LEADER 05278nam 2200637Ia 450 001 9910511752303321 005 20170815123321.0 010 $a1-280-64180-0 010 $a9786610641802 010 $a0-08-046212-X 035 $a(CKB)1000000000357846 035 $a(EBL)270363 035 $a(OCoLC)271306479 035 $a(SSID)ssj0000254828 035 $a(PQKBManifestationID)12048214 035 $a(PQKBTitleCode)TC0000254828 035 $a(PQKBWorkID)10208835 035 $a(PQKB)11120592 035 $a(MiAaPQ)EBC270363 035 $a(PPN)132410583 035 $a(EXLCZ)991000000000357846 100 $a20050826d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSynthesis of essential drugs$b[electronic resource] /$fR?. S. Vardanyan, V. J. Hruby 210 $aAmsterdam ;$aLondon $cElsevier$d2006 215 $a1 online resource (635 p.) 300 $aDescription based upon print version of record. 311 $a0-444-52166-6 320 $aIncludes bibliographical references and index. 327 $afront cover; copyright; front matter; Preface; table of contents; body; General Anesthetics; Inhalation Anesthetics; Noninhalation Anesthetics; Local Anesthetics; Local Anesthetics of the Aminoether Series; Local Anesthetics of the Aminoamide Series; Topical Anesthetics; Analgesics; Opioid Analgesics; Agonists; Mixed agonists/antagonists; Opioid antagonists; Nonsteroid Anti-Inflammatory Drugs and Anti-Fever Analgesics; Salicylic acid derivatives; Pyrazolonees; p-Aminophenol derivatives; Anthranylic acid derivatives; Propionic acid derivatives; Acetic acid derivatives 327 $aIndolyl/indeneacetic acidsOxicames; Soporific Agents (Hypnotics and Sedative Drugs); Barbiturates; Long-acting barbiturates; Intermediate-acting barbiturates; Short-action barbiturates; Ultrashort-action barbiturates; Benzodiazepines; Other Hypnotics and Sedative Drugs; Anxiolytics (Tranquilizers); Benzodiazepines; Anxiolytic of Nonbenzodiazepine Structures; Antipsychotics (Neuroleptics); Phenothiazine Derivatives; Thioxanthene Derivatives; Butyrophenone Derivatives; Dihydroindolone Derivatives; Dibenzoxazepine and Dibenzdiazepine Derivatives; Diphenylbutylpiperidine Derivatives 327 $aOther NeurolepticsLithium Derivatives; Antidepressants; Tricyclic Antidepressants; Tertiary amines-representatives of tricyclic antidepressants; Secondary amines-representatives of tricyclic antidepressants; Monoaminooxidase Inhibitors; Second-Generation Antidepressants (Atypical Antidepressants); Amphetamines and Other CNS Stimulators; Central Nervous System Stimulants; Psychomotor Stimulants; Methylxanthines; Amphetamines, methylphenidate, and pemoline; Respiratory Stimulants or Analeptics; Appetite Suppressants or Anorectics; Antiepileptic Drugs; Hydantoin Derivatives; Barbiturates 327 $aSuccinimidesValproic Acid; Carbamazepine; Benzodiazepines; Acetazolamide; Oxazolidines; Antiparkinsonian Drugs; Drugs Affecting the Dopaminergic Systems of the Brain; Anticholinergic Drugs (Central Cholinoblockers); Adrenergic (Sympathomimetic) Drugs; Direct-Acting Agonists; Drugs stimulating ?- and ?-adrenoreceptors; Drugs stimulating predominantly ?-adrenoreceptors; Drugs stimulating predominantly ?-adrenoreceptors; Antiedema sympathomimetics; Indirect-Acting Agonists; Agonists of Mixed Action; Adrenoblocking Drugs; ?-Adrenoblockers; ?-Adrenoblockers; Long-lasting noncompetitive antagonists 327 $aNonselective, reversible competitive adrenoblockersReversible, competitive ?1-selective adrenoblockers; Ergot alkaloids (alkaloids of ergot); Selective ?2-adrenoblockers; Adrenergic Neuron Blockers; Cholinomimetics; Direct-Acting Cholinomimetics; Choline esters; Natural muscarinic alkaloids; Natural nicotinic alkaloids; Indirect-Acting Cholinomimetics; Reversible cholinesterase inhibitors; Carbamates; Quaternary amines; Irreversible cholinesterase inhibitors; Other organophosphorous cholinesterase inhibitors; Anticholinergic Drugs; Antimuscarinic Drugs; Alkaloids 327 $aAnticholinergics of the quaternary amine series 330 $aThis book represents an effort to express a long overdue need of compiling information which has been accumulated over the course of more than 30 years of our work in the area of the synthesis of medicinal drugs. Our effort fills obvious gaps that exist in the literature of drug synthesis. The synthesis of various groups of drugs are presented in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind - to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Pra 606 $aPharmaceutical chemistry 606 $aDrugs$xDesign 608 $aElectronic books. 615 0$aPharmaceutical chemistry. 615 0$aDrugs$xDesign. 676 $a615.19 676 $a615.7 700 $aVardanyan$b R?uben$0722711 701 $aHruby$b Victor J.$f1938-$094130 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910511752303321 996 $aSynthesis of essential drugs$91409491 997 $aUNINA