LEADER 03780nam 2201093z- 450 001 9910557134903321 005 20231214132836.0 035 $a(CKB)5400000000040704 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/68453 035 $a(EXLCZ)995400000000040704 100 $a20202105d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aOxidative Stress in Diabetic Retinopathy 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 electronic resource (322 p.) 311 $a3-0365-0448-6 311 $a3-0365-0449-4 330 $aThe combination of an increasing prevalence of diabetes and the aging of populations enables the appearance of a greater number of associated complications such as diabetic retinopathy. Diabetic retinopathy is the leading cause of preventable vision loss in working-age adults. The objective of this Special Issue is to highlight the existing evidence regarding the relationship between oxidative stress and low-grade chronic inflammation induced by hyperglycemia with the development and progression of diabetic retinopathy, with an emphasis on the importance of early diagnosis and the use of antioxidant and anti-inflammatory approaches to prevent or delay the harmful effects of diabetes on retinal tissue. 606 $aMedicine$2bicssc 610 $aeicosanoids 610 $aoxidative stress 610 $adiabetic retinopathy 610 $acyclooxygenase 610 $alipoxygenase 610 $aCytochrome P450 610 $aHDAC6 610 $atubastatin A 610 $aretinal endothelial cells 610 $aretinal endothelial cell senescence 610 $adb/db mice 610 $aCinnamomi Ramulus 610 $aPaeoniae Radix 610 $aCPA4-1 610 $ablood-retinal barrier 610 $aoccludin 610 $ahuman retina 610 $aepiretinal membrane 610 $ainternal limiting membrane 610 $avitreoretinal surgery 610 $amacular hole 610 $aproliferative diabetic retinopathy 610 $aantioxidants 610 $adiabetes mellitus 610 $afree radicals 610 $ahigh-mobility group box 1 (HMGB1) 610 $ainflammatory pathways 610 $anovel therapies 610 $adiabetic retinopathy (DR) 610 $ainflammation 610 $aangiogenesis 610 $aextracellular vesicles 610 $amiRNA 610 $abiomarkers 610 $aapoptosis 610 $afenofibrate 610 $athioredoxin 610 $ahyperglycemia 610 $aastaxanthin 610 $acarotenoid 610 $areactive oxygen species 610 $aphotoreceptor cells 610 $aPI3K 610 $aNrf2 610 $aeicosapentaenoic acid (EPA) 610 $adocosahexaenoic acid (DHA) 610 $aretinal pigment epithelium 610 $aantioxidant 610 $aascorbic acid 610 $aretinal disease 610 $avitamin D 610 $aGLP-1 610 $asuperoxide dismutase 610 $abiomarkers of diabetic retinopathy 610 $ametabolic memory 610 $atear film 610 $aaqueous humor 610 $avitreous humor 610 $amitochondria 610 $aredox 610 $aphotoreceptor 610 $aglycation 610 $aaging 610 $aglyoxalase 615 7$aMedicine 700 $aOrtega$b A?ngel Luis$4edt$01294143 702 $aOrtega$b A?ngel Luis$4oth 906 $aBOOK 912 $a9910557134903321 996 $aOxidative Stress in Diabetic Retinopathy$93022924 997 $aUNINA