LEADER 04208nam 22007215 450 001 9910512168903321 005 20251113185059.0 010 $a3-030-85592-9 024 7 $a10.1007/978-3-030-85592-5 035 $a(MiAaPQ)EBC6824248 035 $a(Au-PeEL)EBL6824248 035 $a(CKB)20094175000041 035 $a(PPN)259385859 035 $a(DE-He213)978-3-030-85592-5 035 $a(EXLCZ)9920094175000041 100 $a20211208d2021 u| 0 101 0 $aeng 135 $aurcn#|||||||| 181 $ctxt$2rdacontent 181 $csti$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aFlow Chemistry in Drug Discovery /$fedited by Jesus Alcazar, Antonio de la Hoz, Angel Díaz-Ortiz 205 $a1st ed. 2021. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2021. 215 $a1 online resource (479 pages) $cillustrations 225 1 $aTopics in Medicinal Chemistry,$x1862-247X ;$v38 311 08$aPrint version: Alcazar, Jesus Flow Chemistry in Drug Discovery Cham : Springer International Publishing AG,c2022 9783030855918 3030855910 320 $aIncludes bibliographical references. 327 $aFlow Chemistry in Drug Discovery: Challenges and Opportunities -- Green aspects of Flow Chemistry for Drug Discovery -- New process windows for synthesis of bioactive compounds -- Asymmetric catalysis in flow for Drug Discovery -- Organocatalysis in flow for Drug Discovery -- Biocatalysis in flow for Drug Discovery -- Photochemistry in flow for Drug Discovery -- Electrochemistry in flow for Drug Discovery -- Drug Discovery automation and library synthesis in flow -- Improved synthesis of bioactive molecules through Flow Chemistry -- Flash Chemistry in microsystems for Drug Discovery -- New biomass reagents for synthesis of bioactive compounds -- Flow Chemistry supporting access to Drug Discovery in Development countries. . 330 $aThis book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds. Prepared by expert contributors, the respective chapters cover not only fundamental methodologies and reactions, such as the application of catalysis, especially biocatalysis and organocatalysis; and non-conventional activation techniques, from photochemistry to electrochemistry; but also the development of new process windows, processes and reactions in drug synthesis. Particular attention is given to automatization and library synthesis, which are of great importance in the pharmaceutical industry. Readers will also find coverage on selected topics of general interest, such as how flow chemistry is contributing to drug discovery R&D in developing countries, and the green character of this enabling technology, for example in the production of raw materials for the pharmaceutical industry from waste. Given its scope, the book appeals to medicinal chemistry researchers working in academia and industry alike, as well as professionals involved in scale-up and drug development. 410 0$aTopics in Medicinal Chemistry,$x1862-247X ;$v38 606 $aPharmaceutical chemistry 606 $aFlow chemistry 606 $aPharmaceutical chemistry 606 $aCatalysis 606 $aChemistry, Technical 606 $aMedicinal Chemistry 606 $aFlow Chemistry 606 $aPharmaceutics 606 $aCatalysis 606 $aIndustrial Chemistry 615 0$aPharmaceutical chemistry. 615 0$aFlow chemistry. 615 0$aPharmaceutical chemistry. 615 0$aCatalysis. 615 0$aChemistry, Technical. 615 14$aMedicinal Chemistry. 615 24$aFlow Chemistry. 615 24$aPharmaceutics. 615 24$aCatalysis. 615 24$aIndustrial Chemistry. 676 $a615.19 702 $aAlcazar$b Jesus 702 $aHoz$b Antonio de la 702 $aDi?az-Ortiz$b Angel 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910512168903321 996 $aFlow Chemistry in Drug Discovery$92558011 997 $aUNINA