LEADER 04033nam 22006975 450 001 9910523778003321 005 20251113183610.0 010 $a3-030-87532-6 024 7 $a10.1007/978-3-030-87532-9 035 $a(MiAaPQ)EBC6803027 035 $a(Au-PeEL)EBL6803027 035 $a(CKB)19410601900041 035 $a(OCoLC)1286431553 035 $a(PPN)258841478 035 $a(DE-He213)978-3-030-87532-9 035 $a(EXLCZ)9919410601900041 100 $a20211110d2022 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHealthy Longevity and Immune System /$fedited by Valquiria Bueno, Graham Pawelec 205 $a1st ed. 2022. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2022. 215 $a1 online resource (208 pages) 225 1 $aHealthy Ageing and Longevity,$x2199-9015 ;$v16 311 08$aPrint version: Bueno, Valquiria Healthy Longevity and Immune System Cham : Springer International Publishing AG,c2021 9783030875312 327 $aIntroduction -- Changes in primary and secondary lymphoid organs (bone marrow, thymus, lymph nodes, spleen) -- Immune barriers (skin, mucosa) -- Innate immunity (neutrophils, monocytes, macrophages) -- Adaptive immunity (T and B lymphocytes: naïve, effector and memory phenotypes and functions) -- ReIntroduction -- Changes in primary and secondary lymphoid organs (bone marrow, thymus, lymph nodes, spleen) -- Immune barriers (skin, mucosa) -- Innate immunity (neutrophils, monocytes, macrophages) -- Adaptive immunity (T and B lymphocytes: naïve, effector and memory phenotypes and functions) -- Regulatory/suppressive cells (Treg, MDSC) -- Infections - Flu, pneumonia, COVID -- Vaccine responses -- Cancer -- Neurodegenerative disease -- Lifestyle/Interventions(physical activity, nutrition, supplements). . 330 $aThis book presents studies of the main conditions that affect health and well-being of old people. Considering the present scenario of COVID-19, the effects of this viral infection on individuals older than 65 years are also discussed. The content enables professionals of health and government for the present and future actions in this important area. Readers go through the changes occurring in organs and tissues that can interfere with susceptibility to infections, low response to vaccines, cancer, and loss of cognition during the aging process. A discussion of the central role played by the immune system in the age-related diseases and how the immunity can be impaired during the ageing process is presented. Possibilities to circumvent these conditions via healthy habits in diet, physical exercise, and new pharmacological interventions are part of the content. This book discusses how human healthy longevity is dependent, at least in part,of a functional immune system. Chapters were written for researchers in the field of aging and is especially suited for those interested in the study of immunosenescence and inflammaging affecting the health of old individuals. 410 0$aHealthy Ageing and Longevity,$x2199-9015 ;$v16 606 $aImmunology 606 $aAging 606 $aNeurosciences 606 $aNutrition 606 $aMedical sciences 606 $aImmunology 606 $aAgeing 606 $aNeuroscience 606 $aNutrition 606 $aHealth Sciences 615 0$aImmunology. 615 0$aAging. 615 0$aNeurosciences. 615 0$aNutrition. 615 0$aMedical sciences. 615 14$aImmunology. 615 24$aAgeing. 615 24$aNeuroscience. 615 24$aNutrition. 615 24$aHealth Sciences. 676 $a612.67 700 $aBueno$b Valquiria$01079074 702 $aPawelec$b G$g(Graham), 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910523778003321 996 $aHealthy Longevity and Immune System$92591514 997 $aUNINA