LEADER 03781nam 2201129z- 450 001 9910557104703321 005 20231214133610.0 035 $a(CKB)5400000000041000 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69082 035 $a(EXLCZ)995400000000041000 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPathogenesis and Treatment of Chronic Pruritus 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 electronic resource (144 p.) 311 $a3-03943-100-5 311 $a3-03943-101-3 330 $aThis Special Edition Issue on the ?Pathogenesis and Treatment of Chronic Pruritus? contains an overview of various known causes of chronic pruritus and emerging therapeutics. Chronic pruritus is an itch that lasts longer than six weeks, and is associated with a variety of dermatologic, systemic, neurologic, and psychiatric etiologies. Itch negatively impacts patient quality of life, and has devastating psychosocial consequences. The manuscripts published in this Special Issue are also a showcase of the current understanding of the pathogenesis of chronic pruritus, along with its epidemiology, diagnostic workup, and therapeutic approaches used to treat chronic pruritus. A special focus is also placed on prurigo nodularis, a severely pruritic chronic inflammatory skin disease. 606 $aMedicine$2bicssc 610 $adupilumab 610 $aIL-4 610 $aIL-13 610 $apruritus 610 $achronic pruritus of unknown origin 610 $aprurigo nodularis 610 $auremic pruritus 610 $alichen planus 610 $aeosinophilic dermatosis of hematologic malignancy 610 $achronic pruritus 610 $amirtazapine 610 $achronic 610 $aitch 610 $arefractory 610 $atreatment 610 $anoradrenergic 610 $aserotonergic 610 $aantihistaminergic 610 $aantidepressant 610 $askin 610 $aatopic dermatitis 610 $aceramide 610 $apine tar 610 $adrug-induced 610 $amedication-related 610 $aepidemiology 610 $ainpatient 610 $adisease burden 610 $anational inpatient sample 610 $amedical dermatology 610 $asystematic review 610 $aprurigo 610 $anodularis 610 $aatopic 610 $adermatitis 610 $arace 610 $agender 610 $acomorbidities 610 $ademographics 610 $apediatric 610 $achildren 610 $amalignancy 610 $acancer 610 $aneoplasm 610 $aion channels 610 $acell signaling 610 $aCav3.2 calcium channel 610 $aRT-PCR 610 $awounds 610 $aitch in wounds 610 $aitch management 610 $aaprepitant 610 $aerlotinib 610 $aEGFR 610 $aepidermal growth factor receptor 610 $aNK1R 610 $aneurokinin1-receptor 610 $amycosis fungoides 610 $apsoriasis 610 $aassociations 610 $alymphomatoid papulosis 610 $alymphoma 610 $aracial differences 610 $anodular prurigo 610 $aneuropathy 610 $atherapeutic 610 $apathogenesis 615 7$aMedicine 700 $aKwatra$b Shawn G$4edt$01296133 702 $aKwatra$b Shawn G$4oth 906 $aBOOK 912 $a9910557104703321 996 $aPathogenesis and Treatment of Chronic Pruritus$93023793 997 $aUNINA