LEADER 03676nam  2200973z- 450 
001 9910557102403321
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035   $a(CKB)5400000000041023
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69447
035   $a(oapen)doab69447
035   $a(EXLCZ)995400000000041023
100   $a20202105d2020      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aThe Advances and Applications of Optogenetics
210   $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020
215   $a1 online resource (164 p.)
311 08$a3-03943-673-2 
311 08$a3-03943-674-0 
330   $aThis book provides an update for the rapidly developing technology known as "optogenetics", which is the use of genetically encoded light-sensitive molecular elements (usually derived from lower organisms) to control or report various physiological and biochemical processes within the cell. Two ongoing clinical trials use optogenetic tools for vision restoration, and optogenetic strategies have been suggested as novel therapies for several neurological, psychiatric and cardiac disorders. This Special Issue comprises two reviews and seven experimental papers on different types of light-sensitive modules widely used in optogenetic studies. These papers demonstrate the efficiency and versatility of optogenetics and are expected to be equally relevant for advanced users and beginners considering using optogenetic tools in their research.
606   $aBiology, life sciences$2bicssc
606   $aResearch and information: general$2bicssc
610   $aall-optical electrophysiology
610   $aAsLOV2
610   $aazobenzene
610   $aBLUF
610   $acalcium
610   $acalcium sensor
610   $achannelrhodopsin
610   $achannelrhodopsin-2
610   $achannelrhodopsins
610   $aChlamydomonas reinhardtii
610   $aCTMD method, residual hydrophobic mismatch
610   $aDC gate
610   $aelectrophysiology
610   $aenergy of membrane deformation
610   $aflash photolysis
610   $ahippocampal neurons
610   $ahybrid QM/MM simulation
610   $aintracellular trafficking
610   $aion channel
610   $aion channels
610   $aLEXY
610   $alight stimulation
610   $aLINuS
610   $aLOV domains
610   $amembrane current
610   $amembrane potential
610   $amembrane-protein interaction
610   $amicrobial rhodopsin
610   $amicrobial rhodopsins
610   $aMIP
610   $amodular domain
610   $amolecular dynamics simulations
610   $aneuroscience
610   $aneurotransmitters
610   $aoptogenetic tools
610   $aoptogenetics
610   $aOptogenetics
610   $ap53
610   $aphotocontrol
610   $aphotoreceptor
610   $aphotoswitch
610   $aphotoswitching
610   $aPMI
610   $aprotein-protein interaction
610   $aresonance Raman
610   $asignaling
610   $asodium
610   $atwo-photon
610   $avoltage sensor
615  7$aBiology, life sciences
615  7$aResearch and information: general
700   $aGovorunova$b Elena G$4edt$01320353
702   $aSineshchekov$b Oleg A$4edt
702   $aGovorunova$b Elena G$4oth
702   $aSineshchekov$b Oleg A$4oth
906   $aBOOK
912   $a9910557102403321
996   $aThe Advances and Applications of Optogenetics$93034178
997   $aUNINA