aMontreal ;$aIthaca $cMcGill-Queen's University Press$dc2002 215 $ax, 163 p. $cill., ports. ;$d23 cm 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-7735-2550-5 311 $a0-7735-2366-9 320 $aIncludes bibliographical references (p. [129-154]) and index. 327 $tFront Matter -- $tContents -- $tAbbreviations -- $tAcknowledgments -- $tForeword -- $tIntroduction -- $tSaskatchewan Hospitals: Off to a Slow Star -- $tDr Seymour -- $tMunicipal Doctors and Municipal Hospitals -- $tDr Ferguson and Tuberculosis -- $tSigerist and Pensioners? Care -- $tSwift Current Health Region -- $tMedical College and University Hospital -- $tProvince-wide Hospitalization -- $tInnovations in Psychiatry -- $tHigh-voltage Cancer Treatment -- $tEpilogue -- $tNotes -- $tIndex 330 $aIn Steps on the Road to Medicare Stuart Houston shows that Saskatchewan has led in the development of publicly funded health care since 1915. Among Saskatchewan's many firsts were the payment of municipal doctors, the development of municipal hospitals, and advances in the treatment and prevention of tuberculosis - then the leading cause of death - that culminated in January 1929 with universal free diagnosis and treatment of TB. Given this background of leadership, it was logical for North America's first social democratic government, the CCF, led by Tommy Douglas, to go further, beginning with medical care for pensioners and widows. This was quickly followed by a universal, comprehensive health care plan, instituted in the Swift Current region in July 1945, two years before Britain began such a program. Universal, province-wide hospitalization insurance was put in place in January 1946. Advances in psychiatry consisted of the first inclusion of psychotic patients in an open psychiatric ward in a general teaching hospital in 1955, while cancer firsts included the first government-sponsored cancer clinics, the first full-time cancer physicist, and the world's first use of calibrated betatron and cobalt-60 machines for treating cancer. Why was Saskatchewan so consistently first in health care? Houston argues that not only was the population both altruistic and ingenious with a well-developed spirit of co-operation but that its leaders, including Maurice Seymour, R.G. Ferguson, Harold Johns, and Tommy Douglas, showed unusual foresight. He details how from 1915 through 1962 government responded quickly to public need and suggests that it should be equally responsive today. 606 $aMedical care$zSaskatchewan$xHistory$y20th century 606 $aMedical policy$zSaskatchewan$xHistory$y20th century 606 $aHealth care reform$zSaskatchewan$xHistory$y20th century 615 0$aMedical care$xHistory 615 0$aMedical policy$xHistory 615 0$aHealth care reform$xHistory 676 $a362.1/097124/0904 700 $aHouston$b C. Stuart$g(Clarence Stuart),$f1927-$01464668 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910782081303321 996 $aSteps on the road to medicare$93800903 997 $aUNINA LEADER 04464nam 2201117z- 450 001 9910557141203321 005 20210501 035 $a(CKB)5400000000040647 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/68554 035 $a(oapen)doab68554 035 $a(EXLCZ)995400000000040647 100 $a20202105d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aSample Preparation in Metabolomics 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 online resource (208 p.) 311 08$a3-03943-813-1 311 08$a3-03943-814-X 330 $aMetabolomics is increasingly being used to explore the dynamic responses of living systems in biochemical research. The complexity of the metabolome is outstanding, requiring the use of complementary analytical platforms and methods for its quantitative or qualitative profiling. In alignment with the selected analytical approach and the study aim, sample collection and preparation are critical steps that must be carefully selected and optimized to generate high-quality metabolomic data. This book showcases some of the most recent developments in the field of sample preparation for metabolomics studies. Novel technologies presented include electromembrane extraction of polar metabolites from plasma samples and guidelines for the preparation of biospecimens for the analysis with high-resolution ? magic-angle spinning nuclear magnetic resonance (HR-?MAS NMR). In the following chapters, the spotlight is on sample preparation approaches that have been optimized for diverse bioanalytical applications, including the analysis of cell lines, bacteria, single spheroids, extracellular vesicles, human milk, plant natural products and forest trees. 606 $aMedicine and Nursing$2bicssc 610 $a20% FCS 610 $aAMOPLS 610 $aAsPC-1 610 $abiomarkers 610 $acapillary electrophoresis-mass spectrometry 610 $acapillary electrophoresis-mass spectrometry (CE-MS) 610 $acardiovascular disease 610 $acell line 610 $adatabases 610 $adesign of experiments 610 $adiagnostics 610 $adrug discovery 610 $aelectromembrane extraction 610 $aexosomes 610 $aextracellular vesicles 610 $aextraction 610 $aforestry 610 $agas chromatography 610 $agas chromatography-mass spectrometry (GC-MS) 610 $aGC-MS 610 $aharvesting 610 $ahigh resolution mass spectrometry 610 $ahigh-resolution magic angle spinning 610 $ahuman cell line 610 $ahuman milk 610 $ahuman plasma 610 $ahydrophilic interaction liquid chromatography 610 $aion mobility spectrometry 610 $aIT-139 610 $aKP1339 610 $aLC-MS 610 $aLC-MS/MS 610 $alipidomics 610 $aliquid chromatography 610 $aliquid chromatography-mass spectrometry 610 $aliquid chromatography-mass spectrometry (LC-MS) 610 $amass spectrometry 610 $ametabolic pathways 610 $ametabolic profiling 610 $ametabolite extraction 610 $ametabolites 610 $ametabolome 610 $ametabolomics 610 $ametabonomics 610 $ametadata standardization 610 $ametallodrugs 610 $amethod development 610 $aMiaPaCa-2 610 $amicroscopic samples 610 $amicrovesicles 610 $amulti-segment injection 610 $amulticellular tumor spheroids 610 $aNMR 610 $anormalization 610 $anuclear magnetic resonance (NMR) 610 $anuclear magnetic resonance spectroscopy 610 $aoxaliplatin 610 $aPanc-1 610 $aplant metabolomics 610 $aplant natural products 610 $asample preparation 610 $asampling 610 $atrees 615 7$aMedicine and Nursing 700 $aKuligowski$b Julia$4edt$01302968 702 $aQuintás$b Guillermo$4edt 702 $aKuligowski$b Julia$4oth 702 $aQuintás$b Guillermo$4oth 906 $aBOOK 912 $a9910557141203321 996 $aSample Preparation in Metabolomics$93026786 997 $aUNINA