LEADER 04886nam 22007095 450 001 9910544851403321 005 20251113211346.0 010 $a3-030-72702-5 024 7 $a10.1007/978-3-030-72702-4 035 $a(MiAaPQ)EBC6888374 035 $a(Au-PeEL)EBL6888374 035 $a(CKB)21251226200041 035 $a(PPN)260830070 035 $a(OCoLC)1302010865 035 $a(DE-He213)978-3-030-72702-4 035 $a(EXLCZ)9921251226200041 100 $a20220214d2022 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aColon Cancer Diagnosis and Therapy Vol. 3 /$fedited by Dhananjay Shukla, Naveen Kumar Vishvakarma, Ganji Purnachandra Nagaraju 205 $a1st ed. 2022. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2022. 215 $a1 online resource (459 pages) $cillustrations 225 1 $aBiomedical and Life Sciences Series 311 08$aPrint version: Shukla, Dhananjay Colon Cancer Diagnosis and Therapy Vol. 3 Cham : Springer International Publishing AG,c2022 9783030727017 320 $aIncludes bibliographical references and index. 327 $aChapter 1. Role of chemokines in colorectal cancer -- Chapter 2. Extracellular vesicles in colorectal cancer growth, metastasis, diagnosis and therapy -- Chapter 3. Epigenetic regulation of colorectal cancer (CRC) -- Chapter 4. Mechanistic exploration and therapeutic management of colon cancer metastasis -- Chapter 5. Chemoresistance in colon malignancies -- Chapter 6. Targeting pathogenic inflammation for therapeutic intervention against colon cancer -- Chapter 7. Role of tumor associated macrophages in colon cancer progression and its therapeutic targeting -- Chapter 8. Therapeutic intervention of signaling pathways in colorectal cancer -- Chapter 9. Advances in chemoradiotherapy for treatment of colon cancer -- Chapter 10. Cytotoxic and chemopreventive activity of polyphenols and their derivatives in colon cancer -- Chapter 11. Prevention and management of colon cancer by nutritional intervention -- Chapter 12. Development of RNA based medicine for colorectal cancer -- Chapter 13. Role offood additives and intestinal microflora in colorectal cancer -- Chapter 14. Probiotics in colon cancer -- Chapter 15. Bacterial cancer therapy -- Chapter 16. Antineoplastic effects of curcumin against colorectal cancer -- Chapter 17. Cyanobacterial secondary metabolite -- Chapter 18. Clinical significance of genetic variants in colon cancer. 330 $aColorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis. This book is the third of three volumes on recent developments in colorectal diagnosis and therapy. Each volume can be read on its own, or together. Each volume focuses on different novel therapeutic advances, biomarkers, and identifies therapeutic targets for treatment. Written by leading international experts in the field, coverage addresses the role of diet habits and lifestyle in reducing gastrointestinal disorders and incidence of CRC. Chapters discuss current and future diagnostic and therapeutic options for colorectal cancer patients, focusing on immunotherapeutics, nanomedicine, biomarkers, and dietary factors for the effective management of colon cancer. 410 0$aBiomedical and Life Sciences Series 606 $aCancer$xTreatment 606 $aCancer 606 $aMedical screening 606 $aImmunotherapy 606 $aBiochemical markers 606 $aCancer Therapy 606 $aCancer Screening 606 $aImmunotherapy 606 $aBiomarkers 615 0$aCancer$xTreatment. 615 0$aCancer. 615 0$aMedical screening. 615 0$aImmunotherapy. 615 0$aBiochemical markers. 615 14$aCancer Therapy. 615 24$aCancer Screening. 615 24$aImmunotherapy. 615 24$aBiomarkers. 676 $a616.99 676 $a616.994347 702 $aShukla$b Dhananjay 702 $aVishvakarma$b Naveen Kumar 702 $aNagaraju$b Ganji Purnachandra 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910544851403321 996 $aColon Cancer Diagnosis and Therapy Vol. 3$94462615 997 $aUNINA