LEADER 04058nam 2200397 450 001 9910553076503321 005 20230516225439.0 035 $a(CKB)5860000000016677 035 $a(NjHacI)995860000000016677 035 $a(EXLCZ)995860000000016677 100 $a20230516d2022 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aXenopus $efrom basic biology to disease models in the genomic era /$fedited by Abraham Fainsod, Sally A. Moody 210 1$aBoca Raton :$cTaylor & Francis,$d2022. 210 4$dİ2022 215 $a1 online resource (360 pages) 311 $a0-367-50534-7 320 $aIncludes bibliographical references and index. 327 $aSection I. -- 1. A quick history of Xenopus. -- 2. The study of cell division controla and DNA replication in Xenopus egg extracts. -- 3. Maternal gene control of embryogenesis: germ cell determination and germ layer formation. -- 4. Signaling components in dorsal-ventral patterning and the Organizer. -- 5. Signaling pathways in anterior-posterior patterning. -- 6. Wnt signaling in tissue differentiation and morphogenesis. -- 7. Multiple functions of Notch signaling during early embryogenesis. -- 8. The development and evolution of the vertebrate neural crest: Insights from Xenopus. -- 9. The use of Xenopus oocytes to study the biophysics and pharmacological properties of receptors and channels. -- Section II. -- 10. The continuing evolution of the Xenopus genome. -- 11. Dynamics of chromatin remodeling during Xenopus development. -- 12. Gene regulatory networks controlling Xenopus embryogenesis. -- 13. The development of high-resolution proteomic analyses in Xenopus. -- 14. Advances in genome editing tools. -- Section III. -- 15. Formation of the left-right axis: insights from the Xenopus model. -- 16. Discovering the function of congenital heart disease genes. -- 17. Craniofacial development and disorders - contributions of Xenopus. -- 18. Modeling digestive and respiratory system development and disease in Xenopus. -- 19. Functional neurobiology and insights into human disease. -- 20. Leaping towards the understanding of spinal cord regeneration. -- 21. Studying tumor formation and regulation in Xenopus. -- 22. Xenopus: a model to study natural genetic variation and its disease implications. -- 23. Using Xenopus to understand pluripotency and reprogram cells for therapeutic use. Maternal gene control of embryogenesis. -- Chapter 8: Sex determination in Xenopus. -- Section II: Gene Discovery and Disease. -- Chapter 9: Xenopus and the discovery of developmental genes. -- Chapter 10: Systems Biology of Xenopus Embryogenesis. -- Chapter 11: Gene regulatory networks in craniofacial development. -- Chapter 12: Using Xenopus to discover regulation of GI development and disease. -- Chapter 13: Using Xenopus to discover the function of congenital heart disease genes. -- Chapter 14: Using Xenopus to discover the function of congenital kidney disease genes. -- Chapter 15: Using Xenopus to study genes involved in cancers. -- Section III: Evolution. Chapter 16: Evolution of amphibians. Chapter 17: Evolution of Xenopus communication. Chapter 18: Evolution of the immune system . -- Chapter 19: Evolution of the left-right axis. -- Chapter 20: Evolution of the Xenopus genome. 330 $a"Xenopus is unique among the model animals used in the biology. Several books of protocols used Xenopus. Missing is a book taking an historical perspective documenting cell and developmental discoveries and illustrating how Xenopus contributes to the understanding of genes. These topics will be covered in the proposed book"-- Provided by publisher. 517 $aXenopus 606 $aXenopus 615 0$aXenopus. 676 $a597.8654 702 $aFainsod$b Abraham 702 $aMoody$b Sally A. 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910553076503321 996 $aXenopus$92986973 997 $aUNINA