LEADER 03317nam 2200817z- 450 001 9910557107603321 005 20210501 035 $a(CKB)5400000000040971 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69424 035 $a(oapen)doab69424 035 $a(EXLCZ)995400000000040971 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aEnzyme Inhibitor from Marine Organisms 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (130 p.) 311 08$a3-03943-783-6 311 08$a3-03943-784-4 330 $aMarine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet's surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from marine environments have been described. This is, and will be, a promising source of candidate compounds in pharma research and chemical biology. In recent years, a number of novel techniques have been introduced to the field and it has become easier to actually (bio-)prospect compounds such as enzyme inhibitors. Those novel compounds then need to be characterized and evaluated in comparison to well-known representatives. This Special Issue focuses on the description of novel enzyme inhibitors of marine origin, including bioprospecting, omic approaches, and structural and mechanistic aspects. 606 $aResearch & information: general$2bicssc 610 $aACE inhibitory peptide 610 $aacetylcholinesterase 610 $aAlzheimer's disease 610 $aasperchalasine 610 $aBACE1 610 $abioactives 610 $adrug development 610 $aenzyme inhibition 610 $afunctional annotation 610 $aGH109 ?-N-acetylgalactosaminidase 610 $aGH36 ?-galactosidase 610 $ain silico docking 610 $ainactivation 610 $ainhibitor 610 $akinase inhibitors 610 $amacroalgae 610 $amarine bacteria 610 $amarine fish 610 $amarine fungi 610 $amarine natural products 610 $amarine sponges 610 $amolecular docking 610 $amonanchomycalin B 610 $amonanhocidin A 610 $aMycosphaerella sp. 610 $anatural products 610 $anormonanhocidin A 610 $aoptimization 610 $apentacyclic guanidine alkaloids 610 $aphlorotannins 610 $aprotease 610 $apurification 610 $asecondary metabolites 610 $aslow-binding irreversible inhibitor 610 $asponge Monanchora pulchra 610 $astructural identification 610 $astructure-function relation 610 $aUlva intestinalis 610 $aUlva ohnoi 610 $a?-glucosidase 615 7$aResearch & information: general 700 $aTischler$b Dirk$4edt$01064503 702 $aTischler$b Dirk$4oth 906 $aBOOK 912 $a9910557107603321 996 $aEnzyme Inhibitor from Marine Organisms$93036291 997 $aUNINA