LEADER 03129nam 2200721z- 450 001 9910557107403321 005 20210501 035 $a(CKB)5400000000040973 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69367 035 $a(oapen)doab69367 035 $a(EXLCZ)995400000000040973 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aApheresis in Neurological Disorders 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (174 p.) 311 08$a3-03943-585-X 311 08$a3-03943-586-8 330 $aApheresis refers to an extracorporeal therapy which aims at removing pathological constituents from the patients' blood. Due to the development of new techniques as well as the discovery of novel autoimmune antibodies, it is increasingly recognized as an important therapeutic option for a variety of autoimmune-mediated neurological disorders, including multiple sclerosis, myasthenia gravis, autoimmune encephalitis, Guillain-Barre? syndrome, and many others. Therapeutic plasma exchange (TPE) constitutes the standard method of apheresis for most indications, while immunoadsorption (IA) offers a more specific, low-risk alternative. Both methods aim at removing auto-antibodies from the blood. Evidence for most neurological diseases is still low. Interestingly, more recent developments suggest that apheresis is not limited to the removal of autoantibodies but may also be useful in neurodegenerative and possibly even in acute vascular disorders. 606 $aMedicine and Nursing$2bicssc 610 $aacute relapsing multiple sclerosis 610 $aAlzheimer's clinical syndrome 610 $aantibody 610 $aapheresis 610 $aautoantibodies 610 $aautoimmune encephalitis 610 $achronic inflammatory demyelinating polyneuropathy 610 $aclass IV 610 $aCRP 610 $adementia 610 $aGuillain-Barre? syndrome 610 $aimmunoadsorption 610 $ainflammation 610 $aInflammatory neuropathy 610 $alimbic encephalitis 610 $amultiple sclerosis 610 $aMyalgic Encephalomyelitis/Chronic Fatigue Syndrome 610 $an/a 610 $aneurological diseases 610 $aNMDAR (N-Methyl-D-Aspartat) 610 $aoptic neuritis 610 $aparaneoplastic 610 $aparanodal antibodies 610 $aplasma exchange 610 $aplasmapheresis 610 $arelapse 610 $aß2 adrenoreceptor autoantibody 610 $asteroids 610 $astroke 610 $atherapeutic apheresis 610 $atherapeutic plasma exchange 610 $a?1-Adrenergic receptor 615 7$aMedicine and Nursing 700 $aDorst$b Johannes$4edt$01294139 702 $aDorst$b Johannes$4oth 906 $aBOOK 912 $a9910557107403321 996 $aApheresis in Neurological Disorders$93022920 997 $aUNINA