LEADER 00401nam##22001337##450# 001 9910551697003321 010 $a9788878702370 100 $a########d########u##y0engy50####ba 105 0 $a########00### 200 1 $aL'assoluto e la storia : Oriente e Occidente a confronto / Nicola Mapelli. 700 $aMapelli, Nicola.$0600942 912 $a9910551697003321 996 $aL'assoluto e la storia$92428910 997 $aUNINA LEADER 04422nam 22005775 450 001 9910279579003321 005 20200706053824.0 010 $a4-431-56603-1 024 7 $a10.1007/978-4-431-56603-8 035 $a(CKB)3840000000348063 035 $a(MiAaPQ)EBC5287194 035 $a(DE-He213)978-4-431-56603-8 035 $a(PPN)22463691X 035 $a(EXLCZ)993840000000348063 100 $a20180208d2017 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aEvolution of the Human Genome I $eThe Genome and Genes /$fedited by Naruya Saitou 205 $a1st ed. 2017. 210 1$aTokyo :$cSpringer Japan :$cImprint: Springer,$d2017. 215 $a1 online resource (305 pages) $cillustrations 225 1 $aEvolutionary Studies,$x2509-484X 311 $a4-431-56601-5 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aPreface -- Part I: Overview of the Human Genome -- Chapter 1: Human evolution and human genome at a glance -- Chapter 2: Rubbish DNA: The functionless fraction of the human genome -- Chapter 3: GC content heterogeneity -- Chapter 4: Protein-coding and non-coding RNA genes -- Chapter 5: Duplicated genes -- Chapter 6: Recombination.-Chapter 7: CNVs and microsatellite DNA polymorphism.-Part II: The Human Genome Viewed through Genes.-Chapter 8: Genes on X and Y chromosomes -- Chapter 9: Human Leukocyte Antigen (HLA) region in human population studies.-Chapter 10: Evolution of genes for color vision and the chemical senses in primates.-Chapter 11: Global landscapes of human phenotypic variation in inherited traits -- Chapter 12: Transcription factor genes -- Chapter 13: Genetics of diabetes: are they thrifty genotype? -- Chapter 14: Disease-related genes from population genetic aspect and their functional significance -- Chapter 15: Microbe genomes associated with human body.-Index. 330 $aThis book reviews the human genome from an evolutionary perspective. No such book has ever been published before, although there are many books on human genomes. There are two parts in this book: Overview of the Human Genome (Part I) and The Human Genome Viewed through Genes (Part II). In Part I, after a brief review of human evolution and the human genome (by Naruya Saitou), chapters on rubbish or junk DNA (by Dan Graur), GC content heterogeneity (by Satoshi Oota), protein coding and RNA coding genes (by Tadashi Imanishi), duplicated genes (by Takashi Kitano), recombinations (by Montanucci and Bertranpetit), and copy number variations including microsatellites (by Naoko Takezaki) are discussed. Readers can obtain various new insights on the human genome from this part. In Part II, genes in X and Y chromosomes (by Yoko Satta and others), HLA genes (by Timothy A. Jinam), opsin genes (by Shoji Kawamura and Amanda D. Melin), genes related to phenotypic variations (by Ryosuke Kimura), transcription factors (by Mahoko Takahashi and So Nakagawa), diabetes-related genes (by Ituro Inoue), disease genes in general (by Ituro Inoue and Hirofumi Nakaoka), and microbial genomes (by Chaochun Wei) are discussed. The human genome sequences were determined in 2004, and after more than 10 years we are now beginning to understand the human genome from an evolutionary point of view. This book furnishes readers with a good summary of current research in the field. 410 0$aEvolutionary Studies,$x2509-484X 606 $aEvolution (Biology) 606 $aHuman genetics 606 $aAnthropology 606 $aEvolutionary Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L21001 606 $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008 606 $aAnthropology$3https://scigraph.springernature.com/ontologies/product-market-codes/X12000 615 0$aEvolution (Biology) 615 0$aHuman genetics. 615 0$aAnthropology. 615 14$aEvolutionary Biology. 615 24$aHuman Genetics. 615 24$aAnthropology. 676 $a611.01816 702 $aSaitou$b Naruya$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910279579003321 996 $aEvolution of the Human Genome I$92084613 997 $aUNINA