LEADER 03140nam 2200589 450 001 9910512168903321 005 20220919192125.0 010 $a3-030-85592-9 035 $a(MiAaPQ)EBC6824248 035 $a(Au-PeEL)EBL6824248 035 $a(CKB)20094175000041 035 $a(PPN)259385859 035 $a(EXLCZ)9920094175000041 100 $a20220825d2021 uy 0 101 0 $aeng 135 $aurcn#|||||||| 181 $ctxt$2rdacontent 181 $csti$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aFlow chemistry in drug discovery /$fJesus Alcazar, Antonio de la Hoz and Angel Di?az-Ortiz, editors 210 1$aCham, Switzerland :$cSpringer Nature Switzerland AG,$d[2021] 210 4$dİ2021 215 $a1 online resource (479 pages) $cillustrations 225 1 $aTopics in Medicinal Chemistry ;$vVolume 38 311 08$aPrint version: Alcazar, Jesus Flow Chemistry in Drug Discovery Cham : Springer International Publishing AG,c2022 9783030855918 3030855910 320 $aIncludes bibliographical references. 330 $aThis book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds. Prepared by expert contributors, the respective chapters cover not only fundamental methodologies and reactions, such as the application of catalysis, especially biocatalysis and organocatalysis; and non-conventional activation techniques, from photochemistry to electrochemistry; but also the development of new process windows, processes and reactions in drug synthesis. Particular attention is given to automatization and library synthesis, which are of great importance in the pharmaceutical industry. Readers will also find coverage on selected topics of general interest, such as how flow chemistry is contributing to drug discovery R&D in developing countries, and the green character of this enabling technology, for example in the production of raw materials for the pharmaceutical industry from waste. Given its scope, the book appeals to medicinal chemistry researchers working in academia and industry alike, as well as professionals involved in scale-up and drug development. 410 0$aTopics in medicinal chemistry (Springer (Firm)) ;$vVolume 38. 606 $aDrug development 606 $aFlow chemistry 606 $aPharmaceutical chemistry 606 $aTechnology, Pharmaceutical 606 $aDrug Discovery 606 $aChemistry$xinstrumentation 615 0$aDrug development. 615 0$aFlow chemistry. 615 0$aPharmaceutical chemistry. 615 2$aTechnology, Pharmaceutical. 615 2$aDrug Discovery. 615 2$aChemistry$xinstrumentation. 676 $a615.19 702 $aAlcazar$b Jesus 702 $aHoz$b Antonio de la 702 $aDi?az-Ortiz$b Angel 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910512168903321 996 $aFlow Chemistry in Drug Discovery$92558011 997 $aUNINA