LEADER 04352nam 2200673 450 001 9910781786603321 005 20230125183844.0 010 $a1-4426-8988-9 010 $a1-4426-6015-5 024 7 $a10.3138/9781442689886 035 $a(CKB)2550000000043200 035 $a(EBL)3275959 035 $a(SSID)ssj0000539605 035 $a(PQKBManifestationID)12181671 035 $a(PQKBTitleCode)TC0000539605 035 $a(PQKBWorkID)10580054 035 $a(PQKB)10402423 035 $a(CaBNVSL)slc00227101 035 $a(CEL)436446 035 $a(MiAaPQ)EBC3275959 035 $a(MiAaPQ)EBC4672725 035 $a(DE-B1597)465162 035 $a(OCoLC)944176490 035 $a(OCoLC)999366214 035 $a(DE-B1597)9781442689886 035 $a(Au-PeEL)EBL4672725 035 $a(CaPaEBR)ebr11258379 035 $a(OCoLC)958580144 035 $a(EXLCZ)992550000000043200 100 $a20160923h20102010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aNorthrop Frye's writings on Shakespeare and the Renaissance /$fedited by Troni Y. Grande and Garry Sherbert 210 1$aToronto, [Ontario] ;$aBuffalo, [New York] ;$aLondon, [England] :$cUniversity of Toronto Press,$d2010. 210 4$d©2010 215 $a1 online resource (857 p.) 225 0 $aCollected Works of Northrop Frye ;$vVolume 28 300 $aIncludes index. 311 $a1-4426-4168-1 320 $aIncludes bibliographical references and index. 327 $tFrontmatter -- $tContents -- $tPreface -- $tCredits -- $tAbbreviations -- $tIntroduction -- $t1. The Argument of Comedy -- $t2. Don Quixote -- $t3. Comic Myth in Shakespeare -- $t4. Characterization in Shakespearean Comedy -- $t5. Molière's Tartuffe -- $t6. Introduction to Shakespeare's Tempest -- $t7. The Structure of Imagery in The Faerie Queene -- $t8. Shakespeare's Experimental Comedy -- $t9. Toast to the Memory of Shakespeare -- $t10. The Tragedies of Nature and Fortune -- $t11. How True a Twain -- $t12. Recognition in The Winter's Tale -- $t13. A Natural Perspective: The Development of Shakespearean Comedy and Romance -- $t14. Shakespeare and the Modern World -- $t15. Nature and Nothing -- $t16. Fools of Time -- $t17. General Editor's Introduction to Shakespeare Series -- $t18. Shakespeare's The Tempest -- $t19. Il Cortegiano -- $t20. The Myth of Deliverance -- $t21. Something Rich and Strange: Shakespeare's Approach to Romance -- $t22. The Stage Is All the World -- $t23. Northrop Frye on Shakespeare -- $t24. Speech on Acceptance of the Governor General's Award for Northrop Frye on Shakespeare -- $t25. Natural and Revealed Communities -- $t26. Foreword to Unfolded Tales -- $tNotes -- $tEmendations -- $tIndex 330 $aThis collection of Northrop Frye's writings on Shakespeare and the Renaissance spans forty years of his career as a university teacher, public critic, and major theorist of literature and its cultural functions. Extensive annotations and an in-depth critical introduction demonstrate Frye's wide-ranging knowledge of Renaissance culture, the pivotal place of the Renaissance in his oeuvre, his impact on Renaissance criticism and on the Stratford Festival, and his continuing importance as a literary theorist.This volume brings together Frye's extensive writings on Shakespeare and other Renaissance writers (excluding Milton, who is featured in other volumes), and includes major articles, introductions, public lectures, and four previously published books on Shakespeare. Frye's insightful analyses offer not just a formidable knowledge of Renaissance culture but also a transformative experience, moving the reader imaginatively towards an experience of created reality. 606 $aEuropean literature$yRenaissance, 1450-1600$xHistory and criticism 615 0$aEuropean literature$xHistory and criticism. 676 $a822.3/3 700 $aFrye$b Northrop, $0131719 702 $aGrande$b Troni Y.$f1960- 702 $aSherbert$b Garry$f1957- 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 852 0$3Cover image:$uhttp://celarc.ca/covers/436/436446.jpg 906 $aBOOK 912 $a9910781786603321 996 $aNorthrop Frye's writings on Shakespeare and the Renaissance$93760365 997 $aUNINA LEADER 04581nam 2201297z- 450 001 9910557105803321 005 20210501 035 $a(CKB)5400000000040989 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/68966 035 $a(oapen)doab68966 035 $a(EXLCZ)995400000000040989 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aMetastatic Progression and Tumour Heterogeneity 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 online resource (312 p.) 311 08$a3-03928-853-9 311 08$a3-03928-854-7 330 $aImproved understanding of the cellular and molecular makeup of tumors in the last 30 years has unraveled a previously unexpected level of heterogeneity among tumor cells as well as within the tumor microenvironment. The concept of tumor heterogeneity underlines the realization that different tumors can display significant differences in their genomic content as well as in their overall behavior. Our capacity to better understand the heterogeneous make up of tumors has very important consequences on our ability to design efficient therapeutic strategies to improve patient survival. This book highlights several aspects of tumor heterogeneity in the context of metastatic development and summarize some of the challenges posed by heterogeneity for tumor diagnostics and therapeutic management of tumors. 606 $aMedicine and Nursing$2bicssc 610 $a3D cultures 610 $aacidosis 610 $aADH 610 $aangiocrine factor 610 $abeta-catenin paradox 610 $abiomechanics 610 $abreast cancer 610 $acarbonic anhydrase 610 $acell fate 610 $acellular heterogeneity 610 $acirculating tumor cells 610 $acirculating tumor cells (CTCs) 610 $aclear cell renal cell carcinoma 610 $aclonality 610 $acollective and single-cell migration 610 $acolon cancer 610 $acolorectal cancer 610 $aCTC-clusters 610 $aDCIS 610 $adeficient mismatch repair 610 $aEMT 610 $aendometrial carcinoma 610 $aepigenetics 610 $aepithelial mesenchymal plasticity 610 $aepithelial-to-mesenchymal transition 610 $aesophageal squamous cell carcinoma 610 $aextracellular vesicles 610 $agene expression 610 $agenomics 610 $aheterogeneity 610 $ahybrid E/M 610 $ahyperpolarized 13C MRI 610 $aimmune checkpoints 610 $aimmune microenvironment 610 $aimmunotherapy 610 $ainterstitial pH 610 $aintra-tumour heterogeneity 610 $aintratumor heterogeneity 610 $alactic acid 610 $amagnetic resonance imaging 610 $amammary gland 610 $ametaplastic carcinoma 610 $ametastasis 610 $ametastatic niche 610 $amicrosatellite instability 610 $amiRNA expression 610 $amultisite tumor sampling 610 $amutation 610 $anatural killer cells 610 $anuclear medicine 610 $aorganoids 610 $apancreatic cancer 610 $aPET 610 $aphenotypic plasticity 610 $aPI3K/AKT pathway 610 $aplasticity 610 $apositron emission tomography 610 $aprecision medicine 610 $aradiomics 610 $aradiopharmaceuticals 610 $areview 610 $asignaling 610 $asingle-cell analysis 610 $asingle-cell RNAseq 610 $asubclonal diversity 610 $aSUV 610 $atarget discovery 610 $atargeted therapy 610 $aTP53 610 $atreatment resistance 610 $atumor ecology 610 $atumor endothelial cell 610 $atumor evolution 610 $atumor heterogeneity 610 $atumor microenvironment 610 $atumor mutation burden 610 $auterine carcinosarcoma 610 $aWnt signaling 615 7$aMedicine and Nursing 700 $aHollande$b Fred$4edt$01327820 702 $aMerino$b Delphine$4edt 702 $aHollande$b Fred$4oth 702 $aMerino$b Delphine$4oth 906 $aBOOK 912 $a9910557105803321 996 $aMetastatic Progression and Tumour Heterogeneity$93038137 997 $aUNINA