LEADER 04396oam 22006375 450 001 9910522570703321 005 20240117115500.0 010 $a981-15-9411-2 024 7 $a10.1007/978-981-15-9411-3 035 $a(MiAaPQ)EBC6878138 035 $a(Au-PeEL)EBL6878138 035 $a(CKB)21047797900041 035 $a(DE-He213)978-981-15-9411-3 035 $a(EXLCZ)9921047797900041 100 $a20220131d2022 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHandbook of oxidative stress in cancer $emechanistic aspects /$fedited by Sajal Chakraborti, Bimal K. Ray, Susanta Roychoudhury 205 $a1st ed. 2022. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2022. 215 $a1 online resource (2659 pages) $cillustrations (chiefly color) 225 1 $aSpringer Nature reference 311 08$aPrint version: Chakraborti, Sajal Handbook of Oxidative Stress in Cancer: Mechanistic Aspects Singapore : Springer Singapore Pte. Limited,c2022 9789811594106 320 $aIncludes bibliographical references and index. 327 $aInvolvement of ROS in thyroid cancer -- Skin cancer induced by pollution-medicated ROS -- Roles of ?-Glucans in Oxidative Stress and Cancer -- Oxidative stress in glioma and its microenvironment -- Reactive oxygen species and their contribution to carcinogenesis -- Oral cancer and oxidative stress -- Oxidative stress in genitourinary cancer -- Oxidative stress in oral cancer -- Oxidative stress and glyoxalase pathway in cancer -- ROS and EMT in multistep carcinogenesis -- Functional regulation between matrix metalloproteases and cell junction proteins in gastric cancer -- Association of oxidative stress and mitochondrial dysfunction to gynaecological malignancies -- Impact of Caenorhabdits elegans in cancdeer drug resistance and development -- Pharmacology of natural products specifically plant based mitigating cisplatin-induced cardiotoxicity and attenuating oxidative stress, inflammation and associated signalling pathways -- Scafold based selective ROS generation as viable therapeutic strategies. 330 $aThis comprehensive, up-to-date reference work compiles the scientific research on the relationship between various forms of cancer and reactive oxygen species (ROS). It is well known that ROS play a key role in the various steps leading to malignancy, this includes increase in DNA mutation rates. The book brings together exciting reviews, written by leading experts all over the world. The book is divided into four broad sections. Each section describes the role of oxidative stress and underlying mechanisms and pathways, at various stages of cancer, including its role in carcinogenesis, cancer progression and metastasis. Further, the book describes how the reactive oxygen species (ROS) modulate gene expression and signal transduction pathways in cancer. The book discusses the ways to interfere with the cancer progression, and design of anti-cancer drugs. The book provides an integrated approach for better understanding of the development phases of oxidative stress-induced cancers, and mainly the current perspectives about mechanistic aspects of cancer initiation, progression and metastasis. It is a highly resourceful book and would be extremely important to clinicians, students and researchers in the field of cancer genetics, therapeutics and oncology. 410 0$aSpringer Nature reference. 606 $aActive oxygen$xPhysiological effect 606 $aCancer 606 $aOxidative stress 606 $aEstrès oxidatiu$2thub 606 $aCàncer$2thub 606 $aOxigen actiu$2thub 606 $aEfectes fisiològics$2thub 608 $aLlibres electrònics$2thub 615 0$aActive oxygen$xPhysiological effect. 615 0$aCancer. 615 0$aOxidative stress. 615 7$aEstrès oxidatiu 615 7$aCàncer 615 7$aOxigen actiu 615 7$aEfectes fisiològics 676 $a612.22 702 $aChakraborti$b Sajal 702 $aRay$b Bimal K.$f1951- 702 $aRoychoudhury$b Susanta 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910522570703321 996 $aHandbook of Oxidative Stress in Cancer$92930722 997 $aUNINA