LEADER 05464nam 22008175 450 001 9910544848903321 005 20240426153724.0 010 $a9783030930561$b(electronic bk.) 010 $z9783030930554 024 7 $a10.1007/978-3-030-93056-1 035 $a(MiAaPQ)EBC6888377 035 $a(Au-PeEL)EBL6888377 035 $a(OCoLC)1298391231 035 $a(CKB)21251226500041 035 $a(DE-He213)978-3-030-93056-1 035 $a(PPN)260826855 035 $a(EXLCZ)9921251226500041 100 $a20220214d2022 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aOrganoid Technology for Disease Modelling and Personalized Treatment /$fedited by Badrul Hisham Yahaya 205 $a1st ed. 2022. 210 1$aCham :$cSpringer International Publishing :$cImprint: Humana,$d2022. 215 $a1 online resource (209 pages) 225 1 $aStem Cell Biology and Regenerative Medicine,$x2196-8993 ;$v71 311 08$aPrint version: Yahaya, Badrul Hisham Organoid Technology for Disease Modelling and Personalized Treatment Cham : Springer International Publishing AG,c2022 9783030930554 320 $aIncludes bibliographical references. 327 $aChapter 1. The hope and the hype in organoid technology in regenerative medicine (Badrul Hisham Yahaya) -- Chapter 2. Pluripotent stem cell derived and adult-tissue-derived organoid (Tiago G. Fernandes) -- Chapter 3. Generation of human organoid for 3D stem cell culture Hans Clevers -- Chapter 4. Organogenesis in a dish: Organ developmental study using organoid technology (Kursad Tuksen) -- Chapter 5. Disease modelling using patient-derived organoid (Narisorn Kitiyanant) -- Chapter 6. Tumor organoid as a model to study cancer microenvironment (Ahmad Faried) -- Chapter 7. Gene-editing in organoid to improve understanding of human disease (Yinming Liang) -- Chapter 8. Organoid culture as a good model to study lung development (Mitsuru Morimoto) -- Chapter 9. Organoid as good model for respiratory diseases (Badrul Hisham Yahaya).-Chapter 10. In vitro 3D model on reproductive system (Ruttachuk Rungsiwiwut) -- Chapter 11. Modelling of neuronal organoid: The way forward and challenges (Juntang Lin) -- Chapter 12. Generation of cardiac organoid in early heart organogenesis (Tan Jun Jie) -- Chapter 13. Neural Crest-Derived Stem Cells in organoid development for neurodegenerative disease modelling (Darius Widera) -- Chapter 14. Organoid for drug discovery and personalized treatment (Toshio Takahashi) -- Chapter 15. Ethical concern on patient-derived organoid (Phuc Van Pham). 330 $aOrganoid Technology for Disease Modelling and Personalised Treatment provides a comprehensive overview of current knowledge of the organoid as a human-organ-in-a-dish, a powerful new technology for studying fundamental aspects of human organ development and disease progression in the search for drugs for personalised treatment. This preclinical tool is extensively being utilised as a model for studying human diseases in a dish, which is critical for accurate predictive modelling in precision medicine. The chapters in this book introduces readers to the numerous applications of organoids in various fields of study, as well as ethical considerations associated with organoids. In stem cell biology and regenerative medicine, where chimaera research, biomaterials for tissue vascularisation, gene-editing technologies, and their use in clinical procedures especially issues related to ethical concern over the use of human organoids have gotten much attention. Organoid Technology for Disease Modelling and Personalised Treatment is an excellent resource for in-depth research on one of the most interesting and significant topics in stem cell and regenerative medicine. This book's chapter collection covers a fresh viewpoint on organoid technology that scholars will require reading. 410 0$aStem Cell Biology and Regenerative Medicine,$x2196-8993 ;$v71 606 $aStem cells 606 $aRegenerative medicine 606 $aDiseases$xAnimal models 606 $aMedicine$xResearch 606 $aBiology$xResearch 606 $aStem Cell Biology 606 $aRegenerative Medicine and Tissue Engineering 606 $aDisease Models 606 $aTranslational Research 606 $aMedicina regenerativa$2thub 606 $aCčl·lules mare$2thub 606 $aTerąpia cel·lular$2thub 606 $aMedicina personalitzada$2thub 606 $aŅrgans (Anatomia)$2thub 608 $aLlibres electrņnics$2thub 615 0$aStem cells. 615 0$aRegenerative medicine. 615 0$aDiseases$xAnimal models. 615 0$aMedicine$xResearch. 615 0$aBiology$xResearch. 615 14$aStem Cell Biology. 615 24$aRegenerative Medicine and Tissue Engineering. 615 24$aDisease Models. 615 24$aTranslational Research. 615 7$aMedicina regenerativa 615 7$aCčl·lules mare 615 7$aTerąpia cel·lular 615 7$aMedicina personalitzada 615 7$aŅrgans (Anatomia) 676 $a610.28 676 $a610.28 702 $aYahaya$b Badrul Hisham 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 912 $a9910544848903321 996 $aOrganoid Technology for Disease Modelling and Personalized Treatment$92644873 997 $aUNINA