LEADER 05633nam 2201561z- 450 001 9910557124003321 005 20231214133254.0 035 $a(CKB)5400000000040814 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/68416 035 $a(EXLCZ)995400000000040814 100 $a20202105d2021 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPLGA Based Drug Carrier and Pharmaceutical Applications 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021 215 $a1 electronic resource (328 p.) 311 $a3-0365-0220-3 311 $a3-0365-0221-1 330 $aPoly(lactic-co-glycolic acid) (PLGA) is one of the most successful polymers used for producing therapeutic devices, such as drug carriers (DC). PLGA is one of the few polymers that the Food and Drug Administration (FDA) has approved for human administration due to its biocompatibility and biodegradability. In recent years, DC produced with PLGA has gained enormous attention for its versatility in transporting different type of drugs, e.g., hydrophilic or hydrophobic small molecules, or macromolecules with a controlled drug release without modifying the physiochemical properties of the drugs. These drug delivery systems have the possibility/potential to modify their surface properties with functional groups, peptides, or other coatings to improve the interactions with biological materials. Furthermore, they present the possibility to be conjugated with specific target molecules to reach specific tissues or cells. They are also used for different therapeutic applications, such as in vaccinations, cancer treatment, neurological disorder treatment, and as anti-inflammatory agents. This book aims to focus on the recent progress of PLGA as a drug carrier and their new pharmaceutical applications. 606 $aMedicine$2bicssc 610 $aPLGA 610 $ananoscaled drug delivery 610 $aLED 610 $acancer 610 $aserum stability 610 $areactive oxygen species 610 $acellular uptake 610 $aterahertz spectroscopy 610 $amicrospheres 610 $adrug delivery 610 $aformulation development 610 $amolecular mobility 610 $avitamin E 610 $atocopherol 610 $aPLA 610 $acore-shell nanoparticles 610 $acontrolled drug release 610 $aBMP-2 610 $aPLGA nanoparticles 610 $aPluronic F68 610 $aoxaliplatin 610 $ahydrogel 610 $aintra-abdominal anti-adhesion barrier 610 $acolorectal cancer 610 $aexperimental design 610 $afractional factorial design 610 $aO6-methylguanine DNA methyltransferase (MGMT) protein 610 $aglioblastoma multiforme 610 $asmart nanocarriers 610 $afolic acid 610 $averteporfin 610 $acisplatin 610 $aSKOV-3 cells 610 $aCHO-K1 cells 610 $aelectroporation 610 $atheranostic cargo 610 $adouble emulsion approach 610 $aNSAIDs 610 $apolymeric film 610 $atopical drug delivery 610 $atrolamine salicylate 610 $atriamcinolone acetonide 610 $amicrocrystal 610 $aPLGA microsphere 610 $alocal delivery 610 $aspray-drying technique 610 $aintra-articular injection 610 $ajoint retention 610 $asystemic exposure 610 $agadolinium 610 $adrug release 610 $apolymeric nanocarrier 610 $asorafenib 610 $atheranostic nanoparticles 610 $aPLGA-PEG 610 $ananoparticles 610 $aplatelet 610 $aactivation 610 $aaggregation 610 $abinding 610 $auptake 610 $atissue engineering 610 $aHuntington's disease 610 $asiRNA 610 $amicrocarriers 610 $amesenchymal stromal cells 610 $adrug delivery systems 610 $amicrofluidics 610 $amicroparticles 610 $aBMP-2-microspheres 610 $ahydrogel system 610 $a17-?estradiol release 610 $abone regeneration 610 $aosteoporosis 610 $apoly-lactide-co-glycolide 610 $apolylactic acid 610 $aalginate 610 $aophthalmic drug delivery 610 $adexamethasone 610 $aPLGA-NPs 610 $ananomedicine 610 $agastrointestinal tract 610 $apaclitaxel 610 $ain vivo imaging 610 $acontrolled release 610 $arisperidone 610 $amicrocapsules 610 $aoleogels 610 $aelectron microscopy 610 $athree-dimensional X-ray imaging 610 $anano-CT 610 $abiodegradable polymers 610 $ahydroxy-stearic acid 610 $aPLGA nanocapsules 610 $amagnetic resonance imaging 610 $aphotoluminescence 610 $amagnetic targeting 610 $amultimodal imaging 610 $atheranostics 610 $asilicon 610 $amicrosphere 615 7$aMedicine 700 $aPereira$b Maria Carmo$4edt$01318423 702 $aLoureiro$b Joana$4edt 702 $aPereira$b Maria Carmo$4oth 702 $aLoureiro$b Joana$4oth 906 $aBOOK 912 $a9910557124003321 996 $aPLGA Based Drug Carrier and Pharmaceutical Applications$93033226 997 $aUNINA